scholarly article | Q13442814 |
P50 | author | Carol Greider | Q26322 |
P2093 | author name string | Kobayashi R | |
Collins K | |||
P2860 | cites work | The DNA of ciliated protozoa | Q24634620 |
Basic local alignment search tool | Q25938991 | ||
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
A mutant with a defect in telomere elongation leads to senescence in yeast | Q27930429 | ||
Structure and functional properties of human general transcription factor IIE | Q28115411 | ||
Telomerase RNAs of different ciliates have a common secondary structure and a permuted template | Q28240524 | ||
Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II | Q28646845 | ||
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis | Q29614741 | ||
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity | Q29615388 | ||
Telomere length predicts replicative capacity of human fibroblasts | Q29615745 | ||
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements | Q29617964 | ||
TLC1: template RNA component of Saccharomyces cerevisiae telomerase | Q29618197 | ||
Photocrosslinking of 5-Iodouracil-Substituted RNA and DNA to Proteins | Q30464738 | ||
Functional Evidence for an RNA Template in Telomerase | Q33998306 | ||
Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. | Q34989722 | ||
Telomerase activity in human ovarian carcinoma | Q35142569 | ||
Oligonucleotides complementary to the Oxytricha nova telomerase RNA delineate the template domain and uncover a novel mode of primer utilization | Q36671065 | ||
Chromosome first aid. | Q37430022 | ||
Architecture of telomerase RNA. | Q37639292 | ||
Gel shift and UV cross-linking analysis of Tetrahymena telomerase | Q38296586 | ||
Sequence-specific DNA primer effects on telomerase polymerization activity | Q40656443 | ||
Telomeres: no end in sight | Q40763655 | ||
An attempt to unify the structure of polymerases | Q41204694 | ||
A conserved secondary structure for telomerase RNA | Q44060757 | ||
RNA Polymerase Marching Backward | Q46558907 | ||
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs | Q46821624 | ||
The internally located telomeric sequences in the germ-line chromosomes of Tetrahymena are at the ends of transposon-like elements | Q48372823 | ||
Codon usage in Tetrahymena and other ciliates | Q52867193 | ||
Functional reconstitution of wild-type and mutant Tetrahymena telomerase | Q71650294 | ||
Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation | Q72829853 | ||
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 677-686 | |
P577 | publication date | 1995-06-01 | |
P1433 | published in | Cell | Q655814 |
P1476 | title | Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme | |
P478 | volume | 81 |
Q37062421 | A Conserved Telomerase Motif within the Catalytic Domain of Telomerase Reverse Transcriptase Is Specifically Required for Repeat Addition Processivity |
Q36071305 | A functional telomerase RNA swap in vivo reveals the importance of nontemplate RNA domains |
Q28595030 | A mammalian telomerase-associated protein |
Q41138846 | A rapid, useful and quantitative method to measure telomerase activity by hybridization protection assay connected with a telomeric repeat amplification protocol |
Q51762251 | A review of telomere length in sarcopenia and frailty. |
Q40018656 | A single telomerase RNA is sufficient for the synthesis of variable telomeric DNA repeats in ciliates of the genus Paramecium |
Q43636619 | A stem-loop of Tetrahymena telomerase RNA distant from the template potentiates RNA folding and telomerase activity |
Q72036720 | ATP-dependent Processivity of a Telomerase Activity from Saccharomyces cerevisiae |
Q57250868 | Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells |
Q34428321 | Affinity purification of DNA-binding proteins |
Q67213534 | Amplification, increased dosage and in situ expression of the telomerase RNA gene in human cancer |
Q38294059 | An in vitro assay for saccharomyces telomerase requires EST1 |
Q34420492 | Analysis of telomerase in Candida albicans: potential role in telomere end protection |
Q42679147 | Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif |
Q37677320 | Association of the Est1 protein with telomerase activity in yeast |
Q35131769 | Biochemical aspects of telomerase function |
Q40157259 | Biochemical properties of Trypanosoma cruzi telomerase |
Q46980175 | Biological and clinical implications of telomere dysfunction in myeloid malignancies |
Q71738168 | Boundary elements of the Tetrahymena telomerase RNA template and alignment domains |
Q24814974 | CTCF binds the proximal exonic region of hTERT and inhibits its transcription |
Q33925593 | Cell proliferation, carcinogenesis and diverse mechanisms of telomerase regulation |
Q53221552 | Characterization of Trypanosoma cruzi telomerase |
Q36581467 | Characterization of human telomerase complex. |
Q33965566 | Characterization of the interaction between the nuclease and reverse transcriptase activity of the yeast telomerase complex |
Q41125620 | Chromosomal instability and alteration of telomere repeat sequences. |
Q41270223 | Chromosome healing: spontaneous and programmed de novo telomere formation by telomerase |
Q33953553 | Ciliate telomerase biochemistry |
Q34065693 | Comparative Gene Mapping of the Human and Mouse TEP1 Genes, Which Encode One Protein Component of Telomerases |
Q38360360 | Conserved N-terminal motifs of telomerase reverse transcriptase required for ribonucleoprotein assembly in vivo |
Q33973729 | Correlation between expression of human telomerase subunits and telomerase activity in esophageal squamous cell carcinoma |
Q41720377 | DNA dynamics: Different means to a common end? |
Q33886150 | De novo telomere addition by Tetrahymena telomerase in vitro |
Q48599863 | Developmental regulation of telomerase activity in human fetal tissues during gestation |
Q35209661 | Developmentally programmed assembly of higher order telomerase complexes with distinct biochemical and structural properties |
Q33886575 | Developmentally regulated initiation of DNA synthesis by telomerase: evidence for factor-assisted de novo telomere formation |
Q56508142 | Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis |
Q24301904 | Differential regulation of telomerase activity by six telomerase subunits |
Q33890968 | Disease states associated with telomerase deficiency appear earlier in mice with short telomeres |
Q42715561 | Do telomerase antagonists represent a novel anti-cancer strategy? |
Q74457481 | Effect of DNA Secondary Structure on Human Telomerase Activity |
Q54322792 | Eimeria tenella: 14-3-3 protein interacts with telomerase |
Q73149412 | Enzymatic activity of endogenous telomerase associated with intact nuclei from human leukemia CEM cells |
Q27931251 | Est1 has the properties of a single-stranded telomere end-binding protein |
Q30471962 | Euplotes Telomerase: Evidence for Limited Base-Pairing during Primer Elongation and dGTP as an Effector of Translocation |
Q30306373 | Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting |
Q35021955 | Ever shorter telomere 1 ( EST1 )-dependent reverse transcription by Candida telomerase in vitro : Evidence in support of an activating function |
Q58866811 | Evolutionary rates of mammalian telomere-stability genes correlate with karyotype features and female germline expression |
Q55346573 | Expression of human telomerase RNA is an early event of stomach carcinogenesis. |
Q74601071 | Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors |
Q37470406 | Expression of mouse telomerase catalytic subunit in embryos and adult tissues. |
Q33957757 | Expression of mutated Paramecium telomerase RNAs in vivo leads to templating errors that resemble those made by retroviral reverse transcriptase |
Q30779078 | Expression of telomerase subunits in normal and neoplastic prostate epithelial cells isolated by laser capture microdissection |
Q33772647 | Flexible Positioning of the Telomerase-Associated Nuclease Leads to Preferential Elimination of Nontelomeric DNA |
Q91742198 | Functional Proteomics of Nuclear Proteins in Tetrahymena thermophila: A Review |
Q38296299 | Functional analysis of conserved residues in the putative "finger" domain of telomerase reverse transcriptase |
Q74549782 | Functional analysis of the C-terminal extension of telomerase reverse transcriptase. A putative "thumb" domain |
Q33969441 | Functional multimerization of the human telomerase reverse transcriptase |
Q35194966 | Functionally interacting telomerase RNAs in the yeast telomerase complex |
Q77935987 | Genes involved in the control of cellular proliferative potential |
Q40953506 | Genomic organization and promoter characterization of the gene encoding the human telomerase reverse transcriptase (hTERT). |
Q40882874 | Holoenzyme proteins required for the physiological assembly and activity of telomerase |
Q24533247 | Human telomerase and its regulation |
Q24604009 | Human telomerase contains evolutionarily conserved catalytic and structural subunits |
Q77959517 | Human telomerase reverse transcriptase as a critical determinant of telomerase activity in normal and malignant endometrial tissues |
Q36786230 | ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor |
Q39721592 | Identification and characterization of a telomerase activity from Schizosaccharomyces pombe |
Q38342698 | Identification of Determinants for Inhibitor Binding within the RNA Active Site of Human Telomerase Using PNA Scanning |
Q63384208 | Identification of Functional Domains and Dominant Negative Mutations in Vertebrate Telomerase RNA Using anin VivoReconstitution System |
Q39575704 | Identification of Kluyveromyces lactis Telomerase: Discontinuous Synthesis along the 30-Nucleotide-Long Templating Domain |
Q33964637 | Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase |
Q24548517 | Identification of two RNA-binding proteins associated with human telomerase RNA |
Q78654076 | Implication of the exon region in the regulation of the human telomerase reverse transcriptase gene promoter |
Q40422066 | In vivo synthesis of nano-selenium by Tetrahymena thermophila SB210. |
Q28366118 | Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. |
Q47960865 | Inhibition of human telomerase activity by peptide nucleic acids |
Q60589823 | Inhibition of telomerase activity by a cell-penetrating peptide nucleic acid construct in human melanoma cells |
Q35193095 | Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates |
Q38502576 | Interaction of the Nuclear Matrix-associated Region (MAR)-Binding Proteins, SATB1 and CDP/Cux, with a MAR Element (L2a) in an Upstream Regulatory Region of the Mouse CD8a Gene |
Q38311992 | Interference footprinting analysis of telomerase elongation complexes |
Q41610038 | Mammalian Telomerase: Catalytic Subunit and Knockout Mice |
Q48028040 | Mapping of the Gene for Rat Telomerase Protein Component 1(Tlp1) to Chromosome 15 |
Q41441652 | Mechanisms of cellular senescence |
Q34081958 | Microenvironmental regulation of telomerase isoforms in human embryonic stem cells |
Q24545497 | Mini- and microsatellites |
Q24537660 | Minimum length requirement of the alignment domain of human telomerase RNA to sustain catalytic activity in vitro |
Q42609119 | Molecular cloning and characterization of AtTERT, a telomerase reverse transcriptase homolog in Arabidopsis thaliana |
Q28118564 | Molecular interactions between telomerase and the tumor suppressor protein p53 in vitro |
Q41730873 | Mouse models for the study of telomerase. |
Q34655881 | Mutational analysis of the Tetrahymena telomerase RNA: identification of residues affecting telomerase activity in vitro |
Q38338378 | Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer |
Q39724301 | One-step affinity purification protocol for human telomerase |
Q42576145 | Organization of chromosome ends in Ustilago maydis. RecQ-like helicase motifs at telomeric regions. |
Q36835046 | Permanent embryo arrest: molecular and cellular concepts |
Q34595148 | Physical Activity and Telomere Biology: Exploring the Link with Aging-Related Disease Prevention |
Q24550780 | Polymerization defects within human telomerase are distinct from telomerase RNA and TEP1 binding |
Q73876649 | Possible mechanisms for the regulation of telomere length |
Q40791502 | Preparation of monoclonal antibodies against human telomerase |
Q36560631 | Processing of nontelomeric 3' ends by telomerase: default template alignment and endonucleolytic cleavage |
Q34790751 | Prospects for anti-neoplastic therapies based on telomere biology |
Q73456230 | Protein phosphatase 2A inhibits nuclear telomerase activity in human breast cancer cells |
Q30469368 | Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang |
Q47848808 | Putative telomerase catalytic subunits from Giardia lamblia and Caenorhabditis elegans |
Q35912728 | Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. |
Q28116966 | Reconstitution of human telomerase activity in vitro |
Q24313396 | Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT |
Q77293489 | Regulation of catalytic activity and processivity of human telomerase |
Q34675873 | Reiterative dG addition by Euplotes crassus telomerase during extension of non-telomeric DNA |
Q34451265 | Relics from the RNA World |
Q29618392 | Reverse transcriptase motifs in the catalytic subunit of telomerase |
Q37380017 | Reversible immortalization of mammalian cells mediated by retroviral transfer and site-specific recombination |
Q30471858 | Reversing Time: Origin of Telomerase |
Q41701216 | Review Chromosome healing, telomere capture and mechanisms of radiation-induced chromosome breakage |
Q34130110 | Ribonucleoprotein multimers and their functions |
Q35956258 | Role of the casein kinase I isoform, Hrr25, and the cell cycle-regulatory transcription factor, SBF, in the transcriptional response to DNA damage in Saccharomyces cerevisiae |
Q27931258 | Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. |
Q38324157 | Sequence-specific and conformation-dependent binding of yeast telomerase RNA to single-stranded telomeric DNA |
Q34659594 | Species-specific and sequence-specific recognition of the dG-rich strand of telomeres by yeast telomerase |
Q36556655 | Specific RNA residue interactions required for enzymatic functions of Tetrahymena telomerase |
Q35210631 | Specific telomerase RNA residues distant from the template are essential for telomerase function |
Q41066960 | Structure and function of telomerase |
Q40955340 | Structure, function, and replication of Saccharomyces cerevisiae telomeres |
Q37472153 | Structure-function relationships in telomerase genes. |
Q33792301 | Studies of the molecular mechanisms in the regulation of telomerase activity |
Q28564535 | TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats family |
Q41071112 | Telomerase Activity in Human Leukemic Cell Lines Is Inhibited by Antisense Pentadecadeoxynucleotides Targeted against c-myc mRNA |
Q29615387 | Telomerase Catalytic Subunit Homologs from Fission Yeast and Human |
Q35203518 | Telomerase RNA function in recombinant Tetrahymena telomerase |
Q40915193 | Telomerase activation and cancer. |
Q35763644 | Telomerase activation in cervical cancer. |
Q48905543 | Telomerase activity and telomere detection during early bovine development |
Q40977667 | Telomerase activity does not always imply telomere maintenance |
Q73016390 | Telomerase activity in bladder carcinoma and its implication for noninvasive diagnosis by detection of exfoliated cancer cells in urine |
Q77578762 | Telomerase activity in gestational trophoblastic disease and placental tissue from early and late human pregnancies |
Q77317980 | Telomerase activity in ‘immortal’ fish1 |
Q77729120 | Telomerase activity, MIB-1, PCNA, HPV 16 and p53 as diagnostic markers for cervical intraepithelial neoplasia |
Q57129041 | Telomerase and cancer |
Q30472155 | Telomerase and chromosome end maintenance. |
Q41560700 | Telomerase and telomere-binding proteins: controlling the endgame. |
Q30471909 | Telomerase and the Chromosome end Replication Problem |
Q36068547 | Telomerase catalysis: A phylogenetically conserved reverse transcriptase |
Q33533965 | Telomerase enzyme activation and human cell immortalization |
Q77408401 | Telomerase from Saccharomyces cerevisiae contains several protein subunits and may have different activities depending on the protein content |
Q46450385 | Telomerase in cancer: clinical applications |
Q32182322 | Telomerase in gynecologic cancers |
Q34068018 | Telomerase is controlled by protein kinase Calpha in human breast cancer cells |
Q38328772 | Telomerase protein rather than its RNA is the target of phosphorothioate-modified oligonucleotides |
Q30472352 | Telomerase reverse transcriptase genes identified in Tetrahymena thermophila and Oxytricha trifallax |
Q77892451 | Telomerase, Ku, and telomeric silencing in Saccharomyces cerevisiae |
Q34148457 | Telomerase, immortality and cancer |
Q28140790 | Telomerase-associated protein TEP1 is not essential for telomerase activity or telomere length maintenance in vivo |
Q80600068 | Telomerase: a dimeric ménage à trois |
Q41239266 | Telomerase: anti-cancer target or just a fascinating enzyme? |
Q33885734 | Telomerase: therapeutic potential in cancer |
Q77331385 | Telomere Structure, Replication and Length Maintenance |
Q40893289 | Telomere crisis in leukemia |
Q38127519 | Telomere length and telomerase activity during oocyte maturation and early embryo development in mammalian species |
Q48589695 | Telomere length and telomerase activity in bovine pre-implantation embryos in vitro |
Q36255827 | Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice |
Q28290143 | Telomere length regulation |
Q33540084 | Telomere maintenance mechanisms and cellular immortalization. |
Q34293590 | Telomere maintenance mechanisms as a target for drug development |
Q24598974 | Telomere shortening and apoptosis in telomerase-inhibited human tumor cells |
Q33890481 | Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube |
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