Telomerase enzyme activation and human cell immortalization

scientific article

Telomerase enzyme activation and human cell immortalization is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/S0378-4274(98)00278-1
P698PubMed publication ID10022230

P2093author name stringMeyerson M
P2860cites workA human telomeric proteinQ24304466
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalizationQ24310670
Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRTQ24313396
Control of telomere length by the human telomeric protein TRF1Q24320111
Extension of life-span by introduction of telomerase into normal human cellsQ24336088
Telomere elongation in immortal human cells without detectable telomerase activityQ24598626
Human telomerase contains evolutionarily conserved catalytic and structural subunitsQ24604009
Specific Association of Human Telomerase Activity with Immortal Cells and CancerQ27860801
A mutant with a defect in telomere elongation leads to senescence in yeastQ27930429
TRF2 Protects Human Telomeres from End-to-End FusionsQ28111898
Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomasQ28258624
The RNA component of human telomeraseQ28288330
Identification of a specific telomere terminal transferase activity in Tetrahymena extractsQ28306745
TLP1: a gene encoding a protein component of mammalian telomerase is a novel member of WD repeats familyQ28564535
A mammalian telomerase-associated proteinQ28595030
The serial cultivation of human diploid cell strainsQ29547356
Telomeres shorten during ageing of human fibroblastsQ29547357
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesisQ29614741
A survey of telomerase activity in human cancerQ29614858
Telomere shortening and tumor formation by mouse cells lacking telomerase RNAQ29615386
Telomerase catalytic subunit homologs from fission yeast and humanQ29615387
Structure and function of telomeresQ29615759
TLC1: template RNA component of Saccharomyces cerevisiae telomeraseQ29618197
Reverse transcriptase motifs in the catalytic subunit of telomeraseQ29618392
Essential role of mouse telomerase in highly proliferative organsQ29620451
Three Ever Shorter Telomere (EST) genes are dispensable for in vitro yeast telomerase activityQ30471100
Telomere reduction in human colorectal carcinoma and with ageingQ34037761
Developmental and tissue-specific regulation of mouse telomerase and telomere lengthQ34265760
The telomere terminal transferase of Tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificityQ34687302
Telomerase activity in human ovarian carcinomaQ35142569
The catalytic subunit of yeast telomeraseQ36558592
Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.Q36885740
Human cell transformation by simian virus 40—A reviewQ40124078
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomeraseQ41053498
Telomerase in yeastQ46265180
Addition of telomere-associated HeT DNA sequences "heals" broken chromosome ends in DrosophilaQ46354229
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAsQ46821624
Severe growth defect in mouse cells lacking the telomerase RNA componentQ47991784
Expression of TERT in early premalignant lesions and a subset of cells in normal tissuesQ47991825
Purification of Tetrahymena telomerase and cloning of genes encoding the two protein components of the enzymeQ48072977
Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life spanQ74311298
P304page(s)41-45
P577publication date1998-12-01
P1433published inToxicology LettersQ1796854
P1476titleTelomerase enzyme activation and human cell immortalization
P478volume102-103

Reverse relations

cites work (P2860)
Q37657533An immortalized steroidogenic goat granulosa cell line as a model system to study the effect of the endoplasmic reticulum (ER)-stress response on steroidogenesis.
Q63248527Brain organoids as a model system for human neurodevelopment and disease
Q36019105Chromosomal instability in oral cancer cells.
Q38828258Establishment and evaluation of a stable steroidogenic goat Leydig cell line
Q28749648Establishment, immortalisation and characterisation of pteropid bat cell lines
Q36764314FAK-Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique
Q33653268Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR.
Q41902780Molecular mechanisms of H. pylori associated gastric carcinogenesis
Q36209684Relationship between the expression of human telomerase reverse transcriptase gene and cell cycle regulators in gastric cancer and its significance
Q64446570Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform
Q43460839Telomere length as a potential biomarker of coronary artery disease

Search more.