| scholarly article | Q13442814 |
| P2093 | author name string | X Codony | |
| M Merlos | |||
| E Hernández | |||
| L Romero | |||
| J Burgueño | |||
| A Bura | |||
| A Dordal | |||
| A Montero | |||
| A Muro | |||
| C R Plata-Salamán | |||
| C Segalés | |||
| D Zamanillo | |||
| E Portillo-Salido | |||
| G Encina | |||
| I Rivera-Arconada | |||
| J A López-García | |||
| J Giraldo | |||
| J M Baeyens | |||
| J M Vela | |||
| M Escriche | |||
| M Laloya | |||
| R Maldonado | |||
| R Sánchez-Arroyos | |||
| X Nadal | |||
| P2860 | cites work | Central sensitization needs sigma receptors | Q84170778 |
| Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction | Q28188127 | ||
| Immunocytochemical localization of the sigma(1) receptor in the adult rat central nervous system | Q30859681 | ||
| Sigma 1 receptor modulation of G-protein-coupled receptor signaling: potentiation of opioid transduction independent from receptor binding | Q33754837 | ||
| Wind-up of spinal cord neurones and pain sensation: much ado about something? | Q33855413 | ||
| The sigma-1 receptor chaperone as an inter-organelle signaling modulator | Q34356970 | ||
| Sigma-1 Receptor Antagonist BD1047 Reduces Allodynia and Spinal ERK Phosphorylation Following Chronic Compression of Dorsal Root Ganglion in Rats | Q34554003 | ||
| Irreversible blockade of sigma-1 receptors by haloperidol and its metabolites in guinea pig brain and SH-SY5Y human neuroblastoma cells | Q34617396 | ||
| Intrathecal injection of the sigma(1) receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain | Q34863848 | ||
| Sigma-1 receptor chaperones and diseases | Q35149248 | ||
| Intrathecal treatment with sigma1 receptor antagonists reduces formalin-induced phosphorylation of NMDA receptor subunit 1 and the second phase of formalin test in mice | Q35546029 | ||
| Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice | Q36768687 | ||
| Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. | Q37225259 | ||
| Central sensitization: a generator of pain hypersensitivity by central neural plasticity | Q37361185 | ||
| The pharmacology of sigma-1 receptors | Q37445561 | ||
| Pharmacology and therapeutic potential of sigma(1) receptor ligands | Q37545379 | ||
| Sigma-1 receptor-induced increase in murine spinal NR1 phosphorylation is mediated by the PKCalpha and epsilon, but not the PKCzeta, isoforms. | Q38486214 | ||
| Guidelines for reporting experiments involving animals: the ARRIVE guidelines | Q39512979 | ||
| The sigma-1 receptor modulates NMDA receptor synaptic transmission and plasticity via SK channels in rat hippocampus. | Q42601878 | ||
| Sigma1 receptor modulation of opioid analgesia in the mouse | Q43893570 | ||
| Sigma receptors inhibit high-voltage-activated calcium channels in rat sympathetic and parasympathetic neurons | Q44010643 | ||
| Selective antagonism of opioid analgesia by a sigma system | Q44337301 | ||
| N-methyl-D-aspartate-induced neuronal activation is selectively modulated by sigma receptors | Q44728971 | ||
| Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. | Q45072859 | ||
| Characterization of the binding of [3H](+)-pentazocine to sigma recognition sites in guinea pig brain | Q45096400 | ||
| Phenytoin differentially modulates the affinity of agonist and antagonist ligands for sigma 1 receptors of guinea pig brain | Q45213886 | ||
| Sigma-1 receptors are essential for capsaicin-induced mechanical hypersensitivity: studies with selective sigma-1 ligands and sigma-1 knockout mice. | Q46046241 | ||
| sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons | Q46413616 | ||
| Antinociceptive effects of haloperidol and its metabolites in the formalin test in mice | Q46630813 | ||
| Neurosteroid dehydroepiandrosterone sulphate inhibits persistent sodium currents in rat medial prefrontal cortex via activation of sigma-1 receptors | Q46884723 | ||
| Spinal NMDA receptor phosphorylation correlates with the presence of neuropathic signs following peripheral nerve injury in the rat. | Q46937094 | ||
| Potentiation of neuronal NMDA response induced by dehydroepiandrosterone and its suppression by progesterone: effects mediated via sigma receptors. | Q49158867 | ||
| The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity states | Q52237708 | ||
| Operational models of pharmacological agonism. | Q52699226 | ||
| Modulation by sigma ligands of intracellular free Ca++ mobilization by N-methyl-D-aspartate in primary culture of rat frontal cortical neurons | Q57222038 | ||
| Sigma-1 receptors regulate activity-induced spinal sensitization and neuropathic pain after peripheral nerve injury | Q60713091 | ||
| Evidence for a role of the NMDA receptor in the frequency dependent potentiation of deep rat dorsal horn nociceptive neurones following C fibre stimulation | Q69808015 | ||
| Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration | Q73929999 | ||
| Formalin-induced pain is reduced in sigma(1) receptor knockout mice | Q81545494 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | pharmacology | Q128406 |
| neuropathic pain | Q2798704 | ||
| P304 | page(s) | 2289-2306 | |
| P577 | publication date | 2012-08-01 | |
| P1433 | published in | British Journal of Pharmacology | Q919631 |
| P1476 | title | Pharmacological properties of S1RA, a new sigma-1 receptor antagonist that inhibits neuropathic pain and activity-induced spinal sensitization | |
| P478 | volume | 166 |
| Q60933437 | An integrated review on new targets in the treatment of neuropathic pain |
| Q37464562 | Antinociceptive Profile of Levo-tetrahydropalmatine in Acute and Chronic Pain Mice Models: Role of spinal sigma-1 receptor. |
| Q51008974 | Assessment of the sigma-1 receptor antagonist (SR1A): a model approach for preclinical analgesic drug discovery. |
| Q39657197 | Blockade of sigma 1 receptors alleviates sensory signs of diabetic neuropathy in rats |
| Q64068169 | Blockade of the Sigma-1 Receptor Relieves Cognitive and Emotional Impairments Associated to Chronic Osteoarthritis Pain |
| Q58732614 | Cannabidiol enhances morphine antinociception, diminishes NMDA-mediated seizures and reduces stroke damage via the sigma 1 receptor |
| Q39167151 | Chaperone Proteins in the Central Nervous System and Peripheral Nervous System after Nerve Injury |
| Q64998248 | Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain. |
| Q53443172 | Critical role of sigma-1 receptors in central neuropathic pain-related behaviours after mild spinal cord injury in mice. |
| Q85949364 | Effects of a selective sigma 1 antagonist compound on inflammatory pain |
| Q52996667 | Effects of centrally acting analgesics on spinal segmental reflexes and wind-up. |
| Q47266458 | Efficacy of a Novel Sigma-1 Receptor Antagonist for Oxaliplatin-Induced Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase IIa Clinical Trial. |
| Q42317501 | Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction |
| Q42038627 | Evaluation of σ-1 receptor radioligand 18F-FTC-146 in rats and squirrel monkeys using PET. |
| Q42330172 | Exploring Drug-Receptor Interaction Kinetics: Lessons from a Sigma-1 Receptor Transmembrane Biosensor |
| Q55340475 | Fenfluramine diminishes NMDA receptor-mediated seizures via its mixed activity at serotonin 5HT2A and type 1 sigma receptors. |
| Q38513640 | Investigational sigma-1 receptor antagonists for the treatment of pain. |
| Q64889678 | Ligands Exert Biased Activity to Regulate Sigma 1 Receptor Interactions With Cationic TRPA1, TRPV1, and TRPM8 Channels. |
| Q58094972 | May a sigma-1 antagonist improve neuropathic signs induced by cisplatin and vincristine in rats? |
| Q64110973 | Modulation by Sigma-1 Receptor of Morphine Analgesia and Tolerance: Nociceptive Pain, Tactile Allodynia and Grip Strength Deficits During Joint Inflammation |
| Q64093876 | Molecular Interplay Between the Sigma-1 Receptor, Steroids, and Ion Channels |
| Q52478636 | New consensus multivariate models based on PLS and ANN studies of sigma-1 receptor antagonists. |
| Q42743497 | New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects |
| Q34313161 | Operant self-administration of a sigma ligand improves nociceptive and emotional manifestations of neuropathic pain. |
| Q38896666 | Pharmacological Modulation of the Sigma 1 Receptor and the Treatment of Pain |
| Q51741747 | Possible involvement of the Sigma-1 receptor chaperone in chemotherapeutic-induced neuropathic pain. |
| Q64061491 | Repeated Sigma-1 Receptor Antagonist MR309 Administration Modulates Central Neuropathic Pain Development After Spinal Cord Injury in Mice |
| Q38422557 | Role of peripheral sigma-1 receptors in ischaemic pain: Potential interactions with ASIC and P2X receptors. |
| Q41714466 | Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases |
| Q34275887 | Safety, tolerability and pharmacokinetics of single and multiple doses of a novel sigma-1 receptor antagonist in three randomized phase I studies |
| Q38235503 | Selective sigma-1 receptor antagonists for the treatment of pain. |
| Q39153819 | Sigma 2 Receptor/Tmem97 Agonists Produce Long Lasting Antineuropathic Pain Effects in Mice |
| Q37439130 | Sigma-1 Receptor Agonism Promotes Mechanical Allodynia After Priming the Nociceptive System with Capsaicin |
| Q39158236 | Sigma-1 Receptor Antagonists: A New Class of Neuromodulatory Analgesics |
| Q53647635 | Sigma-1 Receptor and Pain. |
| Q95327470 | Sigma-1 receptor activity in primary sensory neurons is a critical driver of neuropathic pain |
| Q34669463 | Sigma-1 receptor and inflammatory pain. |
| Q33943977 | Sigma-1 receptor antagonism restores injury-induced decrease of voltage-gated Ca2+ current in sensory neurons |
| Q100534366 | Sigma-1 receptor antagonist (BD-1063) potentiates the antinociceptive effect of quercetin in neuropathic pain induced by chronic constriction injury |
| Q37357665 | Sigma-1 receptor expression in sensory neurons and the effect of painful peripheral nerve injury |
| Q87462009 | Sigma-1 receptor inhibition reverses acute inflammatory hyperalgesia in mice: role of peripheral sigma-1 receptors |
| Q55437025 | Sigma-1 receptor: a new player in neuroprotection against chemotherapy-induced peripheral neuropathy. |
| Q34670217 | Sigma-1 receptors and animal studies centered on pain and analgesia |
| Q41292816 | Sigma-1 receptors control immune-driven peripheral opioid analgesia during inflammation in mice. |
| Q39458668 | Sigma1 Pharmacology in the Context of Cancer |
| Q64093881 | Supraspinal and Peripheral, but Not Intrathecal, σR Blockade by S1RA Enhances Morphine Antinociception |
| Q34675713 | The Sigma-1 Receptor as a Pluripotent Modulator in Living Systems. |
| Q54473836 | The antagonistic effect of the sigma 1 receptor ligand (+)-MR200 on persistent pain induced by inflammation. |
| Q51750311 | The calcium-sensitive Sigma-1 receptor prevents cannabinoids from provoking glutamate NMDA receptor hypofunction: implications in antinociception and psychotic diseases. |
| Q40273622 | The selective sigma-1 receptor antagonist E-52862 attenuates neuropathic pain of different aetiology in rats |
| Q43195386 | The σ1 receptor engages the redox-regulated HINT1 protein to bring opioid analgesia under NMDA receptor negative control |
| Q39151193 | Visualizing Nerve Injury in a Neuropathic Pain Model with [18F]FTC-146 PET/MRI. |
Search more.