scholarly article | Q13442814 |
P50 | author | Titia de Lange | Q2436934 |
P2093 | author name string | Bibo Li | |
P2860 | cites work | Tankyrase, a poly(ADP-ribose) polymerase at human telomeres | Q22008022 |
Mammalian telomeres end in a large duplex loop | Q22009893 | ||
TIN2, a new regulator of telomere length in human cells | Q22010863 | ||
Identification of human Rap1: implications for telomere evolution | Q22254239 | ||
Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres | Q22254585 | ||
TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression | Q24291448 | ||
The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor | Q24291889 | ||
Targeting assay to study the cis functions of human telomeric proteins: evidence for inhibition of telomerase by TRF1 and for activation of telomere degradation by TRF2 | Q24295044 | ||
POT1 as a terminal transducer of TRF1 telomere length control | Q24302841 | ||
A human telomeric protein | Q24304466 | ||
Control of telomere length by the human telomeric protein TRF1 | Q24320111 | ||
Control of human telomere length by TRF1 and TRF2 | Q24554302 | ||
NMR structure of the hRap1 Myb motif reveals a canonical three-helix bundle lacking the positive surface charge typical of Myb DNA-binding domains | Q27634722 | ||
The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA | Q27732682 | ||
A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae. | Q27932204 | ||
A protein-counting mechanism for telomere length regulation in yeast. | Q27932745 | ||
A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation | Q27937220 | ||
Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length | Q27938798 | ||
Senescence Induced by Altered Telomere State, Not Telomere Loss | Q28315731 | ||
Protection of mammalian telomeres | Q29618391 | ||
Regulation of telomere length and function by a Myb-domain protein in fission yeast | Q30470040 | ||
Intrachromatid excision of telomeric DNA as a mechanism for telomere size control in Saccharomyces cerevisiae | Q34012288 | ||
Structure and variability of human chromosome ends | Q34419028 | ||
Stringent sequence requirements for the formation of human telomeres | Q35751600 | ||
Telomere length regulation in mice is linked to a novel chromosome locus. | Q36209606 | ||
C-terminal truncation of RAP1 results in the deregulation of telomere size, stability, and function in Saccharomyces cerevisiae | Q36705317 | ||
Functional reintroduction of human telomeres into mammalian cells | Q37574052 | ||
Subsenescent telomere lengths in fibroblasts immortalized by limiting amounts of telomerase | Q40890122 | ||
Rap1p and telomere length regulation in yeast. | Q41730851 | ||
Progressive cis-inhibition of telomerase upon telomere elongation. | Q41855271 | ||
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats. | Q46017717 | ||
Runaway telomere elongation caused by telomerase RNA gene mutations | Q46144742 | ||
A novel mechanism for telomere size control in Saccharomyces cerevisiae | Q47331172 | ||
spRap1 and spRif1, recruited to telomeres by Taz1, are essential for telomere function in fission yeast | Q48336594 | ||
Telomere binding of the Rap1 protein is required for meiosis in fission yeast. | Q52544407 | ||
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability | Q56508014 | ||
Tankyrase promotes telomere elongation in human cells | Q56969704 | ||
RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability | Q68579298 | ||
P4510 | describes a project that uses | ImageQuant | Q112270642 |
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
heterogeneity | Q928498 | ||
TERF2 interacting protein | Q21136120 | ||
P304 | page(s) | 5060-8 | |
P577 | publication date | 2003-12-01 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | Rap1 affects the length and heterogeneity of human telomeres | |
P478 | volume | 14 |
Q24304485 | A dynamic molecular link between the telomere length regulator TRF1 and the chromosome end protector TRF2 |
Q39408275 | ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance. |
Q39825872 | Arginine methylation regulates telomere length and stability. |
Q40272786 | Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells |
Q35591723 | Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion |
Q39294995 | Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability |
Q33990112 | Crosstalk between telomere maintenance and radiation effects: A key player in the process of radiation-induced carcinogenesis. |
Q37058277 | DNA damage response at functional and dysfunctional telomeres |
Q42278533 | Decoding telomere protein Rap1: Its telomeric and nontelomeric functions and potential implications in diabetic cardiomyopathy |
Q37767830 | Defending the end zone: studying the players involved in protecting chromosome ends |
Q37646957 | Distinct dosage requirements for the maintenance of long and short telomeres in mTert heterozygous mice |
Q47222572 | Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis. |
Q37785995 | Dynamics of telomeric chromatin at the crossroads of aging and cancer |
Q64928360 | Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein. |
Q25257454 | Expression analysis of candidate breast tumour suppressor genes on chromosome 16q |
Q47947812 | Expression of Telomere Binding Proteins (RAP1 and POT1) in Renal Cell Carcinoma and Their Correlation with Clinicopathological Parameters |
Q37323568 | Function, replication and structure of the mammalian telomere |
Q35853775 | Functional links between telomeres and proteins of the DNA-damage response |
Q34952649 | Gene expression profiles associated with aging and mortality in humans |
Q33221984 | Genetic variation, nucleotide diversity, and linkage disequilibrium in seven telomere stability genes suggest that these genes may be under constraint |
Q36545398 | Heregulin, a new interactor of the telosome/shelterin complex in human telomeres. |
Q36545401 | Heregulin, a new regulator of telomere length in human cells |
Q40073650 | High Mobility Group A2 protects cancer cells against telomere dysfunction |
Q41952546 | Human RAP1 inhibits non-homologous end joining at telomeres |
Q36451842 | Human Rap1 interacts directly with telomeric DNA and regulates TRF2 localization at the telomere |
Q24676221 | Human Rif1 protein binds aberrant telomeres and aligns along anaphase midzone microtubules |
Q35676889 | Human Wrnip1 is localized in replication factories in a ubiquitin-binding zinc finger-dependent manner |
Q33851199 | Human telomeric proteins occupy selective interstitial sites |
Q36564417 | Hypothesis: Paralog Formation from Progenitor Proteins and Paralog Mutagenesis Spur the Rapid Evolution of Telomere Binding Proteins |
Q40171594 | Identification of candidate alternative lengthening of telomeres genes by methionine restriction and RNA interference. |
Q33866359 | Identification of differentially expressed genes in mouse hepatocarcinoma ascites cell line with low potential of lymphogenous metastasis |
Q34469940 | Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe |
Q28506435 | Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal |
Q36245192 | Making the most of a little: dosage effects in eukaryotic telomere length maintenance |
Q37425607 | Mammalian Rif1 contributes to replication stress survival and homology-directed repair |
Q57281887 | Mice lacking RAP1 show early onset and higher rates of DEN-induced hepatocellular carcinomas in female mice |
Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
Q24320254 | POT1 association with TRF2 regulates telomere length |
Q37353134 | Peripheral subnuclear positioning suppresses Tcrb recombination and segregates Tcrb alleles from RAG2. |
Q37619098 | Plasticity of telomere maintenance mechanisms in yeast |
Q33309165 | Pot1 and cell cycle progression cooperate in telomere length regulation |
Q45849924 | RAP1 protects from obesity through its extratelomeric role regulating gene expression |
Q27936253 | Rap1 prevents telomere fusions by nonhomologous end joining |
Q91972733 | Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy |
Q58796720 | STIM1 deficiency is linked to Alzheimer's disease and triggers cell death in SH-SY5Y cells by upregulation of L-type voltage-operated Ca entry |
Q37778877 | Structural identity of telomeric complexes |
Q27938428 | Subtelomeric proteins negatively regulate telomere elongation in budding yeast |
Q41882640 | TALEN gene knockouts reveal no requirement for the conserved human shelterin protein Rap1 in telomere protection and length regulation |
Q36670262 | TRF2-RAP1 is required to protect telomeres from engaging in homologous recombination-mediated deletions and fusions |
Q42957239 | Taz1, Rap1 and Rif1 act both interdependently and independently to maintain telomeres |
Q28075938 | Telomerase Regulation from Beginning to the End |
Q33756029 | Telomerase activation without shortening of telomeric 3'-overhang is a poor prognostic factor in human colorectal cancer |
Q36884191 | Telomere dynamics: the means to an end. |
Q36495238 | Telomere length homeostasis |
Q34410927 | Telomere length homeostasis requires that telomerase levels are limiting |
Q38174453 | Telomere length maintenance, shortening, and lengthening |
Q38032836 | Telomere lengthening and other functions of telomerase. |
Q37814480 | Telomere replication: poised but puzzling |
Q24812475 | Telomere structure and shortening in telomerase-deficient Trypanosoma brucei |
Q91846962 | Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis |
Q28587192 | Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression |
Q34310430 | Telomeres at a glance. |
Q37846533 | Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins |
Q24321534 | The Shwachman-Bodian-Diamond syndrome associated protein interacts with HsNip7 and its down-regulation affects gene expression at the transcriptional and translational levels |
Q24306780 | The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity |
Q24337452 | The human Rap1 protein complex and modulation of telomere length |
Q35998861 | The telomerase cycle: normal and pathological aspects |
Q37284026 | The telosome/shelterin complex and its functions |
Q89899802 | Trypanosoma brucei RAP1 Has Essential Functional Domains That Are Required for Different Protein Interactions |
Q33255919 | Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protection |
Q24307902 | XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening |
Q34420523 | Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status |
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