scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1011765592 |
P356 | DOI | 10.1038/SJ.ONC.1205083 |
P698 | PubMed publication ID | 11850781 |
P5875 | ResearchGate publication ID | 11510237 |
P2093 | author name string | Kathleen Collins | |
James R Mitchell | |||
P2860 | cites work | Nhp2p and Nop10p are essential for the function of H/ACA snoRNPs | Q22008508 |
Mammalian telomeres end in a large duplex loop | Q22009893 | ||
Dyskerin localizes to the nucleolus and its mislocalization is unlikely to play a role in the pathogenesis of dyskeratosis congenita | Q22010777 | ||
A telomerase component is defective in the human disease dyskeratosis congenita | Q22010917 | ||
The family of box ACA small nucleolar RNAs is defined by an evolutionarily conserved secondary structure and ubiquitous sequence elements essential for RNA accumulation | Q22065786 | ||
In vitro assembly of human H/ACA small nucleolar RNPs reveals unique features of U17 and telomerase RNAs | Q22253860 | ||
Human telomerase contains two cooperating telomerase RNA molecules | Q24291388 | ||
hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization | Q24310670 | ||
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT | Q24313396 | ||
X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions | Q24317067 | ||
Severe growth defect in mouse cells lacking the telomerase RNA component | Q47991784 | ||
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues | Q47991825 | ||
Developmental regulation of telomerase activity in human fetal tissues during gestation | Q48599863 | ||
Dyskeratosis Congenita (DC) Registry: identification of new features of DC. | Q50848237 | ||
Transfer of the human telomerase reverse transcriptase (TERT) gene into T lymphocytes results in extension of replicative potential | Q52018513 | ||
Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation. | Q52165691 | ||
Activation of a cAMP pathway and induction of melanogenesis correlate with association of p16(INK4) and p27(KIP1) to CDKs, loss of E2F-binding activity, and premature senescence of human melanocytes | Q52537213 | ||
Telomerase activity reconstituted in vitro with purified human telomerase reverse transcriptase and human telomerase RNA component | Q52579047 | ||
Telomere end-replication problem and cell aging | Q56508218 | ||
Accelerated telomere shortening in ataxia telangiectasia | Q57017468 | ||
Identification of Functional Domains and Dominant Negative Mutations in Vertebrate Telomerase RNA Using anin VivoReconstitution System | Q63384208 | ||
Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. | Q64988940 | ||
Telomerase activity concentrates in the mitotically active segments of human hair follicles | Q71937963 | ||
Accelerated telomere shortening and telomerase activation in Fanconi's anaemia | Q73165209 | ||
Up-regulation of telomerase in human B lymphocytes occurs independently of cellular proliferation and with expression of the telomerase catalytic subunit | Q73170467 | ||
Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae | Q73297605 | ||
Tissue-specific alternate splicing of human telomerase reverse transcriptase (hTERT) influences telomere lengths during human development | Q73670399 | ||
Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation | Q73720782 | ||
Dyskeratosis and ribosomal rebellion | Q74557662 | ||
Chromosomal breakage analysis in dyskeratosis congenita peripheral blood lymphocytes | Q77348076 | ||
Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions | Q78237647 | ||
Both transcriptional and posttranscriptional mechanisms regulate human telomerase template RNA levels | Q39551372 | ||
One-step affinity purification protocol for human telomerase | Q39724301 | ||
An alternate splicing variant of the human telomerase catalytic subunit inhibits telomerase activity | Q40825989 | ||
Immortalization of human CD8+ T cell clones by ectopic expression of telomerase reverse transcriptase | Q40848482 | ||
Telomerase activity does not always imply telomere maintenance | Q40977667 | ||
Dyskeratosis congenita: an inherited bone marrow failure syndrome | Q40979710 | ||
Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase | Q41035726 | ||
The human papillomavirus type 16 E6 and E7 oncoproteins dissociate cellular telomerase activity from the maintenance of telomere length | Q41109914 | ||
The frequency of immortalization of human fibroblasts and mammary epithelial cells transfected with SV40 large T-antigen | Q41517399 | ||
Immunohistochemical detection of telomerase (hTERT) protein in human cancer tissues and a subset of cells in normal tissues | Q41841480 | ||
Telomerase is not an epidermal stem cell marker and is downregulated by calcium | Q42465424 | ||
Detection of telomerase activity in malignant and nonmalignant skin conditions | Q42516900 | ||
Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow | Q42528725 | ||
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation | Q42830375 | ||
Mechanism of telomerase induction during T cell activation | Q44208409 | ||
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes | Q46069224 | ||
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs | Q46821624 | ||
Telomere shortening is proportional to the size of the G-rich telomeric 3'-overhang | Q47240761 | ||
Small nucleolar RNA-guided post-transcriptional modification of cellular RNAs | Q24535572 | ||
Identification of two RNA-binding proteins associated with human telomerase RNA | Q24548517 | ||
Human H/ACA small nucleolar RNPs and telomerase share evolutionarily conserved proteins NHP2 and NOP10 | Q24551042 | ||
Position within the host intron is critical for efficient processing of box C/D snoRNAs in mammalian cells | Q24555109 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
A comprehensive two-hybrid analysis to explore the yeast protein interactome | Q27861093 | ||
The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase | Q27935785 | ||
RNA-binding protein Nrd1 directs poly(A)-independent 3'-end formation of RNA polymerase II transcripts | Q27936766 | ||
Pseudouridine synthases: four families of enzymes containing a putative uridine-binding motif also conserved in dUTPases and dCTP deaminases | Q27939204 | ||
Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure. | Q27940038 | ||
Functional requirement of p23 and Hsp90 in telomerase complexes | Q28115669 | ||
Reconstitution of human telomerase activity in vitro | Q28116966 | ||
Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase | Q28138478 | ||
Secondary structure of vertebrate telomerase RNA | Q28138961 | ||
Unexplained aplastic anaemia, immunodeficiency, and cerebellar hypoplasia (Hoyeraal-Hreidarsson syndrome) due to mutations in the dyskeratosis congenita gene, DKC1 | Q28139353 | ||
Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle | Q28144506 | ||
Overlap of dyskeratosis congenita with the Hoyeraal-Hreidarsson syndrome | Q28145789 | ||
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
Identification of novel DKC1 mutations in patients with dyskeratosis congenita: implications for pathophysiology and diagnosis | Q28191248 | ||
TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family | Q28564535 | ||
NAP57, a mammalian nucleolar protein with a putative homolog in yeast and bacteria | Q28574203 | ||
A mammalian telomerase-associated protein | Q28595030 | ||
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis | Q29614741 | ||
A survey of telomerase activity in human cancer | Q29614858 | ||
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end | Q29615761 | ||
The RNA world of the nucleolus: two major families of small RNAs defined by different box elements with related functions | Q29616485 | ||
Reverse transcriptase motifs in the catalytic subunit of telomerase | Q29618392 | ||
Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting | Q30306373 | ||
Reversing Time: Origin of Telomerase | Q30471858 | ||
Telomere maintenance mechanisms and cellular immortalization. | Q33540084 | ||
Hematopoietic stem cells and aging | Q33654953 | ||
In vivotelomere dynamics of human hematopoietic stem cells | Q33726870 | ||
Telomeres and HIV disease | Q33863067 | ||
Telomerase activity in normal and malignant hematopoietic cells | Q33883794 | ||
Dyskeratosis congenita, telomeres and human ageing | Q33899420 | ||
Telomere dynamics in cancer progression and prevention: fundamental differences in human and mouse telomere biology | Q33912829 | ||
hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro | Q33938937 | ||
Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro | Q33959420 | ||
Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA | Q33959977 | ||
Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase | Q33966749 | ||
Mice without telomerase: what can they teach us about human cancer? | Q33995041 | ||
RNA binding domain of telomerase reverse transcriptase | Q34011552 | ||
N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo | Q34012762 | ||
Dyskeratosis congenita in all its forms | Q34071682 | ||
Telomeres and their control | Q34090772 | ||
Telomerase and human tumorigenesis | Q34136624 | ||
Modeling chromosomal instability and epithelial carcinogenesis in the telomerase-deficient mouse | Q34283802 | ||
The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo | Q34363735 | ||
Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes | Q34387542 | ||
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita | Q34514264 | ||
The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence | Q34654211 | ||
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. | Q34724924 | ||
The hTERTalpha splice variant is a dominant negative inhibitor of telomerase activity | Q34785876 | ||
Telomerase RNA function in recombinant Tetrahymena telomerase | Q35203518 | ||
Expression of telomerase activity in human endometrium is localized to epithelial glandular cells and regulated in a menstrual phase-dependent manner correlated with cell proliferation | Q35786049 | ||
The rate of telomere sequence loss in human leukocytes varies with age | Q36093340 | ||
The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex | Q36199868 | ||
Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice | Q36255827 | ||
Constitutive and regulated expression of telomerase reverse transcriptase (hTERT) in human lymphocytes | Q36338644 | ||
Telomere fluorescence measurements in granulocytes and T lymphocyte subsets point to a high turnover of hematopoietic stem cells and memory T cells in early childhood. | Q36375132 | ||
Telomere lengthening and telomerase activation during human B cell differentiation | Q36596432 | ||
Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization | Q36754020 | ||
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
Coordinate Regulation of G- and C Strand Length during New Telomere Synthesis | Q36942197 | ||
Yeast snoRNA accumulation relies on a cleavage-dependent/polyadenylation-independent 3'-processing apparatus | Q38306636 | ||
Stable expression in yeast of the mature form of human telomerase RNA depends on its association with the box H/ACA small nucleolar RNP proteins Cbf5p, Nhp2p and Nop10p | Q38668875 | ||
The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. | Q39120582 | ||
Precursors to the U3 small nucleolar RNA lack small nucleolar RNP proteins but are stabilized by La binding. | Q39454500 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 564-579 | |
P577 | publication date | 2002-01-01 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | Oncogene | Q1568657 |
P1476 | title | Telomerase in the human organism | |
P478 | volume | 21 |
Q42049785 | 18S rRNA processing requires base pairings of snR30 H/ACA snoRNA to eukaryote-specific 18S sequences |
Q36593389 | 2-(4'-CHLOROPHENYL)-1,4-BENZOQUINONE INCREASES THE FREQUENCY OF MICRONUCLEI AND SHORTENS TELOMERES. |
Q48309124 | 2009 nobel prize in physiology or medicine: telomeres and telomerase |
Q37293050 | A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs |
Q34154685 | A Cajal body-independent pathway for telomerase trafficking in mice |
Q64902276 | A DNA telomerase vaccine for canine cancer immunotherapy. |
Q34519935 | A novel RNA binding domain in tetrahymena telomerase p65 initiates hierarchical assembly of telomerase holoenzyme |
Q63384201 | A role for the Rb family of proteins in controlling telomere length |
Q50167630 | ANAT: a tool for constructing and analyzing functional protein networks |
Q34446515 | Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation |
Q37198593 | Actions of human telomerase beyond telomeres |
Q64264854 | Adult Cardiac Stem Cell Aging: A Reversible Stochastic Phenomenon? |
Q36687975 | Age-related arterial telomere uncapping and senescence is greater in women compared with men. |
Q38716151 | Aging and computational systems biology |
Q89622479 | Alternative Lengthening of Telomeres in Pediatric Cancer: Mechanisms to Therapies |
Q35131772 | Alternative lengthening of telomeres, telomerase, and cancer. |
Q33239614 | Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy |
Q36821063 | Anticancer DNA vaccine based on human telomerase reverse transcriptase generates a strong and specific T cell immune response |
Q34477907 | Assessing telomere length using surface enhanced Raman scattering |
Q54465260 | Association of TERT rs2736098 Polymorphism with Cancer Risk: a Meta-analysis |
Q39558822 | Augmented telomerase activity and reduced telomere length in parthenium-induced contact dermatitis |
Q37300355 | Avian Leukosis Virus Activation of an Antisense RNA Upstream of TERT in B-Cell Lymphomas |
Q30312045 | Beginning to understand the end of the chromosome |
Q33828733 | Behaviour of telomere and telomerase during aging and regeneration in zebrafish. |
Q34280216 | Beyond average: potential for measurement of short telomeres. |
Q36768167 | Biogenesis and intranuclear trafficking of human box C/D and H/ACA RNPs |
Q36918634 | Cancer and ageing: convergent and divergent mechanisms |
Q24540232 | Cell cycle-dependent recruitment of telomerase RNA and Cajal bodies to human telomeres |
Q24540240 | Cell cycle-regulated trafficking of human telomerase to telomeres |
Q27003892 | Cellular mechanisms of tissue fibrosis. 7. New insights into the cellular mechanisms of pulmonary fibrosis |
Q29615561 | Cellular senescence: when bad things happen to good cells |
Q36243389 | Changes in Nuclear Orientation Patterns of Chromosome 11 during Mouse Plasmacytoma Development |
Q28394371 | Characterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33 |
Q38932833 | Circulating tumor cells as a prognostic factor in patients with small cell lung cancer |
Q39041676 | Colorimetry and SERS dual-mode detection of telomerase activity: combining rapid screening with high sensitivity |
Q37093223 | Combined analysis of DNA methylome and transcriptome reveal novel candidate genes with susceptibility to bovine Staphylococcus aureus subclinical mastitis |
Q49679439 | Common mental disorders and association with telomere length. |
Q38736924 | Comparison of different methods for telomere length measurement in whole blood and blood cell subsets: Recommendations for telomere length measurement in hematological diseases |
Q48506203 | Comprehensive characterization of chorionic villi-derived mesenchymal stromal cells from human placenta. |
Q57239953 | DNA methyltransferases control telomere length and telomere recombination in mammalian cells |
Q40651914 | Delivering antisense telomerase RNA by a hybrid adenovirus/ adeno-associated virus significantly suppresses the malignant phenotype and enhances cell apoptosis of human breast cancer cells |
Q44590135 | Demethylation of the human telomerase catalytic subunit (hTERT) gene promoter reduced hTERT expression and telomerase activity and shortened telomeres |
Q35842463 | Depleting components of the THO complex causes increased telomere length by reducing the expression of the telomere-associated protein Rif1p |
Q37341340 | Differential telomerase expression in idiopathic pulmonary fibrosis and non-small cell lung cancer. |
Q36959962 | Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference |
Q46833369 | Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs |
Q54632309 | Dual roles of a variable number of tandem repeat polymorphism in the TERT gene in lung cancer |
Q64058809 | Dynamics of leukocyte telomere length in pregnant women living with HIV, and HIV-negative pregnant women: A longitudinal observational study |
Q35558515 | Dyskeratosis congenita: its link to telomerase and aplastic anaemia |
Q40464802 | Dysregulated expression of the major telomerase components in leukaemic stem cells. |
Q33860001 | Dysregulation of H/ACA ribonucleoprotein components in chronic lymphocytic leukemia |
Q31049690 | Effect of TERT and ATM on gene expression profiles in human fibroblasts. |
Q27662381 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA |
Q36642484 | Effective antitumor immunity against murine gliomas using dendritic cells transduced with hTERTC27 recombinant adenovirus |
Q31156804 | Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells |
Q34485779 | Effects of long-term culture on human embryonic stem cell aging. |
Q39793502 | Enhanced differentiation and clonogenicity of human endometrial polyp stem cells |
Q40453395 | Enhanced oncolysis by a tropism-modified telomerase-specific replication-selective adenoviral agent OBP-405 ('Telomelysin-RGD'). |
Q34988020 | Environmental stresses disrupt telomere length homeostasis |
Q39944681 | Epigenetic regulation of telomeres in human cancer. |
Q28714820 | Exclusion of Exon 2 Is a Common mRNA Splice Variant of Primate Telomerase Reverse Transcriptases |
Q46044021 | Expression of the telomeric retrotransposon HeT-A in Drosophila melanogaster is correlated with cell proliferation |
Q35370390 | Expression profile of telomere-associated genes in multiple myeloma. |
Q41549644 | Five gene variants in nonagenarians, centenarians and average individuals |
Q34615436 | Flow cytometry and FISH to measure the average length of telomeres (flow FISH). |
Q38234418 | From experimental design to functional gene networks: DNA microarray contribution to skin ageing research |
Q24299999 | Functional conservation of the telomerase protein Est1p in humans |
Q34369713 | Functional interaction between DNA-PKcs and telomerase in telomere length maintenance |
Q35597309 | Further delineation of the congenital form of X-linked dyskeratosis congenita (Hoyeraal-Hreidarsson syndrome). |
Q34082438 | Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways |
Q59128040 | Genetic Risk for Psychiatric Disorders and Telomere Length |
Q34506827 | Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies |
Q38550343 | Genetic and epigenetic trends in telomere research: a novel way in immunoepigenetics. |
Q24597936 | Genetic heterogeneity in autosomal recessive dyskeratosis congenita with one subtype due to mutations in the telomerase-associated protein NOP10 |
Q55262410 | Genetic polymorphisms in the TERT gene and susceptibility to non-small cell lung cancer in a Chinese Han population. |
Q39186515 | Genetic polymorphisms of TERT and CLPTM1L and risk of lung cancer: a case-control study in northeast Chinese male population |
Q36809661 | Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome |
Q33298581 | Genetic variation in five genes important in telomere biology and risk for breast cancer |
Q33418117 | Genetic variation in telomere maintenance genes, telomere length, and lung cancer susceptibility |
Q33221984 | Genetic variation, nucleotide diversity, and linkage disequilibrium in seven telomere stability genes suggest that these genes may be under constraint |
Q24305322 | Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells |
Q36240265 | HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes |
Q35990651 | Hematopoietic stem-cell behavior in nonhuman primates |
Q54983938 | Hexokinase 2 is a molecular bridge linking telomerase and autophagy. |
Q47379639 | HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis |
Q34236694 | Human arteries engineered in vitro |
Q39794066 | Human chorion-derived stem cells: changes in stem cell properties during serial passage |
Q36360681 | Human diseases of telomerase dysfunction: insights into tissue aging |
Q35131789 | Human epithelial cell immortalization as a step in carcinogenesis |
Q29147418 | Human replication protein A unfolds telomeric G-quadruplexes |
Q36490477 | Human skeletal muscle feed arteries: evidence of regulatory potential |
Q42057695 | Human telomerase RNA and box H/ACA scaRNAs share a common Cajal body-specific localization signal. |
Q37810521 | Human telomerase activity regulation. |
Q24602611 | Identification of PITX1 as a TERT suppressor gene located on human chromosome 5 |
Q38348375 | Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation |
Q33231582 | Identification of the determinants for the specific recognition of single-strand telomeric DNA by Cdc13 |
Q41909243 | Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines |
Q36535886 | Imetelstat (a telomerase antagonist) exerts off‑target effects on the cytoskeleton |
Q36255511 | Immortalized cells as experimental models to study cancer. |
Q26825812 | Implications of telomere‐independent activities of telomerase reverse transcriptase in human cancer |
Q36346931 | Induction of senescence in cancer cells by the G-quadruplex stabilizer, BMVC4, is independent of its telomerase inhibitory activity |
Q28540640 | Inhibition of human dyskerin as a new approach to target ribosome biogenesis |
Q38303127 | Inhibition of telomerase activity by NME2: impact on metastasis suppression? |
Q28066805 | Integrins in the Spotlight of Cancer |
Q33196380 | Interaction of an Arabidopsis RNA-binding protein with plant single-stranded telomeric DNA modulates telomerase activity |
Q51091931 | Introduction to Telomeres and Telomerase |
Q33717429 | Investigation of human telomerase holoenzyme assembly, activity, and processivity using disease-linked subunit variants |
Q37908470 | Is telomerase a viable target in cancer? |
Q54257233 | Is there a connection between inflammation, telomerase activity and the transcriptional status of telomerase reverse transcriptase in renal failure? |
Q37247601 | Isolation and characterization of a spontaneously immortalized multipotent mesenchymal cell line derived from mouse subcutaneous adipose tissue |
Q53586962 | Isolation and characterization of outer root sheath melanocytes of human hair follicles |
Q34344690 | Leukocyte telomere length in HIV-infected and HIV-exposed uninfected children: shorter telomeres with uncontrolled HIV viremia |
Q41546239 | Long Telomeres Do Not Affect Cellular Fitness in Yeast |
Q54683150 | Lymphocyte telomere dynamics and telomerase activity in inflammatory bowel disease: effect of drugs and smoking. |
Q35250688 | MMP-9 silencing regulates hTERT expression via β1 integrin-mediated FAK signaling and induces senescence in glioma xenograft cells |
Q35569699 | Mammalian telomeres and telomerase: why they matter for cancer and aging |
Q47986912 | Mec1ATR is needed for extensive telomere elongation in response to ethanol in yeast |
Q28728958 | Mechanisms Limiting Body Growth in Mammals |
Q28253085 | Mechanisms of action of TGF-beta in cancer: evidence for Smad3 as a repressor of the hTERT gene |
Q22305707 | Mesenchymal stem cell therapy in lung disorders: Pathogenesis of lung diseases and mechanism of action of mesenchymal stem cell |
Q60303743 | Metformin and insulin treatment prevent placental telomere attrition in boys exposed to maternal diabetes |
Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
Q40473633 | Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines. |
Q40407926 | Mitotic cyclins regulate telomeric recombination in telomerase-deficient yeast cells. |
Q50131963 | Modulation of Telomerase Activity in Cancer Cells by Dietary Compounds: A Review |
Q35560090 | Molecular markers in cervical cytology |
Q28540156 | Molecular recognition in complexes of TRF proteins with telomeric DNA |
Q28507063 | Mouse dyskerin mutations affect accumulation of telomerase RNA and small nucleolar RNA, telomerase activity, and ribosomal RNA processing |
Q35003946 | Mouse models to study the role of telomeres in cancer, aging and DNA repair |
Q40269031 | Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance |
Q41788519 | Non-radioactive assay methods for the assessment of telomerase activity and telomere length |
Q35553879 | Novel Perspective: Focusing on the X Chromosome in Reproductive Cancers |
Q38050774 | Nuclear and Mitochondrial DNA Repair in Selected Eukaryotic Aging Model Systems |
Q58555658 | Pharmacoepigenomic Interventions as Novel Potential Treatments for Alzheimer's and Parkinson's Diseases |
Q37022486 | Physiological assembly and activity of human telomerase complexes |
Q61051287 | Proliferative defects in dyskeratosis congenita skin keratinocytes are corrected by expression of the telomerase reverse transcriptase, TERT, or by activation of endogenous telomerase through expression of papillomavirus E6/E7 or the telomerase RNA c |
Q38453566 | Protein expression dynamics during replicative senescence of endothelial cells studied by 2-D difference in-gel electrophoresis. |
Q27678680 | Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo |
Q39114434 | RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radiosensitivity |
Q36121457 | RNAi targeting of hTERT gene expression induces apoptosis and inhibits the proliferation of lung cancer cells |
Q35119963 | Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo |
Q28119138 | Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain |
Q38097516 | Regulation of snoRNAs in Cancer: Close Encounters with Interferon |
Q34180715 | Regulation of the human catalytic subunit of telomerase (hTERT) |
Q36261268 | Relative Telomere Repeat Mass in Buccal and Leukocyte-Derived DNA. |
Q38330053 | Relief of p53-mediated telomerase suppression by p73. |
Q53384592 | Replication of results of genome‐wide association studies on lung cancer susceptibility loci in a Korean population |
Q41956967 | Role of Telomerase Reverse Transcriptase in Glial Scar Formation After Spinal Cord Injury in Rats |
Q35169573 | Role of mammalian Rad54 in telomere length maintenance |
Q36164534 | Role of telomerase in hematopoietic stem cells |
Q34633162 | Role of telomeres and telomerase in cancer |
Q35921607 | Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme |
Q34439644 | SIRT1 contributes to telomere maintenance and augments global homologous recombination |
Q41894354 | Selected Telomere Length Changes and Aberrant Three-dimensional Nuclear Telomere Organization during Fast-Onset Mouse Plasmacytomas |
Q53177167 | Silent gastro-oesophageal reflux and microaspiration in IPF: mounting evidence for anti-reflux therapy?: Figure 1– |
Q35017754 | SnoRNA microarray analysis reveals changes in H/ACA and C/D RNA levels caused by dyskerin ablation in mouse liver |
Q24653322 | Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA |
Q34446174 | Studies on the minimal lengths required for DNA primers to be extended by the Tetrahymena telomerase: implications for primer positioning by the enzyme |
Q40708285 | Subnuclear shuttling of human telomerase induced by transformation and DNA damage. |
Q53882699 | TELOMERASE ACTIVATOR1 induces telomerase activity and potentiates responses to auxin in Arabidopsis |
Q92899126 | TERT rs10069690 polymorphism and cancers risk: A meta-analysis |
Q24655738 | TINF2, a component of the shelterin telomere protection complex, is mutated in dyskeratosis congenita |
Q33418271 | TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs |
Q42070222 | Targeting cancer stem cell propagation with palbociclib, a CDK4/6 inhibitor: Telomerase drives tumor cell heterogeneity |
Q36484571 | Targeting telomerase for cancer therapeutics |
Q36017631 | Targeting telomerase-expressing cancer cells |
Q39111969 | Telomerase Mechanism of Telomere Synthesis |
Q34785598 | Telomerase RNA Accumulates in Cajal Bodies in Human Cancer Cells |
Q38060194 | Telomerase RNA biosynthesis and processing |
Q40519021 | Telomerase RNA deficiency in peripheral blood mononuclear cells in X-linked dyskeratosis congenita |
Q24680286 | Telomerase RNA level limits telomere maintenance in X-linked dyskeratosis congenita |
Q37497995 | Telomerase at the intersection of cancer and aging |
Q63384203 | Telomerase beyond telomeres |
Q36255500 | Telomerase dysfunction and dyskeratosis congenita |
Q35558080 | Telomerase expression and telomere length in breast cancer and their associations with adjuvant treatment and disease outcome |
Q40037721 | Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation |
Q36119587 | Telomerase reverses epidermal hair follicle stem cell defects and loss of long-term survival associated with critically short telomeres |
Q36506309 | Telomerase therapeutics for cancer: challenges and new directions |
Q26739948 | Telomerase: The Devil Inside |
Q34979724 | Telomerase: a target for cancer therapeutics |
Q37775786 | Telomerase: an RNP enzyme synthesizes DNA. |
Q38587987 | Telomere Dysfunction, Chromosomal Instability and Cancer. |
Q33194487 | Telomere Length in Subpopulations of Human Hematopoietic Cells |
Q36758330 | Telomere and telomerase in stem cells |
Q92484283 | Telomere attrition: metabolic regulation and signalling function? |
Q35692612 | Telomere biology of human hematopoietic stem cells |
Q37305023 | Telomere extension occurs at most chromosome ends and is uncoupled from fill-in in human cancer cells |
Q92838351 | Telomere length and aging-related outcomes in humans: A Mendelian randomization study in 261,000 older participants |
Q47144765 | Telomere length heterogeneity in placenta revealed with high-resolution telomere length analysis |
Q64068291 | Telomere length is associated with childhood trauma in patients with severe mental disorders |
Q51832611 | Telomere length measurements in leukocyte subsets by automated multicolor flow-FISH. |
Q34689235 | Telomere length, stem cells and aging |
Q35847856 | Telomere loss, senescence, and genetic instability in CD4+ T lymphocytes overexpressing hTERT. |
Q34988280 | Telomere maintenance and cancer -- look, no telomerase. |
Q35544622 | Telomere maintenance and disease |
Q36376310 | Telomere mean length in patients with diabetic retinopathy |
Q41918210 | Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. |
Q73308984 | Telomere shortening in cultured autografts of patients with burns |
Q28472826 | Telomere shortening sensitizes cancer cells to selected cytotoxic agents: in vitro and in vivo studies and putative mechanisms |
Q73308966 | Telomere shortening: significant for keratinocyte grafting? |
Q35137119 | Telomere structure, function and maintenance in Arabidopsis |
Q47115344 | Telomere tracking from birth to adulthood and residential traffic exposure. |
Q34784471 | Telomere-regulating genes and the telomere interactome in familial cancers. |
Q64084421 | Telomeres and Telomerase in Cutaneous Squamous Cell Carcinoma |
Q35062454 | Telomeres and cancer: a tale with many endings |
Q29615353 | Telomeres and human disease: ageing, cancer and beyond |
Q35131781 | Telomeres in cancer and aging: lessons from the mouse |
Q47670265 | Telomeres in dyskeratosis congenita |
Q38101746 | Telomeres in lung disease |
Q39584343 | The Alfin-like homeodomain finger protein AL5 suppresses multiple negative factors to confer abiotic stress tolerance in Arabidopsis |
Q55096010 | The Emerging Roles for Telomerase in the Central Nervous System. |
Q36931009 | The PUA domain - a structural and functional overview |
Q38042771 | The Role of Telomeres in Musculoskeletal Diseases |
Q53115661 | The TERT MNS16A polymorphism contributes to cancer susceptibility: Meta-analysis of the current studies |
Q39420706 | The Telomeric Complex and Metabolic Disease |
Q37344295 | The association between leukocyte telomere length and cigarette smoking, dietary and physical variables, and risk of prostate cancer |
Q34101736 | The association of telomere length and genetic variation in telomere biology genes |
Q38313087 | The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity. |
Q34042917 | The biogenesis and regulation of telomerase holoenzymes |
Q50655055 | The changes of leukocyte telomere length and telomerase activity after sitagliptin intervention in newly diagnosed type 2 diabetes |
Q36761196 | The epigenetic regulation of mammalian telomeres |
Q36221550 | The importance of the telomere and telomerase system in hematological malignancies |
Q38353839 | The influence of the telomere-telomerase system on diabetes mellitus and its vascular complications |
Q34751815 | The longest telomeres: a general signature of adult stem cell compartments |
Q38348816 | The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro |
Q42627757 | The p53/p21(WAF/CIP) pathway mediates oxidative stress and senescence in dyskeratosis congenita cells with telomerase insufficiency. |
Q36516357 | The role of telomere biology in bone marrow failure and other disorders |
Q36948644 | The role of telomeres in the ageing of human skin. |
Q47229385 | Tight co-twin similarity of monozygotic twins for hTERT protein level of T cell subsets, for telomere length and mitochondrial DNA copy number, but not for telomerase activity |
Q28256480 | Transcriptional regulation of telomerase activity: roles of the the Ets transcription factor family |
Q38288984 | Treating Cancer by Targeting Telomeres and Telomerase |
Q34050452 | Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA. |
Q39126017 | Ultrasensitive Telomerase Activity Detection by Telomeric Elongation Controlled Surface Enhanced Raman Scattering |
Q35989413 | Very short telomere length by flow fluorescence in situ hybridization identifies patients with dyskeratosis congenita |
Q51091922 | Visualization of Human Telomerase Localization by Fluorescence Microscopy Techniques |
Q92660799 | Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity |
Q33951786 | Worldwide genetic structure in 37 genes important in telomere biology |
Q34616697 | p53 governs telomere regulation feedback too, via TRF2 |
Search more.