scholarly article | Q13442814 |
P50 | author | Jerry W Shay | Q89873929 |
P2093 | author name string | W E Wright | |
L P Ford | |||
X Yi | |||
S E Holt | |||
M Ouellette | |||
D L Aisner | |||
V M Tesmer | |||
B C Frank | |||
P2860 | cites work | CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice | Q24286950 |
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | Q24310670 | ||
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT | Q24313396 | ||
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats | Q24339608 | ||
Human telomerase contains evolutionarily conserved catalytic and structural subunits | Q24604009 | ||
Ciliate telomerase RNA structural features | Q24629436 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
Functional requirement of p23 and Hsp90 in telomerase complexes | Q28115669 | ||
Reconstitution of human telomerase activity in vitro | Q28116966 | ||
Telomerase RNAs of different ciliates have a common secondary structure and a permuted template | Q28240524 | ||
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas | Q28258624 | ||
Domain interactions in E. coli SRP: stabilization of M domain by RNA is required for effective signal sequence modulation of NG domain | Q47862999 | ||
Inhibition of human telomerase activity by peptide nucleic acids | Q47960865 | ||
Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme | Q48072977 | ||
Boundary elements of the Tetrahymena telomerase RNA template and alignment domains | Q71738168 | ||
The RNA component of human telomerase | Q28288330 | ||
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts | Q28306745 | ||
TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family | Q28564535 | ||
A mammalian telomerase-associated protein | Q28595030 | ||
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers | Q28776783 | ||
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis | Q29614741 | ||
Telomerase catalytic subunit homologs from fission yeast and human | Q29615387 | ||
A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end | Q29615761 | ||
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes | Q29617061 | ||
TLC1: template RNA component of Saccharomyces cerevisiae telomerase | Q29618197 | ||
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes | Q29618293 | ||
Reverse transcriptase motifs in the catalytic subunit of telomerase | Q29618392 | ||
Self-assembly of a group I intron active site from its component tertiary structural domains. | Q30463736 | ||
Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax | Q30472352 | ||
Functional Evidence for an RNA Template in Telomerase | Q33998306 | ||
The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence | Q34654211 | ||
Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitro | Q34655881 | ||
Functionally interacting telomerase RNAs in the yeast telomerase complex | Q35194966 | ||
Telomerase RNA function in recombinant Tetrahymena telomerase | Q35203518 | ||
Specific telomerase RNA residues distant from the template are essential for telomerase function | Q35210631 | ||
Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. | Q35912728 | ||
The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex | Q36199868 | ||
Inhibition of human telomerase by 2'-O-methyl-RNA | Q36312946 | ||
The catalytic subunit of yeast telomerase | Q36558592 | ||
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
Expression of mouse telomerase catalytic subunit in embryos and adult tissues. | Q37470406 | ||
Architecture of telomerase RNA. | Q37639292 | ||
Identification of determinants for inhibitor binding within the RNA active site of human telomerase using PNA scanning | Q38342698 | ||
One-step affinity purification protocol for human telomerase | Q39724301 | ||
Modifications of a telomeric repeat amplification protocol (TRAP) result in increased reliability, linearity and sensitivity | Q40395982 | ||
A conserved pseudoknot in telomerase RNA | Q40509631 | ||
Cellular delivery of peptide nucleic acids and inhibition of human telomerase | Q40947066 | ||
Telomerase activity does not always imply telomere maintenance | Q40977667 | ||
Molecular cloning of bovine telomerase RNA. | Q40988429 | ||
Reconstitution of wild-type or mutant telomerase activity in telomerase-negative immortal human cells | Q41036325 | ||
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase | Q41053498 | ||
Functional characterization and developmental regulation of mouse telomerase RNA. | Q41306667 | ||
Induced folding in RNA-protein recognition: more than a simple molecular handshake | Q41698041 | ||
Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation | Q42830375 | ||
A conserved secondary structure for telomerase RNA | Q44060757 | ||
Runaway telomere elongation caused by telomerase RNA gene mutations | Q46144742 | ||
Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro | Q46806433 | ||
Independent ligand-induced folding of the RNA-binding domain and two functionally distinct antitermination regions in the phage lambda N protein | Q47862787 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 6207-6216 | |
P577 | publication date | 1999-09-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro | |
P478 | volume | 19 |
Q34012344 | A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA. |
Q24817124 | A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation |
Q42381247 | A novel TERC CR4/CR5 domain mutation causes telomere disease via decreased TERT binding |
Q35965093 | A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase |
Q35534966 | A second essential function of the Est1-binding arm of yeast telomerase RNA. |
Q37570590 | A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein |
Q36421764 | An alternative telomerase RNA in Arabidopsis modulates enzyme activity in response to DNA damage |
Q34365513 | Analysis of a long-range interaction between conserved domains of human telomerase RNA. |
Q35097599 | Analysis of telomerase activity and detection of its catalytic subunit, hTERT. |
Q24514779 | Analysis of the structure of human telomerase RNA in vivo |
Q35131769 | Biochemical aspects of telomerase function |
Q39887663 | Comprehensive structure-function analysis of the core domain of human telomerase RNA. |
Q30459426 | Contributions of the TEL-patch amino acid cluster on TPP1 to telomeric DNA synthesis by human telomerase |
Q33935577 | Coordinated DNA dynamics during the human telomerase catalytic cycle |
Q34447509 | Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility |
Q36959962 | Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference |
Q46833369 | Distinct biogenesis pathways for human telomerase RNA and H/ACA small nucleolar RNAs |
Q27662381 | Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA |
Q30450302 | Engineering cis-telomerase RNAs that add telomeric repeats to themselves |
Q38311742 | Expression of hTERT and hTR in cis reconstitutes and active human telomerase ribonucleoprotein |
Q33852153 | Functional analysis of the pseudoknot structure in human telomerase RNA. |
Q24299999 | Functional conservation of the telomerase protein Est1p in humans |
Q33969441 | Functional multimerization of the human telomerase reverse transcriptase |
Q39458154 | Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions |
Q47858939 | Hepatocyte nuclear factor 4A improves hepatic differentiation of immortalized adult human hepatocytes and improves liver function and survival |
Q33966749 | Heterogeneous nuclear ribonucleoproteins C1 and C2 associate with the RNA component of human telomerase |
Q90243303 | How RNAi machinery enters the world of telomerase |
Q39097445 | Human telomerase RNA-protein interactions |
Q28138478 | Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase |
Q24533247 | Human telomerase and its regulation |
Q63384208 | Identification of Functional Domains and Dominant Negative Mutations in Vertebrate Telomerase RNA Using anin VivoReconstitution System |
Q35626186 | Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT. |
Q34146318 | InTERTpreting telomerase structure and function |
Q26823394 | It all comes together at the ends: telomerase structure, function, and biogenesis |
Q40481869 | Measuring Telomerase Activity in Senescent Human T Cells Upon Genetic Modification. |
Q89475689 | Mechanisms of template handling and pseudoknot folding in human telomerase and their manipulation to expand the sequence repertoire of processive repeat synthesis |
Q27640301 | Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. |
Q34012762 | N-terminal domains of the human telomerase catalytic subunit required for enzyme activity in vivo |
Q31038583 | Natural and pharmacological regulation of telomerase |
Q36480863 | Physical Connectivity Mapping by Circular Permutation of Human Telomerase RNA Reveals New Regions Critical for Activity and Processivity |
Q37022486 | Physiological assembly and activity of human telomerase complexes |
Q24550780 | Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding |
Q46109951 | Processive utilization of the human telomerase template: lack of a requirement for template switching |
Q34011552 | RNA binding domain of telomerase reverse transcriptase |
Q37317740 | RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP. |
Q35656533 | RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency |
Q91522991 | Regulation of human telomerase in homeostasis and disease |
Q34130110 | Ribonucleoprotein multimers and their functions |
Q28138961 | Secondary structure of vertebrate telomerase RNA |
Q41644089 | Single-molecule FRET reveals the folding dynamics of the human telomerase RNA pseudoknot domain |
Q34546169 | Small nucleolar RNAs: versatile trans-acting molecules of ancient evolutionary origin. |
Q24653322 | Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA |
Q39793420 | Stem-loop IV of tetrahymena telomerase RNA stimulates processivity in trans |
Q27683630 | Structural basis for protein-RNA recognition in telomerase |
Q37349785 | Structural elements required for association of the Saccharomyces cerevisiae telomerase RNA with the Est2 reverse transcriptase |
Q40284536 | Structural features of mouse telomerase RNA are responsible for the lower activity of mouse telomerase versus human telomerase |
Q54659396 | Structure and function of the smallest vertebrate telomerase RNA from teleost fish. |
Q41457306 | Structure of stem-loop IV of Tetrahymena telomerase RNA. |
Q37472153 | Structure-function relationships in telomerase genes. |
Q34547087 | Telomerase RNA structure and function: implications for dyskeratosis congenita. |
Q64911093 | Telomerase and Telomeres in Endometrial Cancer. |
Q34535632 | Telomerase in the human organism |
Q33951245 | Telomerase trafficking and assembly in Xenopus oocytes |
Q33589597 | Template boundary definition in mammalian telomerase |
Q41734113 | Template boundary in a yeast telomerase specified by RNA structure |
Q34363735 | The La antigen associates with the human telomerase ribonucleoprotein and influences telomere length in vivo |
Q38313087 | The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity. |
Q28585522 | The functional requirement of two structural domains within telomerase RNA emerged early in eukaryotes |
Q84918114 | The human telomerase catalytic subunit and viral telomerase RNA reconstitute a functional telomerase complex in a cell-free system, but not in human cells |
Q34364124 | The snoRNA domain of vertebrate telomerase RNA functions to localize the RNA within the nucleus |
Q27641175 | The solution structure of an essential stem-loop of human telomerase RNA |
Q34366284 | The structure of an enzyme-activating fragment of human telomerase RNA. |
Q27642573 | YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA. |
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