| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2002PNAS...99.3597L |
| P356 | DOI | 10.1073/PNAS.062549199 |
| P932 | PMC publication ID | 122569 |
| P698 | PubMed publication ID | 11904422 |
| P5875 | ResearchGate publication ID | 11460461 |
| P50 | author | Mark D. Ungrin | Q50585449 |
| Murray O. Robinson | Q37380387 | ||
| P2093 | author name string | Lea Harrington | |
| Yie Liu | |||
| Hue Kha | |||
| P2860 | cites work | Tankyrase, a poly(ADP-ribose) polymerase at human telomeres | Q22008022 |
| Mammalian telomeres end in a large duplex loop | Q22009893 | ||
| A telomerase component is defective in the human disease dyskeratosis congenita | Q22010917 | ||
| Heterogeneity in telomere length of human chromosomes. | Q39426746 | ||
| The yeast telomere length counting machinery is sensitive to sequences at the telomere-nontelomere junction. | Q39444293 | ||
| Telomere length measurements using digital fluorescence microscopy | Q39512581 | ||
| The C terminus of the major yeast telomere binding protein Rap1p enhances telomere formation | Q39574489 | ||
| Impaired germinal center reaction in mice with short telomeres. | Q40387000 | ||
| Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase | Q40890122 | ||
| Rap1p and telomere length regulation in yeast. | Q41730851 | ||
| Progressive cis-inhibition of telomerase upon telomere elongation. | Q41855271 | ||
| Telomere dysfunction increases mutation rate and genomic instability | Q43709760 | ||
| Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae | Q46062549 | ||
| Severe growth defect in mouse cells lacking the telomerase RNA component | Q47991784 | ||
| Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry. | Q55067752 | ||
| The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability | Q56508014 | ||
| Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice | Q56508064 | ||
| Tankyrase promotes telomere elongation in human cells | Q56969704 | ||
| Presence of telomeric G-strand tails in the telomerase catalytic subunit TERT knockout mice | Q73231799 | ||
| The telomerase reverse transcriptase: components and regulation | Q22065785 | ||
| Control of telomere length by the human telomeric protein TRF1 | Q24320111 | ||
| Control of human telomere length by TRF1 and TRF2 | Q24554302 | ||
| Telomere shortening and apoptosis in telomerase-inhibited human tumor cells | Q24598974 | ||
| Specific Association of Human Telomerase Activity with Immortal Cells and Cancer | Q27860801 | ||
| Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. | Q27931258 | ||
| Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13 | Q27938764 | ||
| The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
| Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
| Telomerase catalytic subunit homologs from fission yeast and human | Q29615387 | ||
| Switching and signaling at the telomere | Q29615653 | ||
| TLC1: template RNA component of Saccharomyces cerevisiae telomerase | Q29618197 | ||
| Reverse transcriptase motifs in the catalytic subunit of telomerase | Q29618392 | ||
| The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse | Q29618622 | ||
| Essential role of mouse telomerase in highly proliferative organs | Q29620451 | ||
| Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activity | Q30471100 | ||
| Living with genome instability: plant responses to telomere dysfunction | Q33335422 | ||
| Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres. | Q33757674 | ||
| Telomere shortening in mTR-/- embryos is associated with failure to close the neural tube | Q33890481 | ||
| Disease states associated with telomerase deficiency appear earlier in mice with short telomeres | Q33890968 | ||
| Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA | Q33963894 | ||
| Haploinsufficiency of mTR results in defects in telomere elongation | Q34019216 | ||
| Positive and negative regulation of telomerase access to the telomere | Q34030866 | ||
| Telomeric chromatin: replicating and wrapping up chromosome ends. | Q34183869 | ||
| Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age. | Q34724924 | ||
| Identification of a nonprocessive telomerase activity from mouse cells | Q36110288 | ||
| Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice | Q36255827 | ||
| Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening | Q36449812 | ||
| A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation | Q36533927 | ||
| Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats | Q36657077 | ||
| Disruption of the telomerase catalytic subunit gene from Arabidopsis inactivates telomerase and leads to a slow loss of telomeric DNA | Q36774602 | ||
| Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells | Q38295184 | ||
| The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. | Q39120582 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | heterozygosity | Q124059385 |
| P304 | page(s) | 3597-3602 | |
| P577 | publication date | 2002-03-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert | |
| P478 | volume | 99 |
| Q26800129 | 5p deletions: Current knowledge and future directions |
| Q34154685 | A Cajal body-independent pathway for telomerase trafficking in mice |
| Q33375057 | A non-canonical function of zebrafish telomerase reverse transcriptase is required for developmental hematopoiesis |
| Q36786840 | A pathogenic dyskerin mutation impairs proliferation and activates a DNA damage response independent of telomere length in mice |
| Q36803215 | A translocation-defective telomerase with low levels of activity and processivity stabilizes short telomeres and confers immortalization |
| Q36916532 | ATM-like kinases and regulation of telomerase: lessons from yeast and mammals |
| Q33717036 | ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase |
| Q37122443 | Aging stem cells, latexin, and longevity |
| Q33900715 | An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres |
| Q38801561 | An intact putative mouse telomerase essential N-terminal domain is necessary for proper telomere maintenance |
| Q45953923 | Associations between cellular aging markers and metabolic syndrome: findings from the CARDIA study. |
| Q39831517 | Attenuated expression of SECIS binding protein 2 causes loss of telomeric reserve without affecting telomerase |
| Q35131769 | Biochemical aspects of telomerase function |
| Q35892080 | Concepts of human leukemic development. |
| Q24532112 | Deletion of the telomerase reverse transcriptase gene and haploinsufficiency of telomere maintenance in Cri du chat syndrome |
| Q38857763 | Depressive and anxiety disorders and short leukocyte telomere length: mediating effects of metabolic stress and lifestyle factors |
| Q95327407 | Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts |
| Q37646957 | Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice |
| Q35892131 | Does the reservoir for self-renewal stem from the ends? |
| Q33315749 | Dyskerin is a component of the Arabidopsis telomerase RNP required for telomere maintenance. |
| Q35841918 | Effects of Lifestyle Modification on Telomerase Gene Expression in Hypertensive Patients: A Pilot Trial of Stress Reduction and Health Education Programs in African Americans |
| Q36700876 | Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo |
| Q90238332 | Fluorescence spectroscopic detection and measurement of single telomere molecules |
| Q58862336 | From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond |
| Q37733930 | Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells |
| Q34019216 | Haploinsufficiency of mTR results in defects in telomere elongation |
| Q34713128 | Historical claims and current interpretations of replicative aging |
| Q37224778 | In situ visualization of telomere elongation patterns in human cells |
| Q34353587 | Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells |
| Q80349516 | Length regulation and dynamics of individual telomere tracts in wild-type Arabidopsis |
| Q36245192 | Making the most of a little: dosage effects in eukaryotic telomere length maintenance |
| Q35865757 | Molecular insights into the heterogeneity of telomere reprogramming in induced pluripotent stem cells. |
| Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
| Q28589866 | Murine Pif1 interacts with telomerase and is dispensable for telomere function in vivo |
| Q39906810 | No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells |
| Q41875894 | Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis |
| Q34483600 | PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres |
| Q35096706 | Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase |
| Q28593281 | Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit growth defects but have normal telomere length and capping |
| Q35920252 | Targeted deletion reveals an essential function for the telomere length regulator Trf1. |
| Q37750789 | Targeting telomerase in hematologic malignancy |
| Q37078833 | Telomerase and cancer therapeutics |
| Q37950142 | Telomerase regulation |
| Q37002134 | Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells |
| Q36495238 | Telomere length homeostasis |
| Q33933472 | Telomere length is inherited with resetting of the telomere set-point. |
| Q41918210 | Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts. |
| Q35959376 | Telomere shortening occurs early during breast tumorigenesis: a cause of chromosome destabilization underlying malignant transformation? |
| Q35193690 | The role of stem cells in aging |
| Q36070801 | Triallelic and epigenetic-like inheritance in human disorders of telomerase |
| Q33773225 | Two RNA subunits and POT1a are components of Arabidopsis telomerase |
| Q37246533 | Variable expression of Dkc1 mutations in mice |
| Q27642573 | YNMG tetraloop formation by a dyskeratosis congenita mutation in human telomerase RNA. |
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