Telomere repeat binding factors: keeping the ends in check

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Telomere repeat binding factors: keeping the ends in check is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0304-3835(02)00706-1
P698PubMed publication ID12757977

P2093author name stringJan Karlseder
P2860cites workTankyrase, a poly(ADP-ribose) polymerase at human telomeresQ22008022
Mammalian telomeres end in a large duplex loopQ22009893
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatinQ34535628
Ku acts in a unique way at the mammalian telomere to prevent end joiningQ35207184
Normal telomere length and chromosomal end capping in poly(ADP-ribose) polymerase-deficient mice and primary cells despite increased chromosomal instabilityQ36377992
DNA double-strand break repair proteins are required to cap the ends of mammalian chromosomesQ36775252
Different telomere damage signaling pathways in human and mouse cellsQ39647901
Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoproteinQ40925366
Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G-rich single stranded DNA fragments.Q40926739
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stabilityQ48564987
Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.Q53406106
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome StabilityQ56508014
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient MiceQ56508064
Accelerated telomere shortening in ataxia telangiectasiaQ57017468
Extra-chromosomal telomeric DNA in cells from Atm-/- mice and patients with ataxia-telangiectasiaQ61872131
Elongated Telomeres inscidMiceQ61872134
Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblastsQ73311217
Ku binds telomeric DNA in vitroQ22010395
Ku is associated with the telomere in mammalsQ22010717
Nuclear structure in normal and Bloom syndrome cellsQ22253976
Identification of human Rap1: implications for telomere evolutionQ22254239
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeresQ22254585
Interaction of human Ku70 with TRF2Q24290239
TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpressionQ24291448
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitorQ24291889
Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2 at human telomeresQ24291989
A human telomeric proteinQ24304466
Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2Q24317670
Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeresQ24536297
The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and humanQ24546156
TRF2 Protects Human Telomeres from End-to-End FusionsQ28111898
Pot1, the putative telomere end-binding protein in fission yeast and humansQ28188476
Telomeric localization of TRF2, a novel human telobox proteinQ28314941
Strand-Specific Postreplicative Processing of Mammalian TelomeresQ28315729
Senescence Induced by Altered Telomere State, Not Telomere LossQ28315731
Telomere dysfunction and evolution of intestinal carcinoma in mice and humansQ28504673
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2Q28509254
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2Q28609749
Telomere shortening and tumor formation by mouse cells lacking telomerase RNAQ29615386
Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G-strand overhangQ33757028
Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.Q33757674
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouseQ33862948
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesisQ33862956
ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.Q33887607
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in miceQ33914498
The absence of the dna-dependent protein kinase catalytic subunit in mice results in anaphase bridges and in increased telomeric fusions with normal telomere length and G-strand overhang.Q33968202
T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhangQ34082359
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)189-197
P577publication date2003-05-01
P1433published inCancer LettersQ326372
P1476titleTelomere repeat binding factors: keeping the ends in check
P478volume194