Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

scientific article (publication date: September 2000)

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/79232
P3181OpenCitations bibliographic resource ID682902
P698PubMed publication ID10973255

P50authorKarl Lenhard RudolphQ21491023
P2093author name stringC Zhu
J Chaudhuri
K K Wong
R A DePinho
S Chang
S Ganesan
F W Alt
L Chin
S E Artandi
G J Gottlieb
S R Weiler
P2860cites workTelomere shortening and tumor formation by mouse cells lacking telomerase RNAQ29615386
Essential role of mouse telomerase in highly proliferative organsQ29620451
Sir-Ku-itous routes to make ends meetQ33684024
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesisQ33862956
Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patientQ33867168
Homology-directed repair is a major double-strand break repair pathway in mammalian cellsQ36065571
Chromosome healing in mouse embryonic stem cellsQ36381066
SYBR Green I staining of pulsed field agarose gels is a sensitive and inexpensive way of quantitating DNA double-strand breaks in mammalian cellsQ39720624
Telomeres and radiation-induced chromosome breakageQ41061466
Regulation and repair of double-strand DNA breaksQ41262073
Impairment of V(D)J recombination in double-strand break repair mutantsQ41560292
Acquisition of telomere repeat sequences by transfected DNA integrated at the site of a chromosome breakQ41576120
Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signalsQ45246384
Growth retardation and leaky SCID phenotype of Ku70-deficient mice.Q52191949
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient MiceQ56508064
Telomere capture stabilizes chromosome breakageQ58321639
p53 is linked directly to homologous recombination processes via RAD51/RecA protein interactionQ64386856
Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic miceQ73692219
A targeted DNA-PKcs-null mutation reveals DNA-PK-independent functions for KU in V(D)J recombinationQ77398644
DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytesQ22007974
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeastQ27936427
MEC1-dependent redistribution of the Sir3 silencing protein from telomeres to DNA double-strand breaksQ28137625
Genetic analysis of BRCA1 function in a defined tumor cell lineQ28142643
The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombinationQ28272412
A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesisQ28292871
Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IVQ28504490
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)85-8
P577publication date2000-09-01
P1433published inNature GeneticsQ976454
P1476titleTelomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation
P478volume26

Reverse relations

cites work (P2860)
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