| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.1074968 |
| P698 | PubMed publication ID | 12169735 |
| P50 | author | Shu-Chun Teng | Q56862334 |
| P2093 | author name string | Virginia A Zakian | |
| Andrew K P Taggart | |||
| P433 | issue | 5583 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1023-1026 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Est1p as a cell cycle-regulated activator of telomere-bound telomerase | |
| P478 | volume | 297 |
| Q54478611 | "Poisoning" yeast telomeres distinguishes between redundant telomere capping pathways. |
| Q33718834 | 21st Century Genetics: Mass Spectrometry of Yeast Telomerase |
| Q42152601 | A balance between Tel1 and Rif2 activities regulates nucleolytic processing and elongation at telomeres |
| Q27933008 | A bulged stem tethers Est1p to telomerase RNA in budding yeast |
| Q38499861 | A date with telomerase: pick you up at S phase |
| Q36455420 | A flexible protein linker improves the function of epitope-tagged proteins in Saccharomyces cerevisiae |
| Q28116014 | A human homolog of yeast Est1 associates with telomerase and uncaps chromosome ends when overexpressed |
| Q41947741 | A new telomerase RNA element that is critical for telomere elongation |
| Q36898770 | A novel Tel1/ATM N-terminal motif, TAN, is essential for telomere length maintenance and a DNA damage response |
| Q35534966 | A second essential function of the Est1-binding arm of yeast telomerase RNA. |
| Q34231755 | A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle |
| Q36916532 | ATM-like kinases and regulation of telomerase: lessons from yeast and mammals |
| Q33228026 | Alterations of DNA and chromatin structures at telomeres and genetic instability in mouse cells defective in DNA polymerase alpha |
| Q40272786 | Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells |
| Q30312045 | Beginning to understand the end of the chromosome |
| Q35131769 | Biochemical aspects of telomerase function |
| Q36246606 | Biogenesis of telomerase ribonucleoproteins |
| Q36061897 | Budding yeast telomerase RNA transcription termination is dictated by the Nrd1/Nab3 non-coding RNA termination pathway. |
| Q38085607 | Cdc13 at a crossroads of telomerase action |
| Q98208982 | Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions |
| Q35810623 | Cdc13 telomere capping decreases Mec1 association but does not affect Tel1 association with DNA ends |
| Q37546015 | Cdk1 regulates the temporal recruitment of telomerase and Cdc13-Stn1-Ten1 complex for telomere replication |
| Q27934948 | Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. |
| Q29465400 | Cell cycle-dependent regulation of yeast telomerase by Ku. |
| Q36932943 | Cell cycle-dependent transcription factors control the expression of yeast telomerase RNA |
| Q24540240 | Cell cycle-regulated trafficking of human telomerase to telomeres |
| Q27930866 | Characterization of recombinant Saccharomyces cerevisiae telomerase core enzyme purified from yeast |
| Q37415045 | Chromosome end maintenance by telomerase |
| Q27934850 | Chromosome end protection plasticity revealed by Stn1p and Ten1p bypass of Cdc13p |
| Q35591723 | Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion |
| Q24647166 | Crystallization and preliminary X-ray analysis of the PIN domain of human EST1A |
| Q35615969 | DNA breaks are masked by multiple Rap1 binding in yeast: implications for telomere capping and telomerase regulation. |
| Q37058277 | DNA damage response at functional and dysfunctional telomeres |
| Q36865148 | DNA repair at telomeres: keeping the ends intact |
| Q27642532 | DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA |
| Q35656505 | DNA-end capping by the budding yeast transcription factor and subtelomeric binding protein Tbf1 |
| Q37021955 | Deletion of the major peroxiredoxin Tsa1 alters telomere length homeostasis |
| Q33408760 | Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres |
| Q33403245 | Distinct roles for yeast Stn1 in telomere capping and telomerase inhibition |
| Q92133842 | Eighteen 5,7-Dihalo-8-quinolinol and 2,2'-Bipyridine Co(II) Complexes as a New Class of Promising Anticancer Agents |
| Q41787808 | Est1 protects telomeres and inhibits subtelomeric y'-element recombination |
| Q35021955 | Ever shorter telomere 1 ( EST1 )-dependent reverse transcription by Candida telomerase in vitro : Evidence in support of an activating function |
| Q36154367 | Everything you ever wanted to know about Saccharomyces cerevisiae telomeres: beginning to end. |
| Q24606549 | Finding the end: recruitment of telomerase to telomeres |
| Q47319336 | Fission yeast Ccq1 is a modulator of telomerase activity. |
| Q43223959 | Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller. |
| Q37574098 | Fission yeast Dna2 is required for generation of the telomeric single-strand overhang |
| Q33281857 | Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere loss |
| Q37323568 | Function, replication and structure of the mammalian telomere |
| Q24619822 | Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance |
| Q24299999 | Functional conservation of the telomerase protein Est1p in humans |
| Q37733930 | Fundamental mechanisms of telomerase action in yeasts and mammals: understanding telomeres and telomerase in cancer cells |
| Q47948130 | Generation of Telomeric G Strand Overhangs Involves Both G and C Strand Cleavage |
| Q27940282 | Genetic analysis reveals essential and non-essential amino acids within the telomeric DNA-binding interface of Cdc13p |
| Q37421748 | Genetic dissection of the Kluyveromyces lactis telomere and evidence for telomere capping defects in TER1 mutants with long telomeres |
| Q39208015 | Genome-wide studies of telomere biology in budding yeast |
| Q35611361 | Getting to the end: telomerase access in yeast and humans |
| Q25257076 | High incidence of rapid telomere loss in telomerase-deficient Caenorhabditis elegans |
| Q41843323 | Highly transcribed RNA polymerase II genes are impediments to replication fork progression in Saccharomyces cerevisiae |
| Q24671304 | Histone deacetylase 8 safeguards the human ever-shorter telomeres 1B (hEST1B) protein from ubiquitin-mediated degradation |
| Q27932909 | Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation |
| Q40882874 | Holoenzyme proteins required for the physiological assembly and activity of telomerase |
| Q36948200 | How telomeres are replicated |
| Q36182484 | Human CST abundance determines recovery from diverse forms of DNA damage and replication stress |
| Q24650122 | Human Heterochromatin Protein 1 Isoforms HP1Hsα and HP1Hsβ Interfere with hTERT-Telomere Interactions and Correlate with Changes in Cell Growth and Response to Ionizing Radiation |
| Q24320113 | Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length |
| Q24303687 | Human POT1 facilitates telomere elongation by telomerase |
| Q24538105 | Human Pot1 (protection of telomeres) protein: cytolocalization, gene structure, and alternative splicing |
| Q37233984 | Human TEN1 maintains telomere integrity and functions in genome-wide replication restart |
| Q36149659 | Human cancer cells harbor T-stumps, a distinct class of extremely short telomeres |
| Q37810521 | Human telomerase activity regulation. |
| Q36383222 | Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase |
| Q43877520 | Identification of additional telomerase component of the yeast H. polymorpha is a step towards understanding the complex at the atomic level. |
| Q35893631 | Increased association of telomerase with short telomeres in yeast. |
| Q40437108 | Inhibitory effect of human telomerase antisense oligodeoxyribonucleotides on the growth of gastric cancer cell lines in variant tumor pathological subtype |
| Q33727774 | Insights into Cdc13 dependent telomere length regulation |
| Q37069656 | Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control |
| Q34609862 | Kinase-independent functions of TEL1 in telomere maintenance |
| Q80349516 | Length regulation and dynamics of individual telomere tracts in wild-type Arabidopsis |
| Q37092166 | Local chromatin structure at the ribosomal DNA causes replication fork pausing and genome instability in the absence of the S. cerevisiae DNA helicase Rrm3p |
| Q35667156 | Maintaining the end: roles of telomere proteins in end-protection, telomere replication and length regulation |
| Q36245192 | Making the most of a little: dosage effects in eukaryotic telomere length maintenance |
| Q37031809 | Modulation of telomere length dynamics by the subtelomeric region of tetrahymena telomeres |
| Q42213429 | Modulation of telomere terminal structure by telomerase components in Candida albicans |
| Q27930756 | Modulation of yeast telomerase activity by Cdc13 and Est1 in vitro |
| Q35920406 | Molecular characterization of the Schizosaccharomyces pombe nbs1+ gene involved in DNA repair and telomere maintenance |
| Q80855793 | Mre11 nuclease and C-terminal tail-mediated DDR functions are required for initiating yeast telomere healing |
| Q37072132 | Mutant telomeric repeats in yeast can disrupt the negative regulation of recombination-mediated telomere maintenance and create an alternative lengthening of telomeres-like phenotype |
| Q40207099 | Mutual dependence of Candida albicans Est1p and Est3p in telomerase assembly and activation |
| Q30310419 | N-terminal domain of yeast telomerase reverse transcriptase: recruitment of Est3p to the telomerase complex |
| Q34057250 | Normal telomere length maintenance in Saccharomyces cerevisiae requires nuclear import of the ever shorter telomeres 1 (Est1) protein via the importin alpha pathway |
| Q37084017 | Novel phosphorylation sites in the S. cerevisiae Cdc13 protein reveal new targets for telomere length regulation. |
| Q50061631 | Nuclear import of Cdc13 limits chromosomal capping |
| Q27934811 | Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA |
| Q35348694 | POT1a and components of CST engage telomerase and regulate its activity in Arabidopsis |
| Q27932588 | PP2A and Aurora differentially modify Cdc13 to promote telomerase release from telomeres at G2/M phase |
| Q36747492 | Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment |
| Q93083439 | Platinum(ii) complexes with rutaecarpine and tryptanthrin derivatives induce apoptosis by inhibiting telomerase activity and disrupting mitochondrial function |
| Q27938923 | Pol12, the B subunit of DNA polymerase alpha, functions in both telomere capping and length regulation |
| Q35676245 | Positive and negative regulation of Tetrahymena telomerase holoenzyme |
| Q37450636 | Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity |
| Q33649550 | Preserving Yeast Genetic Heritage through DNA Damage Checkpoint Regulation and Telomere Maintenance. |
| Q41792156 | Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiae |
| Q33789158 | Protection and replication of telomeres in fission yeast |
| Q33294968 | Protection of telomeres by a conserved Stn1-Ten1 complex |
| Q27930896 | Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length |
| Q27939516 | RPA facilitates telomerase activity at chromosome ends in budding and fission yeasts |
| Q27933681 | RPA regulates telomerase action by providing Est1p access to chromosome ends |
| Q27939798 | RPA-like proteins mediate yeast telomere function |
| Q38330395 | Rap1 binds single-stranded DNA at telomeric double- and single-stranded junctions and competes with Cdc13 protein. |
| Q27936253 | Rap1 prevents telomere fusions by nonhomologous end joining |
| Q34910981 | Rap1p telomere association is not required for mitotic stability of a C(3)TA(2) telomere in yeast |
| Q47587778 | Reciprocal association of the budding yeast ATM-related proteins Tel1 and Mec1 with telomeres in vivo |
| Q36483426 | Recombination-based telomere maintenance is dependent on Tel1-MRN and Rap1 and inhibited by telomerase, Taz1, and Ku in fission yeast |
| Q28472235 | Recruitment of Rad51 and Rad52 to short telomeres triggers a Mec1-mediated hypersensitivity to double-stranded DNA breaks in senescent budding yeast |
| Q34682248 | Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair |
| Q34271328 | Regulated assembly and disassembly of the yeast telomerase quaternary complex |
| Q26741230 | Regulating telomere length from the inside out: the replication fork model |
| Q28119138 | Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain |
| Q34572159 | Regulation of telomere elongation by the cyclin-dependent kinase CDK1. |
| Q27935645 | Regulation of telomere structure and functions by subunits of the INO80 chromatin remodeling complex |
| Q24603295 | Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1 |
| Q34130110 | Ribonucleoprotein multimers and their functions |
| Q36578934 | Roles of Pif1-like helicases in the maintenance of genomic stability. |
| Q35794091 | SUMOylation regulates telomere length homeostasis by targeting Cdc13. |
| Q25255779 | Saccharomyces cerevisiae Est3p dimerizes in vitro and dimerization contributes to efficient telomere replication in vivo |
| Q35674589 | Schizosaccharomyces pombe Ccq1 and TER1 bind the 14-3-3-like domain of Est1, which promotes and stabilizes telomerase-telomere association |
| Q33288733 | Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomerase |
| Q37176407 | Sequential loading of Saccharomyces cerevisiae Ku and Cdc13p to telomeres |
| Q28115535 | Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs |
| Q94483876 | Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP |
| Q97531475 | Structural insights into telomere protection and homeostasis regulation by yeast CST complex |
| Q28294594 | Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection |
| Q27678920 | Structure of the Human Telomeric Stn1-Ten1 Capping Complex |
| Q27936111 | Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replication |
| Q28241841 | Switching human telomerase on and off with hPOT1 protein in vitro |
| Q37425009 | TEN1 is essential for CDC13-mediated telomere capping |
| Q27931281 | TLC1 RNA nucleo-cytoplasmic trafficking links telomerase biogenesis to its recruitment to telomeres |
| Q33379093 | TOR regulates cell death induced by telomere dysfunction in budding yeast |
| Q38322972 | TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends |
| Q50476577 | Tandem affinity purification of AtTERT reveals putative interaction partners of plant telomerase in vivo. |
| Q27931882 | Tel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break. |
| Q35226701 | Telomerase activation after recruitment in fission yeast |
| Q46531438 | Telomerase and ATM/Tel1p protect telomeres from nonhomologous end joining |
| Q27934956 | Telomerase and Tel1p preferentially associate with short telomeres in S. cerevisiae. |
| Q38041010 | Telomerase caught in the act: united we stand, divided we fall |
| Q33373337 | Telomerase deficiency affects the formation of chromosomal translocations by homologous recombination in Saccharomyces cerevisiae |
| Q52551445 | Telomerase maintains telomere structure in normal human cells. |
| Q53476593 | Telomerase recruitment by the telomere end binding protein-beta facilitates G-quadruplex DNA unfolding in ciliates. |
| Q37950142 | Telomerase regulation |
| Q35651271 | Telomerase regulatory subunit Est3 in two Candida species physically interacts with the TEN domain of TERT and telomeric DNA. |
| Q36012625 | Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae |
| Q36854864 | Telomerase reverse transcriptase is required for the localization of telomerase RNA to cajal bodies and telomeres in human cancer cells |
| Q38966600 | Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions |
| Q41431137 | Telomerase-dependent generation of 70-nt-long telomeric single-stranded 3' overhangs in yeast. |
| Q34989394 | Telomerase: biochemical considerations for enzyme and substrate. |
| Q36495238 | Telomere length homeostasis |
| Q47699338 | Telomere length homeostasis is achieved via a switch between telomerase- extendible and -nonextendible states. |
| Q33754475 | Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei |
| Q37293044 | Telomere length regulation: coupling DNA end processing to feedback regulation of telomerase. |
| Q35193731 | Telomere maintenance and DNA replication: how closely are these two connected? |
| Q73216287 | Telomere maintenance in fission yeast requires an Est1 ortholog |
| Q36245204 | Telomere maintenance, function and evolution: the yeast paradigm. |
| Q35142887 | Telomere replication: an Est fest |
| Q38152264 | Telomere-end processing: mechanisms and regulation |
| Q33201004 | Telomeres and telomerase |
| Q34389435 | Telomeres and telomerase: their mechanisms of action and the effects of altering their functions |
| Q34194407 | Telomeres: structures in need of unwinding |
| Q27933555 | Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulation |
| Q37538214 | Tethering telomerase to telomeres increases genome instability and promotes chronological aging in yeast |
| Q37545165 | The 3' overhangs at Tetrahymena thermophila telomeres are packaged by four proteins, Pot1a, Tpt1, Pat1, and Pat2. |
| Q41997598 | The 5' arm of Kluyveromyces lactis telomerase RNA is critical for telomerase function |
| Q34616372 | The Est1 subunit of Saccharomyces cerevisiae telomerase makes multiple contributions to telomere length maintenance |
| Q37159901 | The Est3 protein associates with yeast telomerase through an OB-fold domain |
| Q30433767 | The Euplotes telomerase subunit p43 stimulates enzymatic activity and processivity in vitro |
| Q41792157 | The Hsp82 molecular chaperone promotes a switch between unextendable and extendable telomere states |
| Q39753325 | The Rad51 pathway of telomerase-independent maintenance of telomeres can amplify TG1-3 sequences in yku and cdc13 mutants of Saccharomyces cerevisiae. |
| Q27934054 | The S. cerevisiae Rrm3p DNA helicase moves with the replication fork and affects replication of all yeast chromosomes |
| Q28478064 | The Saccharomyces cerevisiae telomerase subunit Est3 binds telomeres in a cell cycle- and Est1-dependent manner and interacts directly with Est1 in vitro |
| Q28975759 | The TPR-containing domain within Est1 homologs exhibits species-specific roles in telomerase interaction and telomere length homeostasis |
| Q27933409 | The U3 small nucleolar ribonucleoprotein component Imp4p is a telomeric DNA-binding protein |
| Q34569656 | The amino terminus of the Saccharomyces cerevisiae DNA helicase Rrm3p modulates protein function altering replication and checkpoint activity |
| Q34042917 | The biogenesis and regulation of telomerase holoenzymes |
| Q37394791 | The conserved Est1 protein stimulates telomerase DNA extension activity |
| Q80027637 | The finger subdomain of yeast telomerase cooperates with Pif1p to limit telomere elongation |
| Q47338495 | The mechanisms of K. lactis Cdc13 in telomere DNA-binding and telomerase regulation |
| Q35137954 | The paradoxical relationship between NHEJ and telomeric fusion |
| Q35612954 | The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres. |
| Q27934097 | The role of Stn1p in Saccharomyces cerevisiae telomere capping can be separated from its interaction with Cdc13p |
| Q35998861 | The telomerase cycle: normal and pathological aspects |
| Q35179269 | The telomerase-recruitment domain of the telomere binding protein Cdc13 is regulated by Mec1p/Tel1p-dependent phosphorylation. |
| Q35651048 | The telomeric Cdc13 protein interacts directly with the telomerase subunit Est1 to bring it to telomeric DNA ends in vitro |
| Q34993950 | The tenacious recognition of yeast telomere sequence by Cdc13 is fully exerted by a single OB-fold domain |
| Q24791591 | The unusually large Plasmodium telomerase reverse-transcriptase localizes in a discrete compartment associated with the nucleolus |
| Q27930167 | The yeast Pif1p helicase removes telomerase from telomeric DNA. |
| Q37166062 | Toward accurate reconstruction of functional protein networks |
| Q34980899 | Tpz1 controls a telomerase-nonextendible telomeric state and coordinates switching to an extendible state via Ccq1. |
| Q33773225 | Two RNA subunits and POT1a are components of Arabidopsis telomerase |
| Q28473883 | Two pathways recruit telomerase to Saccharomyces cerevisiae telomeres |
| Q33785747 | Unwinding the functions of the Pif1 family helicases. |
| Q36498028 | Yeast Est2p affects telomere length by influencing association of Rap1p with telomeric chromatin |
| Q37175957 | Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination |
| Q30310619 | Yeast telomerase is specialized for C/A-rich RNA templates |
| Q27933320 | Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongation |
Search more.