Est1 protects telomeres and inhibits subtelomeric y'-element recombination

scientific article published on 10 January 2011

Est1 protects telomeres and inhibits subtelomeric y'-element recombination is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.00831-10
P932PMC publication ID3067898
P698PubMed publication ID21220516
P5875ResearchGate publication ID49742110

P2093author name stringXia-Jing Tong
Jin-Qiu Zhou
Ning-Ning Liu
Ming-Liang Zhang
Qian-Jin Li
Yi-Min Duan
P2860cites workA system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiaeQ27860636
Xrs2p regulates Mre11p translocation to the nucleus and plays a role in telomere elongation and meiotic recombinationQ27930233
Cdc13p: a single-strand telomeric DNA-binding protein with a dual role in yeast telomere maintenanceQ27930358
A mutant with a defect in telomere elongation leads to senescence in yeastQ27930429
The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 proteinQ27931011
Est1 has the properties of a single-stranded telomere end-binding proteinQ27931251
Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes.Q27931258
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome endsQ27932980
A bulged stem tethers Est1p to telomerase RNA in budding yeastQ27933008
Yeast telomerase subunit Est1p has guanine quadruplex-promoting activity that is required for telomere elongationQ27933320
EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiaeQ27933420
The Est3 protein is a subunit of yeast telomeraseQ27933462
Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiaeQ39449233
EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutantsQ39860143
Cdc13 both positively and negatively regulates telomere replicationQ40423693
Structure, function, and replication of Saccharomyces cerevisiae telomeresQ40955340
Proteasome-dependent degradation of Est1p regulates the cell cycle-restricted assembly of telomerase in Saccharomyces cerevisiaeQ41792156
Subtelomeric repeat amplification is associated with growth at elevated temperature in yku70 mutants of Saccharomyces cerevisiaeQ41871643
Limitations of silencing at native yeast telomeresQ42673247
Telomerase- and Rad52-independent immortalization of budding yeast by an inherited-long-telomere pathway of telomeric repeat amplification.Q43179667
Telomere maintenance is dependent on activities required for end repair of double-strand breaksQ47946099
Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activityQ56552038
Saccharomyces telomeres acquire single-strand TG1-3 tails late in S phaseQ70535280
Est1 and Cdc13 as comediators of telomerase accessQ73042124
Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational processQ73221736
Yeast Ku as a regulator of chromosomal DNA end structureQ74490854
Est1p as a cell cycle-regulated activator of telomere-bound telomeraseQ74593218
Telomerase, Ku, and telomeric silencing in Saccharomyces cerevisiaeQ77892451
Ten1p promotes the telomeric DNA-binding activity of Cdc13p: implication for its function in telomere length regulationQ27933555
Cdc13 delivers separate complexes to the telomere for end protection and replicationQ27933636
Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationQ27936111
Rap1 prevents telomere fusions by nonhomologous end joiningQ27936253
Stn1, a new Saccharomyces cerevisiae protein, is implicated in telomere size regulation in association with Cdc13.Q27937259
Ten1 functions in telomere end protection and length regulation in association with Stn1 and Cdc13Q27938764
Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpointQ27939822
Identification of a specific telomere terminal transferase activity in Tetrahymena extractsQ28306745
Two pathways recruit telomerase to Saccharomyces cerevisiae telomeresQ28473883
Regulation of telomerase by telomeric proteinsQ29616133
An alternative pathway for yeast telomere maintenance rescues est1- senescenceQ29616135
TLC1: template RNA component of Saccharomyces cerevisiae telomeraseQ29618197
Reverse transcriptase motifs in the catalytic subunit of telomeraseQ29618392
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activityQ30471100
Sensitivity of yeast strains with long G-tails to levels of telomere-bound telomeraseQ33288733
Telomere recombination accelerates cellular aging in Saccharomyces cerevisiaeQ33474860
An mre11 mutation that promotes telomere recombination and an efficient bypass of senescenceQ34007895
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiaeQ34035073
Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombinationQ34083558
Telomeres and their controlQ34090772
Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenanceQ34411525
RAD50 and RAD51 define two pathways that collaborate to maintain telomeres in the absence of telomeraseQ34606774
The Est1 subunit of Saccharomyces cerevisiae telomerase makes multiple contributions to telomere length maintenanceQ34616372
Telomerase: what are the Est proteins doing?Q35145812
Which end: dissecting Ku's function at telomeres and double-strand breaks: Figure 1Q35549049
Telomerase core components protect Candida telomeres from aberrant overhang accumulationQ35880346
Ku: a multifunctional protein involved in telomere maintenanceQ36175714
End Resection Initiates Genomic Instability in the Absence of TelomeraseQ37062471
A proposed OB-fold with a protein-interaction surface in Candida albicans telomerase protein Est3Q37131017
The Est3 protein associates with yeast telomerase through an OB-fold domainQ37159901
The yeast Pif1 helicase prevents genomic instability caused by G-quadruplex-forming CEB1 sequences in vivoQ37168915
Association of the Est1 protein with telomerase activity in yeastQ37677320
Quantitative amplification of single-stranded DNA (QAOS) demonstrates that cdc13-1 mutants generate ssDNA in a telomere to centromere directionQ38295081
A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiaeQ38318272
The yeast Ku heterodimer is essential for protection of the telomere against nucleolytic and recombinational activitiesQ38335557
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1263-1274
P577publication date2011-01-10
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleEst1 protects telomeres and inhibits subtelomeric y'-element recombination
P478volume31

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cites work (P2860)
Q54478611"Poisoning" yeast telomeres distinguishes between redundant telomere capping pathways.
Q98208982Cdc13 is predominant over Stn1 and Ten1 in preventing chromosome end fusions
Q27937911Characterization of the intramolecular G-quadruplex promoting activity of Est1.
Q27929502Inhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity
Q33557995Rad6-Bre1-mediated H2B ubiquitination regulates telomere replication by promoting telomere-end resection.
Q27930545Telomerase-null survivor screening identifies novel telomere recombination regulators.
Q26853108Telomeres-structure, function, and regulation
Q47425675The evolutionarily conserved factor Sus1/ENY2 plays a role in telomere length maintenance
Q47338495The mechanisms of K. lactis Cdc13 in telomere DNA-binding and telomerase regulation
Q34016553The principal role of Ku in telomere length maintenance is promotion of Est1 association with telomeres
Q47350265Using Separation-of-Function Mutagenesis To Define the Full Spectrum of Activities Performed by the Est1 Telomerase Subunit in Vivo

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