review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1007/S10577-005-0994-5 |
P698 | PubMed publication ID | 16132814 |
P2093 | author name string | Lea Harrington | |
P2860 | cites work | Ku binds telomeric DNA in vitro | Q22010395 |
Ku is associated with the telomere in mammals | Q22010717 | ||
Rap1 affects the length and heterogeneity of human telomeres | Q24298023 | ||
Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase | Q24299861 | ||
Wild-derived inbred mouse strains have short telomeres | Q24528999 | ||
Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae | Q24532215 | ||
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres | Q24536297 | ||
Generation of telomere-length heterogeneity in Saccharomyces cerevisiae | Q24655918 | ||
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. | Q27640301 | ||
A mutant with a defect in telomere elongation leads to senescence in yeast | Q27930429 | ||
The ctf13-30/CTF13 genomic haploinsufficiency modifier screen identifies the yeast chromatin remodeling complex RSC, which is required for the establishment of sister chromatid cohesion | Q27930793 | ||
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein | Q27931011 | ||
Est1 has the properties of a single-stranded telomere end-binding protein | Q27931251 | ||
Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. | Q27931258 | ||
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. | Q27932204 | ||
A protein-counting mechanism for telomere length regulation in yeast. | Q27932745 | ||
Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo | Q36700876 | ||
Telomerase expression in chickens: constitutive activity in somatic tissues and down-regulation in culture | Q36754544 | ||
Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA | Q36774602 | ||
Varying the number of telomere-bound proteins does not alter telomere length in tel1Delta cells. | Q36780361 | ||
Does a sentinel or a subset of short telomeres determine replicative senescence? | Q37031784 | ||
End Resection Initiates Genomic Instability in the Absence of Telomerase | Q37062471 | ||
Yeast genome-wide drug-induced haploinsufficiency screen to determine drug mode of action | Q37358045 | ||
Expression of mouse telomerase catalytic subunit in embryos and adult tissues. | Q37470406 | ||
Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice | Q37646957 | ||
Association of the Est1 protein with telomerase activity in yeast | Q37677320 | ||
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice. | Q38331074 | ||
A bulged stem tethers Est1p to telomerase RNA in budding yeast | Q27933008 | ||
The Est3 protein is a subunit of yeast telomerase | Q27933462 | ||
Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events | Q27936385 | ||
Human Ku70/80 associates physically with telomerase through interaction with hTERT | Q28115815 | ||
Homologous recombination generates T-loop-sized deletions at human telomeres | Q28116970 | ||
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation | Q28145356 | ||
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes. | Q28366118 | ||
DNA damage foci at dysfunctional telomeres | Q29614811 | ||
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
Switching and signaling at the telomere | Q29615653 | ||
A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
Regulation of telomerase by telomeric proteins | Q29616133 | ||
An alternative pathway for yeast telomere maintenance rescues est1- senescence | Q29616135 | ||
TLC1: template RNA component of Saccharomyces cerevisiae telomerase | Q29618197 | ||
Reverse transcriptase motifs in the catalytic subunit of telomerase | Q29618392 | ||
Essential role of mouse telomerase in highly proliferative organs | Q29620451 | ||
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity | Q30471100 | ||
Living with genome instability: plant responses to telomere dysfunction | Q33335422 | ||
The murine gene p27Kip1 is haplo-insufficient for tumour suppression | Q33574523 | ||
Telomerase-dependent repeat divergence at the 3' ends of yeast telomeres | Q33616690 | ||
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang | Q33757028 | ||
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. | Q33757674 | ||
The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA | Q33786914 | ||
A critical role for telomeres in suppressing and facilitating carcinogenesis | Q33840458 | ||
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse | Q33862948 | ||
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis | Q33862956 | ||
Ku86 is essential in human somatic cells | Q33894543 | ||
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice | Q33914498 | ||
Telomere dysfunction triggers developmentally regulated germ cell apoptosis. | Q33937428 | ||
Repair of chromosome ends after telomere loss in Saccharomyces | Q33948830 | ||
Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae | Q33948868 | ||
Unlinked noncomplementation: isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae | Q33954146 | ||
Alternative lengthening of telomeres: dangerous road less travelled | Q33966399 | ||
The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang. | Q33968202 | ||
Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae | Q34012288 | ||
Haploinsufficiency of mTR results in defects in telomere elongation | Q34019216 | ||
The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activities | Q38335557 | ||
The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. | Q39444293 | ||
The C terminus of the major yeast telomere binding protein Rap1p enhances telomere formation | Q39574489 | ||
Different telomere damage signaling pathways in human and mouse cells | Q39647901 | ||
Haploinsufficiency of p18(INK4c) sensitizes mice to carcinogen-induced tumorigenesis | Q39700541 | ||
The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae. | Q39753325 | ||
Role of human Ku86 in telomere length maintenance and telomere capping | Q40502741 | ||
Stochastic variation in telomere shortening rate causes heterogeneity of human fibroblast replicative life span | Q40590057 | ||
Identification of telomere-dependent "senescence-like" arrest in mouse embryonic fibroblasts | Q40730211 | ||
Telomeres and senescence: the history, the experiment, the future | Q40863958 | ||
Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase | Q41035726 | ||
Rap1p and telomere length regulation in yeast. | Q41730851 | ||
Progressive cis-inhibition of telomerase upon telomere elongation. | Q41855271 | ||
Two recessive suppressors of Saccharomyces cerevisiae cho1 that are unlinked but fall in the same complementation group | Q42052720 | ||
The zebrafish as a vertebrate model of functional aging and very gradual senescence | Q44509497 | ||
Differential impact of telomere dysfunction on initiation and progression of hepatocellular carcinoma. | Q44564108 | ||
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity. | Q44762653 | ||
Involvement of mammalian Mus81 in genome integrity and tumor suppression | Q47323217 | ||
A novel mechanism for telomere size control in Saccharomyces cerevisiae | Q47331172 | ||
Ndj1p-dependent epigenetic resetting of telomere size in yeast meiosis | Q47393050 | ||
Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states. | Q47699338 | ||
Length control of human telomeres. | Q47997254 | ||
Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells | Q48560666 | ||
Regulation of tubulin gene expression during embryogenesis in Drosophila melanogaster. | Q52527303 | ||
Telomerase maintains telomere structure in normal human cells. | Q52551445 | ||
Combined haploinsufficiency for ATM and RAD9 as a factor in cell transformation, apoptosis, and DNA lesion repair dynamics. | Q53360868 | ||
Telomere dysfunction and the initiation of genome instability. | Q55036686 | ||
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability | Q56508014 | ||
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice | Q56508064 | ||
Taking the measure | Q59043529 | ||
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing | Q59086518 | ||
Association between aplastic anaemia and mutations in telomerase RNA | Q59463050 | ||
Telomerase levels control the lifespan of human T lymphocytes | Q60628793 | ||
Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis | Q61872130 | ||
Est1 and Cdc13 as comediators of telomerase access | Q73042124 | ||
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation | Q73322990 | ||
Synthetic dosage lethality | Q74321407 | ||
Telomerase activity in candidate stem cells from fetal liver and adult bone marrow | Q74477777 | ||
Est1p as a cell cycle-regulated activator of telomere-bound telomerase | Q74593218 | ||
Enhanced tumor formation in mice heterozygous for Blm mutation | Q74813290 | ||
Exploring the etiology of haploinsufficiency | Q77614631 | ||
Deficiency of Retinoblastoma gene in mouse embryonic stem cells leads to genetic instability | Q78019639 | ||
Nonlinear effects in macromolecular assembly and dosage sensitivity | Q78578422 | ||
Msh2 deficiency increases the mutation frequency in all parts of the mouse colon | Q78681880 | ||
The yeast VPS genes affect telomere length regulation | Q81024710 | ||
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert. | Q34019245 | ||
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae | Q34035073 | ||
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression | Q34166733 | ||
Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 | Q34181022 | ||
Dosage sensitivity and the evolution of gene families in yeast | Q34213245 | ||
Developmental and tissue-specific regulation of mouse telomerase and telomere length | Q34265760 | ||
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia | Q34409487 | ||
A molecular switch underlies a human telomerase disease | Q34430499 | ||
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita | Q34514264 | ||
A genome-wide screen for Saccharomyces cerevisiae deletion mutants that affect telomere length | Q34514337 | ||
Telomere maintenance without telomerase | Q34535615 | ||
A model for heterogeneous nuclear ribonucleoproteins in telomere and telomerase regulation | Q34535640 | ||
Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis. | Q34543987 | ||
Mechanisms of haploinsufficiency revealed by genome-wide profiling in yeast | Q34572690 | ||
Dynamics of telomeric DNA turnover in yeast | Q34614236 | ||
The Est1 subunit of Saccharomyces cerevisiae telomerase makes multiple contributions to telomere length maintenance | Q34616372 | ||
Telomerase-independent proliferation is influenced by cell type in Saccharomyces cerevisiae | Q34617934 | ||
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. | Q34724924 | ||
Expanded repeat sequences and disease | Q34795207 | ||
Short telomeres induce a DNA damage response in Saccharomyces cerevisiae | Q34813172 | ||
Alternative lengthening of telomeres, telomerase, and cancer. | Q35131772 | ||
Telomere repeat binding factors: keeping the ends in check | Q35131785 | ||
Telomere structure, function and maintenance in Arabidopsis | Q35137119 | ||
Ku acts in a unique way at the mammalian telomere to prevent end joining | Q35207184 | ||
Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways | Q35218053 | ||
Which end: dissecting Ku's function at telomeres and double-strand breaks: Figure 1 | Q35549049 | ||
Chemogenomic profiling: identifying the functional interactions of small molecules in yeast | Q35554300 | ||
Retrotransposons provide an evolutionarily robust non-telomerase mechanism to maintain telomeres | Q35582993 | ||
Alternatives to telomerase: keeping linear chromosomes via telomeric circles | Q35785917 | ||
Telomerase activity, cell proliferation, and cancer | Q36166271 | ||
Telomere cap components influence the rate of senescence in telomerase-deficient yeast cells | Q36222630 | ||
Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs | Q36322778 | ||
Evidence for Msh2 haploinsufficiency in mice revealed by MNU-induced sister-chromatid exchange analysis | Q36691964 | ||
P433 | issue | 5 | |
P921 | main subject | telomere length | Q59658244 |
P304 | page(s) | 493-504 | |
P577 | publication date | 2005-01-01 | |
P1433 | published in | Chromosome Research | Q15765850 |
P1476 | title | Making the most of a little: dosage effects in eukaryotic telomere length maintenance | |
P478 | volume | 13 |
Q33315749 | Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance. |
Q54657596 | Leishmania amazonensis: Partial purification and study of the biochemical properties of the telomerase reverse transcriptase activity from promastigote-stage |
Q30441223 | Low abundance of telomerase in yeast: implications for telomerase haploinsufficiency |
Q39906810 | No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells |
Q40001546 | Regulation of telomeric repeat binding factor 1 binding to telomeres by casein kinase 2-mediated phosphorylation |
Q41967731 | Telomerase RNA biogenesis involves sequential binding by Sm and Lsm complexes |
Q37950142 | Telomerase regulation |
Q37002134 | Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells |
Q34410927 | Telomere length homeostasis requires that telomerase levels are limiting |
Q33933472 | Telomere length is inherited with resetting of the telomere set-point. |
Q37136795 | Ubiquitin Ligase RLIM Modulates Telomere Length Homeostasis through a Proteolysis of TRF1. |
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