| scholarly article | Q13442814 |
| P50 | author | Maria A Blasco | Q54086437 |
| P2093 | author name string | E Samper | |
| F A Goytisolo | |||
| G E Taccioli | |||
| S Edmonson | |||
| P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
| Ku binds telomeric DNA in vitro | Q22010395 | ||
| Ku is associated with the telomere in mammals | Q22010717 | ||
| Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres | Q22254585 | ||
| Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells | Q24320116 | ||
| DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product | Q24337388 | ||
| Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing | Q24533190 | ||
| Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast | Q27936427 | ||
| TRF2 Protects Human Telomeres from End-to-End Fusions | Q28111898 | ||
| Mouse Lymphoma Cells with Different Radiosensitivities | Q59086828 | ||
| Elongated Telomeres inscidMice | Q61872134 | ||
| Telomeres and telomerase | Q63384209 | ||
| TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1 | Q71709839 | ||
| Yeast Ku as a regulator of chromosomal DNA end structure | Q74490854 | ||
| A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombination | Q77398644 | ||
| MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaks | Q28137625 | ||
| Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development | Q28143170 | ||
| Deletion of Ku86 causes early onset of senescence in mice | Q28144342 | ||
| Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination | Q28243620 | ||
| The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination | Q28272412 | ||
| DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect | Q28307262 | ||
| The DNA-dependent protein kinase | Q28373950 | ||
| Targeted disruption of the catalytic subunit of the DNA-PK gene in mice confers severe combined immunodeficiency and radiosensitivity | Q28506163 | ||
| Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
| Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity | Q29615388 | ||
| Structure and function of telomeres | Q29615759 | ||
| Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang | Q33757028 | ||
| Disease states associated with telomerase deficiency appear earlier in mice with short telomeres | Q33890968 | ||
| Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice | Q33914498 | ||
| Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance | Q34411525 | ||
| Ku acts in a unique way at the mammalian telomere to prevent end joining | Q35207184 | ||
| Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice | Q36044979 | ||
| Ku70 is required for DNA repair but not for T cell antigen receptor gene recombination In vivo | Q36380622 | ||
| Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes | Q36562716 | ||
| Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats | Q36657077 | ||
| DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes | Q36775252 | ||
| Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse | Q36820879 | ||
| Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity | Q36973681 | ||
| Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates | Q38354165 | ||
| Requirement for Ku80 in growth and immunoglobulin V(D)J recombination | Q38354221 | ||
| Heterogeneity in telomere length of human chromosomes. | Q39426746 | ||
| G-strand overhangs on telomeres in telomerase-deficient mouse cells | Q39729234 | ||
| Impaired germinal center reaction in mice with short telomeres. | Q40387000 | ||
| DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus | Q40892156 | ||
| Ku70: a candidate tumor suppressor gene for murine T cell lymphoma | Q41017020 | ||
| Telomerase and cancer: revisiting the telomere hypothesis | Q41211805 | ||
| Telomere maintenance is dependent on activities required for end repair of double-strand breaks | Q47946099 | ||
| Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres | Q47946111 | ||
| Human DNA-activated protein kinase (DNA-PK) is homologous to phosphatidylinositol kinases | Q48069226 | ||
| TEL1, a gene involved in controlling telomere length in S. cerevisiae, is homologous to the human ataxia telangiectasia gene | Q48070727 | ||
| Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. | Q55067752 | ||
| Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis | Q56508142 | ||
| Accelerated telomere shortening in ataxia telangiectasia | Q57017468 | ||
| P433 | issue | 11 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | telomere length | Q59658244 |
| P304 | page(s) | 3642-3651 | |
| P577 | publication date | 2001-06-01 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang | |
| P478 | volume | 21 |
| Q35283684 | 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition |
| Q28116014 | A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed |
| Q63384201 | A role for the Rb family of proteins in controlling telomere length |
| Q34535665 | ATM function and telomere stability |
| Q33717036 | ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase |
| Q37033635 | Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability |
| Q35050968 | Assessment of telomere length and factors that contribute to its stability |
| Q37067030 | Association between the XRCC6 Promoter rs2267437 polymorphism and cancer risk: evidence based on the current literature |
| Q44790377 | Brief report: impaired cell reprogramming in nonhomologous end joining deficient cells. |
| Q54335200 | Changes in telomere length distribution in low-dose X-ray-irradiated human umbilical vein endothelial cells. |
| Q34282271 | Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells |
| Q42072170 | Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways |
| Q33965717 | Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops |
| Q33990112 | Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis. |
| Q34775818 | DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. |
| Q43109421 | DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. |
| Q34098695 | DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. |
| Q28509254 | DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 |
| Q36245188 | DNA repair and recombination functions in Arabidopsis telomere maintenance |
| Q36509842 | DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination |
| Q92977240 | DNA-PKcs modulates progenitor cell proliferation and fibroblast senescence in idiopathic pulmonary fibrosis |
| Q35638872 | DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication |
| Q28511262 | DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse |
| Q92980463 | DNA-dependent protein kinase in telomere maintenance and protection |
| Q28266367 | DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase |
| Q28513655 | Defective DNA repair and increased genomic instability in Artemis-deficient murine cells |
| Q44696976 | Different DNA-PKcs functions in the repair of radiation-induced and spontaneous DSBs within interstitial telomeric sequences. |
| Q40503154 | Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines. |
| Q33888481 | Effects of double-strand break repair proteins on vertebrate telomere structure |
| Q36936810 | End joining at Caenorhabditis elegans telomeres |
| Q40161913 | Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres |
| Q35871249 | Expression of human protection of telomere 1 correlates with telomere length and radiosensitivity in the human laryngeal cancer Hep-2 cell line |
| Q34369713 | Functional interaction between DNA-PKcs and telomerase in telomere length maintenance |
| Q36232699 | Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2. |
| Q46223955 | Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer |
| Q42112893 | Gene amplification in human cells knocked down for RAD54 |
| Q45872420 | Gene therapy with the TRF1 telomere gene rescues decreased TRF1 levels with aging and prolongs mouse health span |
| Q37021560 | HTLV-1 Tax oncoprotein subverts the cellular DNA damage response via binding to DNA-dependent protein kinase |
| Q24299861 | Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase |
| Q34142564 | IL-7Rα deficiency in p53null mice exacerbates thymocyte telomere erosion and lymphomagenesis |
| Q35710278 | Identification of telomere dysfunction in Friedreich ataxia |
| Q36322778 | Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs |
| Q39686949 | Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant. |
| Q35632849 | Indecent exposure: when telomeres become uncapped |
| Q37289254 | Inhibition of Snail1-DNA-PKcs protein-protein interface sensitizes cancer cells and inhibits tumor metastasis |
| Q26771437 | Insertion of Retrotransposons at Chromosome Ends: Adaptive Response to Chromosome Maintenance |
| Q34468156 | LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines. |
| Q92046278 | Long interspersed element-1 ribonucleoprotein particles protect telomeric ends in alternative lengthening of telomeres dependent cells |
| Q36245192 | Making the most of a little: dosage effects in eukaryotic telomere length maintenance |
| Q24536297 | Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres |
| Q35569699 | Mammalian telomeres and telomerase: why they matter for cancer and aging |
| Q34535647 | Many ways to telomere dysfunction: in vivo studies using mouse models |
| Q44200256 | Massive telomere loss is an early event of DNA damage-induced apoptosis |
| Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
| Q44626076 | Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts |
| Q35003946 | Mouse models to study the role of telomeres in cancer, aging and DNA repair |
| Q28506028 | Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages |
| Q39137894 | Mutations to Ku reveal differences in human somatic cell lines |
| Q36377992 | Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability |
| Q44388715 | Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response |
| Q36748114 | Nuclear factor 45 (NF45) is a regulatory subunit of complexes with NF90/110 involved in mitotic control |
| Q29618748 | Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts |
| Q36454901 | PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis. |
| Q35653296 | Predictive role of XRCC5/XRCC6 genotypes in digestive system cancers. |
| Q29618391 | Protection of mammalian telomeres |
| Q34430830 | Putting the stress on senescence |
| Q39503969 | Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. |
| Q28214575 | Recombinational DNA repair and human disease |
| Q34181022 | Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 |
| Q40324038 | Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint |
| Q33757674 | Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. |
| Q37354009 | Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain. |
| Q35169573 | Role of mammalian Rad54 in telomere length maintenance |
| Q37869121 | Role of the XRCC5/XRCC6 dimer in carcinogenesis and pharmacogenomics. |
| Q24537136 | Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice |
| Q36948528 | Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection |
| Q34478480 | Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints |
| Q33878468 | TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends |
| Q52551445 | Telomerase maintains telomere structure in normal human cells. |
| Q36103575 | Telomere biology: integrating chromosomal end protection with DNA damage response |
| Q36676871 | Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence |
| Q30953207 | Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein |
| Q24338140 | Telomere maintenance requires the RAD51D recombination/repair protein |
| Q35131785 | Telomere repeat binding factors: keeping the ends in check |
| Q35062454 | Telomeres and cancer: a tale with many endings |
| Q29615353 | Telomeres and human disease: ageing, cancer and beyond |
| Q35131781 | Telomeres in cancer and aging: lessons from the mouse |
| Q34573210 | The Ku protein complex is involved in length regulation of Drosophila telomeres |
| Q39663183 | The NF90/NF45 complex participates in DNA break repair via nonhomologous end joining |
| Q52109680 | The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. |
| Q28115800 | The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cells |
| Q42086662 | The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1. |
| Q35980970 | The life and death of DNA-PK. |
| Q35136164 | The mammalian XRCC genes: their roles in DNA repair and genetic stability |
| Q37374755 | The mre11 complex and the response to dysfunctional telomeres |
| Q49906238 | The role of DNA-PK in aging and energy metabolism |
| Q35998861 | The telomerase cycle: normal and pathological aspects |
| Q33667323 | cDNA Expression Analysis of a Human Radiosensitive-Radioresistant Cell Line Model Identifies Telomere Function as a Hallmark of Radioresistance |
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