scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1101201759 |
P356 | DOI | 10.1038/S41598-018-22217-9 |
P932 | PMC publication ID | 5832850 |
P698 | PubMed publication ID | 29497125 |
P50 | author | Pere Boadas-Vaello | Q39732553 |
Enrique Verdú | Q50531411 | ||
José Miguel Vela | Q56947146 | ||
P2093 | author name string | Georgia Gris | |
Sílvia Castany | |||
P2860 | cites work | Mechanisms of chronic central neuropathic pain after spinal cord injury | Q24655280 |
Inflammogenesis of Secondary Spinal Cord Injury | Q26752716 | ||
Generation and phenotypic analysis of sigma receptor type I (σ1) knockout mice | Q28184848 | ||
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival | Q28255981 | ||
Role of TNF-alpha during central sensitization in preclinical studies | Q28391879 | ||
Fyn kinase-mediated phosphorylation of NMDA receptor NR2B subunit at Tyr1472 is essential for maintenance of neuropathic pain | Q28505978 | ||
Quantitative assessment of tactile allodynia in the rat paw | Q29617366 | ||
Ethical guidelines for investigations of experimental pain in conscious animals | Q29617510 | ||
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia | Q29620385 | ||
MAP kinase and pain | Q30482277 | ||
Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system | Q30859681 | ||
Gait analysis in normal and spinal contused mice using the TreadScan system | Q33618985 | ||
Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization | Q34260033 | ||
Global prevalence and incidence of traumatic spinal cord injury | Q34265912 | ||
Role of sigma-1 receptors in paclitaxel-induced neuropathic pain in mice | Q34305923 | ||
TNF-α contributes to spinal cord synaptic plasticity and inflammatory pain: distinct role of TNF receptor subtypes 1 and 2. | Q34496543 | ||
Sigma-1 receptor and inflammatory pain. | Q34669463 | ||
The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems. | Q34675713 | ||
Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival | Q35034908 | ||
Intracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root | Q35069330 | ||
Novel Therapeutic Targets in Neuroinflammation and Neuropathic Pain | Q35688300 | ||
MAPK activation in nociceptive neurons and pain hypersensitivity | Q35711680 | ||
Regulation of NMDA receptors by phosphorylation | Q36026713 | ||
Neuropathic pain prevalence following spinal cord injury: A systematic review and meta-analysis. | Q36061109 | ||
The ERK/MAPK pathway, as a target for the treatment of neuropathic pain | Q36219694 | ||
p38 MAPK, microglial signaling, and neuropathic pain | Q36345136 | ||
Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice | Q36768687 | ||
Long-term actions of interleukin-1beta on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization | Q37059278 | ||
Spinal cord mechanisms of pain | Q37140262 | ||
Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury | Q37357665 | ||
Central sensitization: a generator of pain hypersensitivity by central neural plasticity | Q37361185 | ||
Targeting the NMDA receptor subunit NR2B for the treatment of neuropathic pain | Q37374352 | ||
Recent advances in understanding neuropathic pain: glia, sex differences, and epigenetics | Q37577709 | ||
Sigma 1 receptor: a new therapeutic target for pain. | Q38090302 | ||
Burden of spinal cord injury-related neuropathic pain in the United States: retrospective chart review and cross-sectional survey | Q38099217 | ||
Neuropathic pain and cytokines: current perspectives | Q38167771 | ||
Spinal cord injury models: a review. | Q38218856 | ||
An increase in spinal dehydroepiandrosterone sulfate (DHEAS) enhances NMDA-induced pain via phosphorylation of the NR1 subunit in mice: involvement of the sigma-1 receptor | Q38483796 | ||
Investigational sigma-1 receptor antagonists for the treatment of pain. | Q38513640 | ||
Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment | Q38591395 | ||
Spinal cord injury-induced pain: mechanisms and treatments | Q38592156 | ||
Antinociception by Sigma-1 Receptor Antagonists: Central and Peripheral Effects. | Q38751845 | ||
P2 receptors, microglial cytokines and chemokines, and neuropathic pain | Q38885571 | ||
Neuropathic pain following traumatic spinal cord injury: Models, measurement, and mechanisms | Q38951838 | ||
The σ-1 receptor interacts directly with GluN1 but not GluN2A in the GluN1/GluN2A NMDA receptor | Q39063368 | ||
Neuronal and microglial mechanisms for neuropathic pain in the spinal dorsal horn and anterior cingulate cortex. | Q39157732 | ||
Neuropathic Pain: Central vs. Peripheral Mechanisms | Q39255819 | ||
The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats | Q40273622 | ||
Extracellular signal-regulated protein kinase activation in spinal cord contributes to pain hypersensitivity in a mouse model of type 2 diabetes | Q41457878 | ||
Identification of MEK1 as a novel target for the treatment of neuropathic pain | Q42267806 | ||
Endoplasmic Reticulum Stress and Disrupted Neurogenesis in the Brain Are Associated with Cognitive Impairment and Depressive-Like Behavior after Spinal Cord Injury. | Q42740692 | ||
The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control | Q43195386 | ||
EphrinB2 induces tyrosine phosphorylation of NR2B via Src-family kinases during inflammatory hyperalgesia. | Q43233609 | ||
Role of the spinal cord NR2B-containing NMDA receptors in the development of neuropathic pain | Q45815924 | ||
Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice. | Q46046241 | ||
Activation of the ERK1/2 signaling cascade by excitotoxic spinal cord injury | Q46515705 | ||
Expression of the purported sigma(1) (sigma(1)) receptor in the mammalian brain and its possible relevance in deficits induced by antagonism of the NMDA receptor complex as revealed using an antisense strategy | Q46613593 | ||
Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. | Q47860279 | ||
Tumor necrosis factor-mediated downregulation of spinal astrocytic connexin43 leads to increased glutamatergic neurotransmission and neuropathic pain in mice | Q48106677 | ||
Spinal cord injury induces a long-lasting upregulation of interleukin-1β in astrocytes around the central canal. | Q48432720 | ||
Dehydroepiandrosterone sulfate prevents ischemia-induced impairment of long-term potentiation in rat hippocampal CA1 by up-regulating tyrosine phosphorylation of NMDA receptor | Q48452254 | ||
Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus | Q48485015 | ||
Effect of NMDA NR2B antagonist on neuropathic pain in two spinal cord injury models | Q48712867 | ||
Epigallocatechin-3-gallate treatment reduces thermal hyperalgesia after spinal cord injury by down-regulating RhoA expression in mice | Q50279096 | ||
Sigma-1 receptor knockout impairs neurogenesis in dentate gyrus of adult hippocampus via down-regulation of NMDA receptors. | Q50928213 | ||
Basso Mouse Scale for locomotion detects differences in recovery after spinal cord injury in five common mouse strains. | Q51204340 | ||
The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. | Q51750311 | ||
Increases in the activated forms of ERK 1/2, p38 MAPK, and CREB are correlated with the expression of at-level mechanical allodynia following spinal cord injury. | Q51950848 | ||
The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states | Q52237708 | ||
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn. | Q52535137 | ||
Effects of centrally acting analgesics on spinal segmental reflexes and wind-up. | Q52996667 | ||
Sigma-1 Receptor and Pain. | Q53647635 | ||
A new definition of neuropathic pain | Q57987223 | ||
ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model | Q57990428 | ||
Spinal ERK activation contributes to the regulation of bladder function in spinal cord injured rats | Q59282681 | ||
Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury | Q60713091 | ||
Involvement of spinal phosphorylation cascade of Tyr1472-NR2B, Thr286-CaMKII, and Ser831-GluR1 in neuropathic pain | Q60735118 | ||
Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation | Q69808015 | ||
A mouse model of graded contusive spinal cord injury | Q74343653 | ||
Formalin-induced pain is reduced in sigma(1) receptor knockout mice | Q81545494 | ||
Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats | Q83371437 | ||
Central sensitization needs sigma receptors | Q84170778 | ||
Effects of the selective sigma-1 receptor antagonist S1RA on formalin-induced pain behavior and neurotransmitter release in the spinal cord in rats | Q87023943 | ||
Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors | Q87462009 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | neuropathic pain | Q2798704 |
P304 | page(s) | 3873 | |
P577 | publication date | 2018-03-01 | |
P1433 | published in | Scientific Reports | Q2261792 |
P1476 | title | Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice. | |
P478 | volume | 8 |
Q58801968 | A pilot study of neuromuscular electrical stimulation for neuropathic pain caused by spinal cord injury |
Q60731228 | Allopregnanolone and Progesterone in Experimental Neuropathic Pain: Former and New Insights with a Translational Perspective |
Q64068169 | Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain |
Q92562255 | Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids |
Q64101832 | Neuroleptanalgesia for acute abdominal pain: a systematic review |
Q64061491 | Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice |
Q95327470 | Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain |
Q57051003 | Structural basis for σ receptor ligand recognition |
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