scholarly article | Q13442814 |
P2093 | author name string | Lea A Harrington | |
Natalie Erdmann | |||
P2860 | cites work | A telomerase component is defective in the human disease dyskeratosis congenita | Q22010917 |
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) | Q24293520 | ||
Haploinsufficiency of telomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita | Q24536887 | ||
Human Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpoint | Q24562757 | ||
Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation | Q24563808 | ||
Mutations linked to dyskeratosis congenita cause changes in the structural equilibrium in telomerase RNA. | Q27640301 | ||
RPA-like proteins mediate yeast telomere function | Q27939798 | ||
Homologous recombination generates T-loop-sized deletions at human telomeres | Q28116970 | ||
DNA damage-induced activation of p53 by the checkpoint kinase Chk2 | Q28138195 | ||
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation | Q28145356 | ||
The RNA component of telomerase is mutated in autosomal dominant dyskeratosis congenita | Q28189076 | ||
Shelterin: the protein complex that shapes and safeguards human telomeres | Q28272546 | ||
Protein composition of catalytically active human telomerase from immortal cells | Q28295708 | ||
The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage | Q28586234 | ||
Conditional telomerase induction causes proliferation of hair follicle stem cells | Q28591715 | ||
Effects of telomerase and telomere length on epidermal stem cell behavior | Q28592564 | ||
DNA damage foci at dysfunctional telomeres | Q29614811 | ||
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA | Q29615386 | ||
A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
The Arabidopsis Pot1 and Pot2 proteins function in telomere length homeostasis and chromosome end protection | Q33221889 | ||
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle | Q33227804 | ||
Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protection | Q33255919 | ||
Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint | Q33266104 | ||
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance | Q33290676 | ||
Telomere length homeostasis | Q36495238 | ||
Telomere-related genome instability in cancer. | Q36547726 | ||
Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats | Q36657077 | ||
End Resection Initiates Genomic Instability in the Absence of Telomerase | Q37062471 | ||
Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice | Q37646957 | ||
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice. | Q38331074 | ||
The telomerase reverse transcriptase is limiting and necessary for telomerase function in vivo. | Q39120582 | ||
Different telomere damage signaling pathways in human and mouse cells | Q39647901 | ||
The nature of telomere fusion and a definition of the critical telomere length in human cells | Q40073766 | ||
Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells | Q40272786 | ||
Telomeres and senescence: the history, the experiment, the future | Q40863958 | ||
Telomerase subunit overexpression suppresses telomere-specific checkpoint activation in the yeast yku80 mutant | Q42724068 | ||
Telomere dysfunction increases mutation rate and genomic instability | Q43709760 | ||
Telomerase protects developing neurons against DNA damage-induced cell death | Q43806162 | ||
Ectopic expression of the catalytic subunit of telomerase protects against brain injury resulting from ischemia and NMDA-induced neurotoxicity. | Q44762653 | ||
Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae | Q46062549 | ||
Engineering the end: DNA processing at human telomeres | Q46443307 | ||
TERT promotes cellular and organismal survival independently of telomerase activity | Q46788573 | ||
A novel mechanism for telomere size control in Saccharomyces cerevisiae | Q47331172 | ||
The catalytic subunit of telomerase is expressed in developing brain neurons and serves a cell survival-promoting function. | Q52167636 | ||
Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA. | Q53851296 | ||
Telomere dysfunction and the initiation of genome instability. | Q55036686 | ||
Mutations of the human telomerase RNA gene (TERC) in aplastic anemia and myelodysplastic syndrome | Q73217622 | ||
Telomerase modulates expression of growth-controlling genes and enhances cell proliferation | Q73322990 | ||
Functional characterization of natural telomerase mutations found in patients with hematologic disorders | Q80312844 | ||
Mre 11 p nuclease activity is dispensable for telomeric rapid deletion | Q81912861 | ||
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. | Q33293671 | ||
The telomerase reverse transcriptase regulates chromatin state and DNA damage responses. | Q33852211 | ||
Haploinsufficiency of mTR results in defects in telomere elongation | Q34019216 | ||
Preferential maintenance of critically short telomeres in mammalian cells heterozygous for mTert. | Q34019245 | ||
Constitutive telomerase expression promotes mammary carcinomas in aging mice | Q34031827 | ||
The effect of TERC haploinsufficiency on the inheritance of telomere length | Q34144616 | ||
The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression | Q34166733 | ||
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism | Q34188701 | ||
Mutations in TERT, the gene for telomerase reverse transcriptase, in aplastic anemia | Q34409487 | ||
ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage | Q34453891 | ||
Very short telomeres in the peripheral blood of patients with X-linked and autosomal dyskeratosis congenita | Q34514264 | ||
New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin | Q34535628 | ||
Balancing instability: dual roles for telomerase and telomere dysfunction in tumorigenesis | Q34535672 | ||
Phosphorylation of H2AX at short telomeres in T cells and fibroblasts | Q34550319 | ||
Short telomeres, even in the presence of telomerase, limit tissue renewal capacity | Q34563497 | ||
Regulation of telomere elongation by the cyclin-dependent kinase CDK1. | Q34572159 | ||
Telomerase RNA levels limit the telomere length equilibrium | Q34578043 | ||
Differential suppression of DNA repair deficiencies of Yeast rad50, mre11 and xrs2 mutants by EXO1 and TLC1 (the RNA component of telomerase). | Q34614221 | ||
Short telomeres induce a DNA damage response in Saccharomyces cerevisiae | Q34813172 | ||
Telomerase: biochemical considerations for enzyme and substrate. | Q34989394 | ||
Mouse models for telomere and telomerase biology | Q35176465 | ||
Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion | Q35591723 | ||
Activation of the DNA damage response by telomere attrition: a passage to cellular senescence. | Q35700998 | ||
Those dam-aged telomeres! | Q35756005 | ||
Telomeres are double-strand DNA breaks hidden from DNA damage responses | Q35776499 | ||
Spreading of mammalian DNA-damage response factors studied by ChIP-chip at damaged telomeres | Q35837052 | ||
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita | Q35848013 | ||
Functional links between telomeres and proteins of the DNA-damage response | Q35853775 | ||
Human cell senescence as a DNA damage response. | Q35989854 | ||
Chromatin and the DNA damage response | Q36208346 | ||
Making the most of a little: dosage effects in eukaryotic telomere length maintenance | Q36245192 | ||
Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae | Q36392152 | ||
The maintenance and masking of chromosome termini | Q36471960 | ||
P433 | issue | 3 | |
P921 | main subject | DNA damage | Q5205747 |
P304 | page(s) | 347-353 | |
P577 | publication date | 2008-12-25 | |
P1433 | published in | DNA Repair | Q3894086 |
P1476 | title | No attenuation of the ATM-dependent DNA damage response in murine telomerase-deficient cells | |
P478 | volume | 8 |
Q35615304 | Accelerated hematopoietic stem cell aging in a mouse model of dyskeratosis congenita responds to antioxidant treatment |
Q33566461 | Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase |
Q39308305 | Long telomeres bypass the requirement for telomere maintenance in human tumorigenesis |
Q37833939 | Non-telomeric activities of telomerase. |
Q35096706 | Phenotypes in mTERT⁺/⁻ and mTERT⁻/⁻ mice are due to short telomeres, not telomere-independent functions of telomerase reverse transcriptase |
Q35597009 | Telomere shortening alters the kinetics of the DNA damage response after ionizing radiation in human cells |
Q36914679 | Telomeres, a busy platform for cell signaling. |
Q37846533 | Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins |
Q93086370 | Transient induction of telomerase expression mediates senescence and reduces tumorigenesis in primary fibroblasts |
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