| scholarly article | Q13442814 |
| P356 | DOI | 10.1128/MCB.21.18.6151-6160.2001 |
| P8608 | Fatcat ID | release_mg5zs6uubvgk5klmnjjflid6ru |
| P932 | PMC publication ID | 87332 |
| P698 | PubMed publication ID | 11509658 |
| P5875 | ResearchGate publication ID | 11835054 |
| P2093 | author name string | Zhou W | |
| Beattie TL | |||
| Harrington L | |||
| Robinson MO | |||
| P2860 | cites work | A telomerase component is defective in the human disease dyskeratosis congenita | Q22010917 |
| Human telomerase contains two cooperating telomerase RNA molecules | Q24291388 | ||
| hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization | Q24310670 | ||
| Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT | Q24313396 | ||
| Identification of two RNA-binding proteins associated with human telomerase RNA | Q24548517 | ||
| Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding | Q24550780 | ||
| Human telomerase contains evolutionarily conserved catalytic and structural subunits | Q24604009 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein | Q27931011 | ||
| Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. | Q27931258 | ||
| The Est3 protein is a subunit of yeast telomerase | Q27933462 | ||
| Eukaryotic DNA polymerases in DNA replication and DNA repair | Q27933940 | ||
| Functional requirement of p23 and Hsp90 in telomerase complexes | Q28115669 | ||
| Reconstitution of human telomerase activity in vitro | Q28116966 | ||
| Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo | Q28140790 | ||
| Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle | Q28144506 | ||
| The preparation of subtilisn-modified ribonuclease and the separation of the peptide and protein components | Q28185004 | ||
| Principles that govern the folding of protein chains | Q28236872 | ||
| The RNA component of human telomerase | Q28288330 | ||
| Telomere length regulation | Q28290143 | ||
| TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family | Q28564535 | ||
| A mammalian telomerase-associated protein | Q28595030 | ||
| The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers | Q28776783 | ||
| Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor | Q29547710 | ||
| Telomerase catalytic subunit homologs from fission yeast and human | Q29615387 | ||
| A box H/ACA small nucleolar RNA-like domain at the human telomerase RNA 3' end | Q29615761 | ||
| Reverse transcriptase motifs in the catalytic subunit of telomerase | Q29618392 | ||
| Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting | Q30306373 | ||
| Self-assembly of a group I intron active site from its component tertiary structural domains. | Q30463736 | ||
| Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang | Q30469368 | ||
| Reversing time: origin of telomerase | Q30471858 | ||
| RNA-induced changes in the activity of the endonuclease encoded by the R2 retrotransposable element | Q33774211 | ||
| Stable association of hsp90 and p23, but Not hsp70, with active human telomerase | Q33939931 | ||
| Two inactive fragments of the integral RNA cooperate to assemble active telomerase with the human protein catalytic subunit (hTERT) in vitro | Q33959420 | ||
| Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase | Q33964637 | ||
| Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex | Q33965566 | ||
| Positive and negative regulation of telomerase access to the telomere | Q34030866 | ||
| Protein Complementation | Q35010244 | ||
| Functionally interacting telomerase RNAs in the yeast telomerase complex | Q35194966 | ||
| The reverse transcriptase component of the Tetrahymena telomerase ribonucleoprotein complex | Q36199868 | ||
| Cloning, expression, and purification of a catalytic fragment of Moloney murine leukemia virus reverse transcriptase: crystallization of nucleic acid complexes. | Q36281093 | ||
| Processing of nontelomeric 3' ends by telomerase: default template alignment and endonucleolytic cleavage | Q36560631 | ||
| Group II intron domain 5 facilitates a trans-splicing reaction | Q36790013 | ||
| Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types. | Q36885740 | ||
| Association of the Est1 protein with telomerase activity in yeast | Q37677320 | ||
| Gel shift and UV cross-linking analysis of Tetrahymena telomerase | Q38296586 | ||
| The thumb domain of the P51-subunit is essential for activation of HIV reverse transcriptase | Q38318388 | ||
| Analysis of the polymerization kinetics of homodimeric EIAV p51/51 reverse transcriptase implies the formation of a polymerase active site identical to heterodimeric EIAV p66/51 reverse transcriptase | Q38333840 | ||
| Functional regions of human telomerase reverse transcriptase and human telomerase RNA required for telomerase activity and RNA-protein interactions | Q39458154 | ||
| Sequence-specific DNA primer effects on telomerase polymerization activity | Q40656443 | ||
| The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit | Q41108271 | ||
| The role of the EST genes in yeast telomere replication | Q41730845 | ||
| Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention. | Q45860281 | ||
| The Tetrahymena p80/p95 complex is required for proper telomere length maintenance and micronuclear genome stability. | Q46015316 | ||
| Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme | Q48072977 | ||
| Telomerase and retrotransposons: which came first? | Q56902974 | ||
| Telomerase primer specificity and chromosome healing | Q59021421 | ||
| Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase | Q59021450 | ||
| Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta. | Q64988940 | ||
| Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation | Q72829853 | ||
| Est1 and Cdc13 as comediators of telomerase access | Q73042124 | ||
| Functional reconstitution of human telomerase expressed in Saccharomyces cerevisiae | Q73297605 | ||
| Cell cycle restriction of telomere elongation | Q73761959 | ||
| All's well that ends well | Q74044419 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 6151-6160 | |
| P577 | publication date | 2001-09-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | Functional multimerization of the human telomerase reverse transcriptase | |
| P478 | volume | 21 |
| Q24612601 | A dimeric structure for archaeal box C/D small ribonucleoproteins |
| Q35965093 | A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase |
| Q28116246 | An anchor site-type defect in human telomerase that disrupts telomere length maintenance and cellular immortalization |
| Q35131769 | Biochemical aspects of telomerase function |
| Q34285674 | C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity |
| Q35856762 | Characterization of physical and functional anchor site interactions in human telomerase |
| Q40408531 | Cloning and expression of the reverse transcriptase component of pufferfish (Fugu rubripes) telomerase |
| Q39887663 | Comprehensive structure-function analysis of the core domain of human telomerase RNA. |
| Q34699797 | Direct involvement of the TEN domain at the active site of human telomerase |
| Q36959962 | Disease-associated human telomerase RNA variants show loss of function for telomere synthesis without dominant-negative interference |
| Q35529338 | Dyskeratosis congenita as a disorder of telomere maintenance |
| Q33315749 | Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance. |
| Q27932081 | Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction |
| Q37323568 | Function, replication and structure of the mammalian telomere |
| Q33852153 | Functional analysis of the pseudoknot structure in human telomerase RNA. |
| Q53554267 | Functional characterization of yeast telomerase RNA dimerization. |
| Q39677546 | Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit |
| Q40763366 | Functional organization of repeat addition processivity and DNA synthesis determinants in the human telomerase multimer |
| Q34506827 | Genetic Variations in Telomere Maintenance, with Implications on Tissue Renewal Capacity and Chronic Disease Pathologies |
| Q24299861 | Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase |
| Q24533247 | Human telomerase and its regulation |
| Q39554378 | Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation |
| Q28476202 | Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo |
| Q54655769 | In vitro dimerization of telomerase protein Est3p is stimulated by magnesium cations. |
| Q34146318 | InTERTpreting telomerase structure and function |
| Q34284600 | Interactions between telomerase and primase physically link the telomere and chromosome replication machinery |
| Q40578181 | Long-term molecular and cellular stability of human neural stem cell lines. |
| Q38291849 | Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate. |
| Q38294819 | Multiple DNA-binding sites in Tetrahymena telomerase |
| Q28589866 | Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo |
| Q31038583 | Natural and pharmacological regulation of telomerase |
| Q34535628 | New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin |
| Q27934811 | Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA |
| Q34367049 | Oligomerization of the telomerase reverse transcriptase from Euplotes crassus |
| Q36589155 | Opportunities and challenges for selected emerging technologies in cancer epidemiology: mitochondrial, epigenomic, metabolomic, and telomerase profiling |
| Q46109951 | Processive utilization of the human telomerase template: lack of a requirement for template switching |
| Q41916619 | Regulation of 5' template usage and incorporation of noncognate nucleotides by human telomerase |
| Q28119138 | Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain |
| Q24603295 | Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1 |
| Q34130110 | Ribonucleoprotein multimers and their functions |
| Q35125971 | Role of Telomeres and Telomerase in the Pathogenesis of Human Cancer |
| Q25255779 | Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo |
| Q39219071 | Single-Molecule Studies of Telomeres and Telomerase |
| Q57401361 | Single-molecule analysis of human telomerase monomer |
| Q30437549 | Soluble domains of telomerase reverse transcriptase identified by high-throughput screening |
| Q28115347 | Structure of active dimeric human telomerase |
| Q27651872 | Structure of the Tribolium castaneum telomerase catalytic subunit TERT |
| Q37472153 | Structure-function relationships in telomerase genes. |
| Q34547087 | Telomerase RNA structure and function: implications for dyskeratosis congenita. |
| Q37532245 | Telomerase activity-independent function of TERT allows glioma cells to attain cancer stem cell characteristics by inducing EGFR expression |
| Q42102615 | Telomerase gene expression in the chicken: Telomerase RNA (TR) and reverse transcriptase (TERT) transcript profiles are tissue-specific and correlate with telomerase activity |
| Q34989394 | Telomerase: biochemical considerations for enzyme and substrate. |
| Q35193731 | Telomere maintenance and DNA replication: how closely are these two connected? |
| Q30311376 | Tetrahymena telomerase is active as a monomer |
| Q39792077 | The C terminus of the human telomerase reverse transcriptase is a determinant of enzyme processivity |
| Q33760211 | The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization |
| Q28975759 | The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis |
| Q34042917 | The biogenesis and regulation of telomerase holoenzymes |
| Q24599906 | The genetics of dyskeratosis congenita |
| Q42086662 | The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1. |
| Q34146428 | The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase |
| Q38290133 | The nucleolar localization domain of the catalytic subunit of human telomerase |
| Q33604489 | The protein subunit of telomerase displays patterns of dynamic evolution and conservation across different metazoan taxa. |
| Q42152999 | The regulation of telomerase in oncogenesis. |
| Q39241123 | The yeast telomerase RNA, TLC1, participates in two distinct modes of TLC1-TLC1 association processes in vivo |
| Q90744618 | Therapeutic Targets in Telomerase and Telomere Biology of Cancers |
| Q40761812 | Two independent regions of human telomerase reverse transcriptase are important for its oligomerization and telomerase activity |
| Q34050452 | Two purified domains of telomerase reverse transcriptase reconstitute sequence-specific interactions with RNA. |
| Q39390523 | hTERT mutations associated with idiopathic pulmonary fibrosis affect telomerase activity, telomere length, and cell growth by distinct mechanisms |
| Q34625735 | hnRNP A1 associates with telomere ends and stimulates telomerase activity |
| Q24338517 | hnRNP A2, a potential ssDNA/RNA molecular adapter at the telomere |
| Q25257224 | trt-1 is the Caenorhabditis elegans catalytic subunit of telomerase |
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