| Q35283684 | 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition |
| Q28116014 | A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed |
| Q34615449 | A quantitative assay for telomere protection in Saccharomyces cerevisiae |
| Q36283346 | ATM Inhibition Potentiates Death of Androgen Receptor-inactivated Prostate Cancer Cells with Telomere Dysfunction |
| Q33717036 | ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase |
| Q46164417 | Acquired genomic aberrations associated with methotrexate resistance vary with background genomic instability |
| Q35132550 | All things must end: telomere dynamics in yeast |
| Q33786814 | An alternate form of Ku80 is required for DNA end-binding activity in mammalian mitochondria |
| Q33900715 | An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres |
| Q39521368 | Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition |
| Q37033635 | Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability |
| Q35050968 | Assessment of telomere length and factors that contribute to its stability |
| Q34535672 | Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis |
| Q37508129 | Biological complexities in radiation carcinogenesis and cancer radiotherapy: impact of new biological paradigms |
| Q36671252 | Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells. |
| Q34416433 | Cellular senescence, cancer and aging: the telomere connection |
| Q35020477 | Centromere fission, not telomere erosion, triggers chromosomal instability in human carcinomas. |
| Q48139163 | Characterization of the telomere complex, TERF1 and TERF2 genes in muntjac species with fusion karyotypes |
| Q38552583 | Chromosomal Rearrangements in Cancer: Detection and potential causal mechanisms |
| Q37920517 | Chromosomal aberrations involving telomeres and interstitial telomeric sequences |
| Q34727255 | Chromosomal aberrations: formation, identification and distribution |
| Q34282271 | Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells |
| Q34152941 | Chromosome instability in human lung cancers: possible underlying mechanisms and potential consequences in the pathogenesis |
| Q42072170 | Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways |
| Q34086570 | Continuous hematopoietic cell lines as model systems for leukemia-lymphoma research |
| Q33549610 | DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA. |
| Q34775818 | DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. |
| Q34044618 | DNA damage to a single chromosome end delays anaphase onset |
| Q43109421 | DNA damage-induced phosphorylation of TRF2 is required for the fast pathway of DNA double-strand break repair. |
| Q34098695 | DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. |
| Q34405417 | DNA double strand break repair and chromosomal translocation: lessons from animal models |
| Q37112251 | DNA double-strand breaks: a potential causative factor for mammalian aging? |
| Q28509254 | DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 |
| Q36245188 | DNA repair and recombination functions in Arabidopsis telomere maintenance |
| Q46082292 | DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging. |
| Q53462272 | DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals. |
| Q34980859 | DNA-PKcs inhibition sensitizes cancer cells to carbon-ion irradiation via telomere capping disruption |
| Q33952920 | DNA-PKcs is critical for telomere capping |
| Q38976469 | DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres |
| Q28511262 | DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse |
| Q34474734 | DNA-dependent protein kinase catalytic subunit mediates T-cell loss in rheumatoid arthritis |
| Q92980463 | DNA-dependent protein kinase in telomere maintenance and protection |
| Q28266367 | DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase |
| Q39672684 | Defective Artemis causes mild telomere dysfunction |
| Q28513655 | Defective DNA repair and increased genomic instability in Artemis-deficient murine cells |
| Q35894811 | Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability |
| Q40666357 | Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. |
| Q24681223 | Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer |
| Q37510041 | Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair |
| Q73314798 | Differential DNA Binding of Ku Antigen Determines Its Involvement in DNA Replication |
| Q37695478 | Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism |
| Q39688137 | Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein |
| Q40352088 | Disruption of BRCA1 function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines |
| Q44105234 | Disruption of the Arabidopsis AtKu80 gene demonstrates an essential role for AtKu80 protein in efficient repair of DNA double-strand breaks in vivo |
| Q54692840 | Down-regulation of Ku 70 and Ku 80 mRNA expression in transitional cell carcinomas of the urinary bladder related to tumor progression. |
| Q36470593 | Dynamic regulation of single-stranded telomeres in Saccharomyces cerevisiae |
| Q33850943 | EBNA-LP associates with cellular proteins including DNA-PK and HA95. |
| Q39860143 | EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants |
| Q82430042 | Effect of Ku proteins on IRES-mediated translation |
| Q39677649 | Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells |
| Q48560666 | Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells |
| Q53388774 | Effects of p21 deletion in mouse models of premature aging. |
| Q36936810 | End joining at Caenorhabditis elegans telomeres |
| Q40161913 | Endonuclease-independent LINE-1 retrotransposition at mammalian telomeres |
| Q36226153 | Euchromatic and heterochromatic domains at Drosophila telomeres |
| Q40810954 | Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability |
| Q36247908 | Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer |
| Q36827578 | Frequent recombination in telomeric DNA may extend the proliferative life of telomerase-negative cells |
| Q34369713 | Functional interaction between DNA-PKcs and telomerase in telomere length maintenance |
| Q28139913 | Functional interaction between Ku and the werner syndrome protein in DNA end processing |
| Q46223955 | Functions of p53 suppress critical consequences of damage and repair in the initiation of cancer |
| Q28512255 | Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development |
| Q34391518 | Genomic instability and telomere fusion of canine osteosarcoma cells. |
| Q35611361 | Getting to the end: telomerase access in yeast and humans |
| Q39535234 | Homologous recombination is essential for RAD51 up-regulation in Saccharomyces cerevisiae following DNA crosslinking damage |
| Q28115815 | Human Ku70/80 associates physically with telomerase through interaction with hTERT |
| Q24562757 | Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint |
| Q24612772 | Human securin, hPTTG, is associated with Ku heterodimer, the regulatory subunit of the DNA-dependent protein kinase |
| Q46905568 | Identification and analysis of Ku70 and Ku80 homologs in the koji molds Aspergillus sojae and Aspergillus oryzae |
| Q35710278 | Identification of telomere dysfunction in Friedreich ataxia |
| Q36322778 | Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs |
| Q28505083 | Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions |
| Q24294826 | In vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complex |
| Q35632849 | Indecent exposure: when telomeres become uncapped |
| Q33220843 | Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells |
| Q37289254 | Inhibition of Snail1-DNA-PKcs protein-protein interface sensitizes cancer cells and inhibits tumor metastasis |
| Q37496089 | Insertion of telomeric repeats at intrachromosomal break sites during primate evolution |
| Q30453380 | Integrins regulate the apoptotic response to DNA damage through modulation of p53 |
| Q51091931 | Introduction to Telomeres and Telomerase. |
| Q35207184 | Ku acts in a unique way at the mammalian telomere to prevent end joining |
| Q24793684 | Ku and the Stability of the Genome |
| Q39864326 | Ku complex controls the replication time of DNA in telomere regions. |
| Q34470327 | Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis |
| Q24812323 | Ku protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cells |
| Q37012010 | Ku70 and non-homologous end joining protect testicular cells from DNA damage |
| Q24527652 | Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element |
| Q33894543 | Ku86 is essential in human somatic cells |
| Q34468156 | LINE-1 induces hTERT and ensures telomere maintenance in tumour cell lines. |
| Q39507697 | Lack of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) is accompanied by increased CK2α' levels |
| Q34276665 | Maintenance of double-stranded telomeric repeats as the critical determinant for cell viability in yeast cells lacking Ku. |
| Q24536297 | Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres |
| Q33757028 | Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhang |
| Q35569699 | Mammalian telomeres and telomerase: why they matter for cancer and aging |
| Q34535647 | Many ways to telomere dysfunction: in vivo studies using mouse models |
| Q34688443 | Mechanisms of chromosome-end protection |
| Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
| Q34348751 | Molecular analysis of telomere fusions in Arabidopsis: multiple pathways for chromosome end-joining |
| Q35003946 | Mouse models to study the role of telomeres in cancer, aging and DNA repair |
| Q35007775 | Murine Prkdc polymorphisms impact DNA-PKcs function |
| Q28504964 | Mus musculus and Mus spretus homologues of the human telomere-associated protein TIN2 |
| Q33840010 | Mutant huntingtin impairs Ku70-mediated DNA repair |
| Q39137894 | Mutations to Ku reveal differences in human somatic cell lines |
| Q24815695 | Non-homologous end joining, but not homologous recombination, enables survival for cells exposed to a histone deacetylase inhibitor |
| Q28260337 | Non-homologous end-joining, a sticky affair |
| Q36377992 | Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability |
| Q28354272 | Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe. |
| Q44388715 | Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response |
| Q41710554 | On the origin of Robertsonian fusions in nature: evidence of telomere shortening in wild house mice. |
| Q36454901 | PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis. |
| Q27309962 | PML is required for telomere stability in non-neoplastic human cells |
| Q33217702 | POT1 protects telomeres from a transient DNA damage response and determines how human chromosomes end |
| Q35033565 | Phosphoproteomic analysis of protein phosphorylation networks in Tetrahymena thermophila, a model single-celled organism. |
| Q47819568 | Plant telomere biology |
| Q40626771 | Protection of internal (TTAGGG)n repeats in Chinese hamster cells by telomeric protein TRF1. |
| Q29618391 | Protection of mammalian telomeres |
| Q30306228 | Protection of telomeres by the Ku protein in fission yeast |
| Q34095701 | Radiosensitive severe combined immunodeficiency disease |
| Q28214575 | Recombinational DNA repair and human disease |
| Q33559700 | Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction |
| Q34181022 | Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 |
| Q34361226 | Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs |
| Q40324038 | Repair of a minimal DNA double-strand break by NHEJ requires DNA-PKcs and is controlled by the ATM/ATR checkpoint |
| Q31816061 | Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex |
| Q24291434 | Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit |
| Q35169573 | Role of mammalian Rad54 in telomere length maintenance |
| Q39940494 | Role of the insulin-like growth factor I/insulin receptor substrate 1 axis in Rad51 trafficking and DNA repair by homologous recombination. |
| Q33719388 | SCID dogs: similar transplant potential but distinct intra-uterine growth defects and premature replicative senescence compared with SCID mice |
| Q24537136 | Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice |
| Q39647083 | Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK |
| Q39201974 | Structural and functional association of androgen receptor with telomeres in prostate cancer cells |
| Q35117867 | Structure-specific DNA-binding proteins as the foundation for three-dimensional chromatin organization |
| Q34478480 | Suppression of gross chromosomal rearrangements by yKu70-yKu80 heterodimer through DNA damage checkpoints |
| Q36772057 | TERRA, hnRNP A1, and DNA-PKcs Interactions at Human Telomeres |
| Q33878468 | TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends |
| Q35057049 | Take care of your chromosomes lest cancer take care of you. |
| Q35920252 | Targeted deletion reveals an essential function for the telomere length regulator Trf1. |
| Q48257265 | Telomerase dependence of telomere lengthening in Ku80 mutant Arabidopsis |
| Q61812921 | Telomere Biology and Human Phenotype |
| Q36103575 | Telomere biology: integrating chromosomal end protection with DNA damage response |
| Q36676871 | Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence |
| Q24336203 | Telomere dysfunction and cell survival: roles for distinct TIN2-containing complexes |
| Q78560248 | Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant |
| Q33937428 | Telomere dysfunction triggers developmentally regulated germ cell apoptosis. |
| Q30953207 | Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein |
| Q43460839 | Telomere length as a potential biomarker of coronary artery disease |
| Q34088540 | Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. |
| Q35132547 | Telomere length, telomere-binding proteins, and DNA damage signaling |
| Q24338140 | Telomere maintenance requires the RAD51D recombination/repair protein |
| Q35131785 | Telomere repeat binding factors: keeping the ends in check |
| Q34361251 | Telomere sister chromatid exchange and the process of aging |
| Q24304488 | Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases |
| Q35131777 | Telomere-driven genomic instability in cancer cells. |
| Q36309657 | Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis |
| Q37161449 | Telomeres do the (un)twist: helicase actions at chromosome termini |
| Q35131781 | Telomeres in cancer and aging: lessons from the mouse |
| Q34535605 | Telomeres, aging and cancer: in search of a happy ending |
| Q34595437 | Telomeres, chromosome instability and cancer |
| Q37384129 | Telomeres, histone code, and DNA damage response |
| Q38361193 | Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast |
| Q34183869 | Telomeric chromatin: replicating and wrapping up chromosome ends. |
| Q28081821 | The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis |
| Q34619414 | The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54 |
| Q40172226 | The Ku Heterodimer Performs Separable Activities at Double-Strand Breaks and Chromosome Termini |
| Q34573210 | The Ku protein complex is involved in length regulation of Drosophila telomeres |
| Q52109680 | The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice. |
| Q40647215 | The TP53 Dependence of Radiation-Induced Chromosome Instability in Human Lymphoblastoid Cells |
| Q33968202 | The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang. |
| Q24337452 | The human Rap1 protein complex and modulation of telomere length |
| Q42086662 | The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1. |
| Q34369810 | The impact energy metabolism and genome maintenance have on longevity and senescence: lessons from yeast to mammals |
| Q40494021 | The interaction of adenovirus E1A with the mammalian protein Ku70/XRCC6. |
| Q35132597 | The interplay between nonhomologous end-joining and cell cycle checkpoint factors in development, genomic stability, and tumorigenesis |
| Q35136164 | The mammalian XRCC genes: their roles in DNA repair and genetic stability |
| Q37374755 | The mre11 complex and the response to dysfunctional telomeres |
| Q24685574 | The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations |
| Q34417549 | The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity |
| Q49906238 | The role of DNA-PK in aging and energy metabolism |
| Q28296356 | The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control |
| Q35830410 | The role of the non-homologous end-joining pathway in lymphocyte development |
| Q35998861 | The telomerase cycle: normal and pathological aspects |
| Q37222775 | Tracking genomic instability within irradiated and bystander populations |
| Q54109933 | Tumor Cell-Accelerated Senescence Is Associated With DNA-PKcs Status and Telomere Dysfunction Induced by Radiation. |
| Q34245353 | Turning telomeres off and on. |
| Q33984271 | Tying up loose ends: nonhomologous end-joining in Saccharomyces cerevisiae |
| Q37130505 | Understanding and re-engineering nucleoprotein machines to cure human disease |
| Q35549049 | Which end: dissecting Ku's function at telomeres and double-strand breaks: Figure 1 |
| Q40458263 | Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. |
| Q33667323 | cDNA Expression Analysis of a Human Radiosensitive-Radioresistant Cell Line Model Identifies Telomere Function as a Hallmark of Radioresistance |