| scholarly article | Q13442814 |
| P356 | DOI | 10.1101/GAD.844000 |
| P8608 | Fatcat ID | release_tzatufel3va73fgn22y54oi42y |
| P932 | PMC publication ID | 317061 |
| P698 | PubMed publication ID | 11090128 |
| P5875 | ResearchGate publication ID | 277399662 |
| P2093 | author name string | S H Kim | |
| D Gilley | |||
| D J Chen | |||
| H L Hsu | |||
| T Kohwi-Shigematsu | |||
| B Allen | |||
| J Campisi | |||
| G C Li | |||
| M P Hande | |||
| S A Galande | |||
| P2860 | cites work | Elongated Telomeres inscidMice | Q61872134 |
| DNA end-joining: from yeast to man | Q63362924 | ||
| Characterization of the DNA-binding protein antigen Ku recognized by autoantibodies from patients with rheumatic disorders | Q68858908 | ||
| Telomeres--unsticky ends | Q77426228 | ||
| Mammalian telomeres end in a large duplex loop | Q22009893 | ||
| Ku is associated with the telomere in mammals | Q22010717 | ||
| TIN2, a new regulator of telomere length in human cells | Q22010863 | ||
| A mammalian factor that binds telomeric TTAGGG repeats in vitro | Q24293724 | ||
| Control of telomere length by the human telomeric protein TRF1 | Q24320111 | ||
| Extension of life-span by introduction of telomerase into normal human cells | Q24336088 | ||
| Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing | Q24533190 | ||
| Ku recruits the XRCC4-ligase IV complex to DNA ends | Q24554252 | ||
| Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination | Q28115740 | ||
| Interaction of Ku protein and DNA-dependent protein kinase catalytic subunit with nucleic acids | Q28608946 | ||
| The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae | Q29465403 | ||
| A critical role for telomeres in suppressing and facilitating carcinogenesis | Q33840458 | ||
| A sense of the end. | Q33927541 | ||
| Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance | Q34411525 | ||
| Molecular mechanisms of DNA double strand break repair | Q34484541 | ||
| Analysis of the mechanism of interaction of simian Ku protein with DNA | Q35788212 | ||
| DNA looping by Ku and the DNA-dependent protein kinase | Q36126604 | ||
| DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomes | Q36775252 | ||
| Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences | Q38322936 | ||
| Requirement for Ku80 in growth and immunoglobulin V(D)J recombination | Q38354221 | ||
| Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase | Q41035726 | ||
| Ku80 gene expression is Sp1-dependent and sensitive to CpG methylation within a novel cis element | Q41081073 | ||
| The telomere and telomerase: nucleic acid-protein complexes acting in a telomere homeostasis system. A review. | Q41703098 | ||
| The telomere and telomerase: how Do they interact? | Q46307416 | ||
| Biomolecular interaction analysis: affinity biosensor technologies for functional analysis of proteins. | Q47829922 | ||
| Two large subunits of the fission yeast RNA polymerase II provide platforms for the assembly of small subunits | Q47923564 | ||
| Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability | Q48564987 | ||
| P4510 | describes a project that uses | ImageQuant | Q112270642 |
| P433 | issue | 22 | |
| P304 | page(s) | 2807-2812 | |
| P577 | publication date | 2000-11-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Ku acts in a unique way at the mammalian telomere to prevent end joining | |
| P478 | volume | 14 |
| Q24305452 | A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends |
| Q28116014 | A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed |
| Q28213455 | A human interstitial telomere associates in vivo with specific TRF2 and TIN2 proteins |
| Q37350638 | A nonhomologous end-joining pathway is required for protein phosphatase 2A promotion of DNA double-strand break repair |
| Q51766693 | ATF7 mediates TNF-α-induced telomere shortening. |
| Q21145008 | Altered hematopoiesis in mice lacking DNA polymerase mu is due to inefficient double-strand break repair |
| Q34696128 | An analysis of CAF-1-interacting proteins reveals dynamic and direct interactions with the KU complex and 14-3-3 proteins. |
| Q33900715 | An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres |
| Q39746719 | Androgen receptor interacts with telomeric proteins in prostate cancer cells |
| Q35050968 | Assessment of telomere length and factors that contribute to its stability |
| Q34535672 | Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis |
| Q24678907 | Biochemical evidence for Ku-independent backup pathways of NHEJ |
| Q34416433 | Cellular senescence, cancer and aging: the telomere connection |
| Q34389487 | Characterization of the host factors required for hepadnavirus covalently closed circular (ccc) DNA formation |
| Q36662986 | Chromatin structure in telomere dynamics |
| Q28205315 | Chromosomal stability and the DNA double-stranded break connection |
| Q34282271 | Chromosome instability as a result of double-strand breaks near telomeres in mouse embryonic stem cells |
| Q33990112 | Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis. |
| Q33549610 | DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA. |
| Q34775818 | DNA amplification by breakage/fusion/bridge cycles initiated by spontaneous telomere loss in a human cancer cell line. |
| Q44196770 | DNA damage-induced inhibition of securin expression is mediated by p53. |
| Q34098695 | DNA damage-induced phosphorylation of the human telomere-associated protein TRF2. |
| Q37112251 | DNA double-strand breaks: a potential causative factor for mammalian aging? |
| Q28509254 | DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 |
| Q36245188 | DNA repair and recombination functions in Arabidopsis telomere maintenance |
| Q36865148 | DNA repair at telomeres: keeping the ends intact |
| Q33952920 | DNA-PKcs is critical for telomere capping |
| Q35638872 | DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication |
| Q38976469 | DNA-PKcs-interacting protein KIP binding to TRF2 is required for the maintenance of functional telomeres |
| Q28511262 | DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse |
| Q92980463 | DNA-dependent protein kinase in telomere maintenance and protection |
| Q28513655 | Defective DNA repair and increased genomic instability in Artemis-deficient murine cells |
| Q46070162 | Deleting Ku70 is milder than deleting Ku80 in p53-mutant mice and cells. |
| Q40666357 | Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. |
| Q24681223 | Deletion of Ku70, Ku80, or both causes early aging without substantially increased cancer |
| Q37510041 | Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair |
| Q39688137 | Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein |
| Q40503154 | Distinct profiles of critically short telomeres are a key determinant of different chromosome aberrations in immortalized human cells: whole-genome evidence from multiple cell lines. |
| Q54692840 | Down-regulation of Ku 70 and Ku 80 mRNA expression in transitional cell carcinomas of the urinary bladder related to tumor progression. |
| Q43234217 | Dysregulation of shelterin factors coupled with telomere shortening in Philadelphia chromosome negative myeloproliferative neoplasms |
| Q39860143 | EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants |
| Q52568689 | Enhanced gene targeting frequency in ku70 and ku80 disruption mutants of Aspergillus sojae and Aspergillus oryzae. |
| Q41867231 | Enhancement of extra chromosomal recombination in somatic cells by affecting the ratio of homologous recombination (HR) to non-homologous end joining (NHEJ). |
| Q36247908 | Fission yeast Rhp51 is required for the maintenance of telomere structure in the absence of the Ku heterodimer |
| Q37323568 | Function, replication and structure of the mammalian telomere |
| Q34369713 | Functional interaction between DNA-PKcs and telomerase in telomere length maintenance |
| Q36232699 | Functional interaction between poly(ADP-Ribose) polymerase 2 (PARP-2) and TRF2: PARP activity negatively regulates TRF2. |
| Q35853775 | Functional links between telomeres and proteins of the DNA-damage response |
| Q28131737 | Genome maintenance mechanisms for preventing cancer |
| Q35611361 | Getting to the end: telomerase access in yeast and humans |
| Q96022929 | H3K36 dimethylation by MMSET promotes classical non-homologous end-joining at unprotected telomeres |
| Q38300537 | Heat shock stimulation of a tilapia heat shock protein 70 promoter is mediated by a distal element |
| Q30959036 | How telomeres solve the end-protection problem |
| Q28115815 | Human Ku70/80 associates physically with telomerase through interaction with hTERT |
| Q24299861 | Human Ku70/80 interacts directly with hTR, the RNA component of human telomerase |
| Q28118848 | Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunction |
| Q24318525 | Human PinX1 mediates TRF1 accumulation in nucleolus and enhances TRF1 binding to telomeres |
| Q36451842 | Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere |
| Q46905568 | Identification and analysis of Ku70 and Ku80 homologs in the koji molds Aspergillus sojae and Aspergillus oryzae |
| Q36277224 | Identification of a gene involved in the synthesis of a dipeptidyl peptidase IV inhibitor in Aspergillus oryzae |
| Q35710278 | Identification of telomere dysfunction in Friedreich ataxia |
| Q36322778 | Impact of telomerase ablation on organismal viability, aging, and tumorigenesis in mice lacking the DNA repair proteins PARP-1, Ku86, or DNA-PKcs |
| Q44996406 | Importance of TRF1 for Functional Telomere Structure |
| Q39686949 | Increased telomere length and hypersensitivity to DNA damaging agents in an Arabidopsis KU70 mutant. |
| Q35632849 | Indecent exposure: when telomeres become uncapped |
| Q38363256 | Ku affects the ATM-dependent S phase checkpoint following ionizing radiation |
| Q24793684 | Ku and the Stability of the Genome |
| Q39864326 | Ku complex controls the replication time of DNA in telomere regions. |
| Q34470327 | Ku is required for telomeric C-rich strand maintenance but not for end-to-end chromosome fusions in Arabidopsis |
| Q33996667 | Ku must load directly onto the chromosome end in order to mediate its telomeric functions |
| Q56969633 | Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination |
| Q42647102 | Ku80 facilitates chromatin binding of the telomere binding protein, TRF2 |
| Q42127065 | Ku80-deleted cells are defective at base excision repair |
| Q24527652 | Ku86 autoantigen related protein-1 transcription initiates from a CpG island and is induced by p53 through a nearby p53 response element |
| Q33894543 | Ku86 is essential in human somatic cells |
| Q33906812 | Ku86 preserves chromatin integrity in cells adapted to high NaCl |
| Q92134232 | Loss of Ku's DNA end binding activity affects telomere length via destabilizing telomere-bound Est1 rather than altering TLC1 homeostasis |
| Q36245192 | Making the most of a little: dosage effects in eukaryotic telomere length maintenance |
| Q24536297 | Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres |
| Q35569699 | Mammalian telomeres and telomerase: why they matter for cancer and aging |
| Q34535647 | Many ways to telomere dysfunction: in vivo studies using mouse models |
| Q44200256 | Massive telomere loss is an early event of DNA damage-induced apoptosis |
| Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
| Q24599990 | Mouse embryonic stem cells, but not somatic cells, predominantly use homologous recombination to repair double-strand DNA breaks |
| Q35003946 | Mouse models to study the role of telomeres in cancer, aging and DNA repair |
| Q28504964 | Mus musculus and Mus spretus homologues of the human telomere-associated protein TIN2 |
| Q43852890 | Mutation in the glucose-6-phosphate dehydrogenase gene leads to inactivation of Ku DNA end binding during oxidative stress |
| Q39137894 | Mutations to Ku reveal differences in human somatic cell lines |
| Q36377992 | Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instability |
| Q44388715 | Novel localization of the DNA-PK complex in lipid rafts: a putative role in the signal transduction pathway of the ionizing radiation response |
| Q43239320 | OsKu70 is associated with developmental growth and genome stability in rice |
| Q42906128 | Ovate family protein 1 as a plant Ku70 interacting protein involving in DNA double-strand break repair |
| Q24619939 | Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system |
| Q40626771 | Protection of internal (TTAGGG)n repeats in Chinese hamster cells by telomeric protein TRF1. |
| Q29618391 | Protection of mammalian telomeres |
| Q33559700 | Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction |
| Q34181022 | Regulation of telomere length and suppression of genomic instability in human somatic cells by Ku86 |
| Q39578922 | Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection |
| Q33757674 | Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. |
| Q35125971 | Role of Telomeres and Telomerase in the Pathogenesis of Human Cancer |
| Q35169573 | Role of mammalian Rad54 in telomere length maintenance |
| Q24601577 | Shelterin complex and associated factors at human telomeres |
| Q24537136 | Shorter telomeres, accelerated ageing and increased lymphoma in DNA-PKcs-deficient mice |
| Q37971853 | Similarities and differences between "uncapped" telomeres and DNA double-strand breaks. |
| Q39647083 | Specific interaction of IP6 with human Ku70/80, the DNA-binding subunit of DNA-PK |
| Q39201974 | Structural and functional association of androgen receptor with telomeres in prostate cancer cells |
| Q34464911 | Survey of the year 2000 commercial optical biosensor literature |
| Q29615653 | Switching and signaling at the telomere |
| Q28116853 | TRF2 interaction with Ku heterotetramerization interface gives insight into c-NHEJ prevention at human telomeres |
| Q33878468 | TRF2/RAP1 and DNA-PK mediate a double protection against joining at telomeric ends |
| Q41342705 | Taking apart Rap1: an adaptor protein with telomeric and non-telomeric functions |
| Q35920252 | Targeted deletion reveals an essential function for the telomere length regulator Trf1. |
| Q35131774 | Telomerase and tumorigenesis |
| Q48257265 | Telomerase dependence of telomere lengthening in Ku80 mutant Arabidopsis |
| Q33855946 | Telomere Biology-Insights into an Intriguing Phenomenon. |
| Q34615813 | Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. |
| Q35882106 | Telomere biology in mammalian germ cells and during development |
| Q36103575 | Telomere biology: integrating chromosomal end protection with DNA damage response |
| Q40696254 | Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV |
| Q36884191 | Telomere dynamics: the means to an end. |
| Q30953207 | Telomere instability in a human tumor cell line expressing a dominant-negative WRN protein |
| Q34088540 | Telomere length deregulation and enhanced sensitivity to genotoxic stress in Arabidopsis mutants deficient in Ku70. |
| Q38038694 | Telomere length in reproduction |
| Q35193731 | Telomere maintenance and DNA replication: how closely are these two connected? |
| Q34743340 | Telomere maintenance as a target for anticancer drug discovery |
| Q24338140 | Telomere maintenance requires the RAD51D recombination/repair protein |
| Q35131785 | Telomere repeat binding factors: keeping the ends in check |
| Q35663645 | Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway |
| Q38152264 | Telomere-end processing: mechanisms and regulation |
| Q34768068 | Telomeres and aging |
| Q35131781 | Telomeres in cancer and aging: lessons from the mouse |
| Q34535605 | Telomeres, aging and cancer: in search of a happy ending |
| Q34595437 | Telomeres, chromosome instability and cancer |
| Q35851312 | Telomeres, telomerase, and apoptosis. |
| Q38361193 | Telomeric DNA ends are essential for the localization of Ku at telomeres in fission yeast |
| Q37419279 | Telomeric armor: the layers of end protection |
| Q34183869 | Telomeric chromatin: replicating and wrapping up chromosome ends. |
| Q40172226 | The Ku Heterodimer Performs Separable Activities at Double-Strand Breaks and Chromosome Termini |
| Q33968202 | The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang. |
| Q28744087 | The effect of DNA-dependent protein kinase on adeno-associated virus replication |
| Q42086662 | The human telomerase RNA component, hTR, activates the DNA-dependent protein kinase to phosphorylate heterogeneous nuclear ribonucleoprotein A1. |
| Q35136164 | The mammalian XRCC genes: their roles in DNA repair and genetic stability |
| Q36192029 | The mechanism of telomere protection: a comparison between Drosophila and humans. |
| Q35170919 | The role of DNA breaks in genomic instability and tumorigenesis |
| Q49906238 | The role of DNA-PK in aging and energy metabolism |
| Q28296356 | The role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint control |
| Q35730263 | The role of nonhomologous end-joining components in telomere metabolism in Kluyveromyces lactis |
| Q35998861 | The telomerase cycle: normal and pathological aspects |
| Q81024710 | The yeast VPS genes affect telomere length regulation |
| Q90744618 | Therapeutic Targets in Telomerase and Telomere Biology of Cancers |
| Q34655822 | Tiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology |
| Q34535610 | Transcriptional silencing at Saccharomyces telomeres: implications for other organisms |
| Q34245353 | Turning telomeres off and on. |
| Q40110935 | Uncoupling of telomere length and radiosensitivity in mouse lymphoma cell lines of similar genetic background |
| Q24634392 | Visualizing telomere dynamics in living mammalian cells using PNA probes |
| Q36859249 | WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand |
| Q40458263 | Widespread and nonrandom distribution of DNA palindromes in cancer cells provides a structural platform for subsequent gene amplification. |
| Q39212563 | p300-mediated acetylation of TRF2 is required for maintaining functional telomeres |
| Q40749074 | p53 binds telomeric single strand overhangs and t-loop junctions in vitro |
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