Est1 has the properties of a single-stranded telomere end-binding protein

scientific article

Est1 has the properties of a single-stranded telomere end-binding protein is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GAD.10.24.3094
P3181OpenCitations bibliographic resource ID3371737
P698PubMed publication ID8985179
P5875ResearchGate publication ID14223307

P2093author name stringV Lundblad
D K Morris
V Virta-Pearlman
P2860cites workRunaway telomere elongation caused by telomerase RNA gene mutationsQ46144742
Telomerase in yeastQ46265180
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAsQ46821624
Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzymeQ48072977
Telomere length regulationQ28290143
Identification of a specific telomere terminal transferase activity in Tetrahymena extractsQ28306745
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesisQ29614741
Functional Evidence for an RNA Template in TelomeraseQ33998306
DNA sequences of telomeres maintained in yeastQ34255911
DNA bound by the Oxytricha telomere protein is accessible to telomerase and other DNA polymerasesQ34970459
Identification of a nonprocessive telomerase activity from mouse cellsQ36110288
Telomerase activity in germline and embryonic cells of Xenopus.Q37634408
Gel shift and UV cross-linking analysis of Tetrahymena telomeraseQ38296586
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectEst1p YLR233CQ27547434
P304page(s)3094-104
P577publication date1996-12-15
P1433published inGenes & DevelopmentQ1524533
P1476titleEst1 has the properties of a single-stranded telomere end-binding protein
P478volume10

Reverse relations

cites work (P2860)
Q30754050A Trypanosoma brucei Protein Complex That Binds G-overhangs and Co-purifies with Telomerase Activity
Q39646669A central role for Plasmodium falciparum subtelomeric regions in spatial positioning and telomere length regulation
Q28116014A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed
Q31030721A novel allele of fission yeast rad11 that causes defects in DNA repair and telomere length regulation.
Q34420492Analysis of telomerase in Candida albicans: potential role in telomere end protection
Q35131769Biochemical aspects of telomerase function
Q27933016Biogenesis of yeast telomerase depends on the importin mtr10
Q27933598Cdc13 cooperates with the yeast Ku proteins and Stn1 to regulate telomerase recruitment
Q37830721Cell-cycle-dependent telomere elongation by telomerase in budding yeast
Q27930866Characterization of recombinant Saccharomyces cerevisiae telomerase core enzyme purified from yeast
Q27937911Characterization of the intramolecular G‐quadruplex promoting activity of Est1
Q36392152Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae
Q36942197Coordinate Regulation of G- and C Strand Length during New Telomere Synthesis
Q27766424Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA
Q27618173Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA
Q34614236Dynamics of telomeric DNA turnover in yeast
Q30304451Essential functions of amino-terminal domains in the yeast telomerase catalytic subunit revealed by selection for viable mutants
Q27932081Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction
Q41787808Est1 protects telomeres and inhibits subtelomeric y'-element recombination
Q30306373Euplotes telomerase contains an La motif protein produced by apparent translational frameshifting
Q35021955Ever shorter telomere 1 ( EST1 )-dependent reverse transcription by Candida telomerase in vitro : Evidence in support of an activating function
Q36154367Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end.
Q24606549Finding the end: recruitment of telomerase to telomeres
Q24619822Functional Analysis of the Single Est1/Ebs1 Homologue in Kluyveromyces lactis Reveals Roles in both Telomere Maintenance and Rapamycin Resistance
Q74549782Functional analysis of the C-terminal extension of telomerase reverse transcriptase. A putative "thumb" domain
Q24299999Functional conservation of the telomerase protein Est1p in humans
Q35194966Functionally interacting telomerase RNAs in the yeast telomerase complex
Q33957324Gbp1p, a protein with RNA recognition motifs, binds single-stranded telomeric DNA and changes its binding specificity upon dimerization
Q34607461Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+).
Q35611361Getting to the end: telomerase access in yeast and humans
Q38312541Heterogeneous nuclear ribonucleoprotein A1 and UP1 protect mammalian telomeric repeats and modulate telomere replication in vitro
Q33964637Identification of functionally important domains in the N-terminal region of telomerase reverse transcriptase
Q39454508In vitro properties of the conserved mammalian protein hnRNP D suggest a role in telomere maintenance
Q37069656Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control
Q33196380Interaction of an Arabidopsis RNA-binding protein with plant single-stranded telomeric DNA modulates telomerase activity
Q35193095Interaction of recombinant Tetrahymena telomerase proteins p80 and p95 with telomerase RNA and telomeric DNA substrates
Q38321503Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae
Q36245192Making the most of a little: dosage effects in eukaryotic telomere length maintenance
Q40780077Mixed Integer Linear Programming based machine learning approach identifies regulators of telomerase in yeast
Q27930756Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro
Q35132538Molecular manifestations and molecular determinants of telomere capping
Q40207099Mutual dependence of Candida albicans Est1p and Est3p in telomerase assembly and activation
Q38338378Negative regulation of yeast telomerase activity through an interaction with an upstream region of the DNA primer
Q27932588PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase
Q27936627Programmed translational frameshifting in a gene required for yeast telomere replication
Q41855271Progressive cis-inhibition of telomerase upon telomere elongation.
Q24801692Progressive rearrangement of telomeric sequences added to both the ITR ends of the yeast linear pGKL plasmid
Q41792156Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae
Q28117179Protein RNA and protein protein interactions mediate association of human EST1A/SMG6 with telomerase
Q47895627Proteins that bind to double-stranded regions of telomeric DNA.
Q27938540RNase III-dependent regulation of yeast telomerase
Q37235381Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13.
Q27935645Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex
Q36573452Reprogramming of Telomerase by Expression of Mutant Telomerase RNA Template in Human Cells Leads to Altered Telomeres That Correlate with Reduced Cell Viability
Q24295213SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway
Q25255779Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo
Q28144506Saccharomyces cerevisiae telomerase is an Sm small nuclear ribonucleoprotein particle
Q27931665Selection of novel, specific single-stranded DNA sequences by Flp, a duplex-specific DNA binding protein
Q27932748Sir Proteins, Rif Proteins, and Cdc13p Bind Saccharomyces Telomeres In Vivo
Q34659594Species-specific and sequence-specific recognition of the dG-rich strand of telomeres by yeast telomerase
Q38301809Specific binding of single-stranded telomeric DNA by Cdc13p of Saccharomyces cerevisiae
Q36183576Stiffened yeast telomerase RNA supports RNP function in vitro and in vivo
Q33962968Telomerase RNA template mutations reveal sequence-specific requirements for the activation and repression of telomerase action at telomeres
Q57205588Telomerase activity and telomere length in human hepatocellular carcinoma
Q30472155Telomerase and chromosome end maintenance.
Q41560700Telomerase and telomere-binding proteins: controlling the endgame.
Q30304123Telomerase and the maintenance of chromosome ends
Q36068547Telomerase catalysis: A phylogenetically conserved reverse transcriptase
Q33616690Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres
Q64988940Telomerase-mediated telomere addition in vivo requires DNA primase and DNA polymerases alpha and delta.
Q37854760Telomerase: Structure, functions, and activity regulation
Q33536623Telomerases
Q77331385Telomere Structure, Replication and Length Maintenance
Q41035726Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase
Q35291052Telomere fusions caused by mutating the terminal region of telomeric DNA
Q73216287Telomere maintenance in fission yeast requires an Est1 ortholog
Q35142887Telomere replication: an Est fest
Q33855751Telomere-binding and Stn1p-interacting activities are required for the essential function of Saccharomyces cerevisiae Cdc13p
Q33632382Telomeres and telomerase: broad effects on cell growth
Q34090772Telomeres and their control
Q74325473Telomeric sequence diversity within the genus Saccharomyces
Q27938764Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13
Q42566913Tetrahymena Mutants With Short Telomeres
Q39574489The C Terminus of the Major Yeast Telomere Binding Protein Rap1p Enhances Telomere Formation
Q34616372The Est1 subunit of Saccharomyces cerevisiae telomerase makes multiple contributions to telomere length maintenance
Q33786914The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA
Q41730845The Role of the EST Genes in Yeast Telomere Replication
Q27931011The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein
Q28975759The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis
Q27933409The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein
Q36558592The catalytic subunit of yeast telomerase
Q37394791The conserved Est1 protein stimulates telomerase DNA extension activity
Q33961700The function of DNA polymerase alpha at telomeric G tails is important for telomere homeostasis
Q80818316The identification of telomerase subunits: catalysing telomere research
Q34016553The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres
Q35179269The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation.
Q35651048The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro
Q27930962The yeast telomere length regulator TEL2 encodes a protein that binds to telomeric DNA
Q30471100Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity
Q36256436Uncapping and deregulation of telomeres lead to detrimental cellular consequences in yeast
Q47350265Using Separation-of-Function Mutagenesis To Define the Full Spectrum of Activities Performed by the Est1 Telomerase Subunit in Vivo
Q27933320Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation
Q33938937hnRNP A1 may interact simultaneously with telomeric DNA and the human telomerase RNA in vitro

Search more.