Differential Synaptic Remodeling by Dopamine in Direct and Indirect Striatal Projection Neurons in Pitx3-/- Mice, a Genetic Model of Parkinson's Disease.

scientific article published on 26 February 2018

Differential Synaptic Remodeling by Dopamine in Direct and Indirect Striatal Projection Neurons in Pitx3-/- Mice, a Genetic Model of Parkinson's Disease. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1523/JNEUROSCI.3184-17.2018
P932PMC publication ID6705913
P698PubMed publication ID29483281

P50authorLuz M SuarezQ64976877
Samuel AlberquillaQ87888153
Jose R García-MontesQ87888157
Rosario MoratallaQ38329789
P2093author name stringSamuel Alberquilla
Jose R García-Montes
Luz M Suarez
P2860cites workSynaptic organisation of the basal gangliaQ24544917
Genetics of Parkinson's diseaseQ26827825
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Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesiaQ30650489
Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkeyQ32061819
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Pitx3 is required for development of substantia nigra dopaminergic neurons.Q34923416
Zooming in on the small: the plasticity of striatal dendritic spines in L-DOPA-induced dyskinesiaQ35574934
Dichotomous anatomical properties of adult striatal medium spiny neuronsQ35607269
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Dopamine Depletion Impairs Bilateral Sensory Processing in the Striatum in a Pathway-Dependent Manner.Q50994519
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Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapsesQ37048087
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L-DOPA Oppositely Regulates Synaptic Strength and Spine Morphology in D1 and D2 Striatal Projection Neurons in DyskinesiaQ37344222
Striatal Neurons Expressing D1 and D2 Receptors are Morphologically Distinct and Differently Affected by Dopamine Denervation in MiceQ37609566
Striatal Signaling in L-DOPA-Induced Dyskinesia: Common Mechanisms with Drug Abuse and Long Term Memory Involving D1 Dopamine Receptor Stimulation.Q37925513
Animal models of L-DOPA-induced dyskinesia: an update on the current optionsQ37998775
PITX3 and risk for Parkinson's disease: a systematic review and meta-analysis.Q38187820
Methamphetamine causes degeneration of dopamine cell bodies and terminals of the nigrostriatal pathway evidenced by silver staining.Q38309143
Local and afferent synaptic pathways in the striatal microcircuitryQ38519415
Loss and remodeling of striatal dendritic spines in Parkinson's disease: from homeostasis to maladaptive plasticity?Q38766091
Pathophysiological signatures of functional connectomics in parkinsonian and dyskinetic striatal microcircuitsQ38898527
Synaptic functions of endocannabinoid signaling in health and diseaseQ39381131
Loss of Homeostasis in the Direct Pathway in a Mouse Model of Asymptomatic Parkinson's Disease.Q39735904
MEF-2 regulates activity-dependent spine loss in striatopallidal medium spiny neurons.Q40817289
Neostriatal cell subtypes and their functional rolesQ41412474
L-DOPA treatment selectively restores spine density in dopamine receptor D2-expressing projection neurons in dyskinetic mice.Q42440010
Nitric oxide synthase inhibition decreases l-DOPA-induced dyskinesia and the expression of striatal molecular markers in Pitx3(-/-) aphakia miceQ42466609
Neurobehavioral Anomalies in the Pitx3/ak Murine Model of Parkinson's Disease and MPTP.Q42483926
Striatal Cholinergic Interneurons Control Motor Behavior and Basal Ganglia Function in Experimental ParkinsonismQ42484046
Coordinated Regulation of Synaptic Plasticity at Striatopallidal and Striatonigral Neurons Orchestrates Motor ControlQ42484851
Electrophysiology of dopamine-denervated striatal neurons. Implications for Parkinson's diseaseQ42497576
Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease modelsQ42508054
Dopamine facilitates dendritic spine formation by cultured striatal medium spiny neurons through both D1 and D2 dopamine receptorsQ42517796
Target selectivity of feedforward inhibition by striatal fast-spiking interneurons.Q42519756
Inactivation of adenosine A2A receptors selectively attenuates amphetamine-induced behavioral sensitizationQ44407165
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neuronsQ44408466
Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neuronsQ44463501
Activation of DREAM (downstream regulatory element antagonistic modulator), a calcium-binding protein, reduces L-DOPA-induced dyskinesias in mice.Q44777361
3,4-dihydroxyphenylalanine reverses the motor deficits in Pitx3-deficient aphakia mice: behavioral characterization of a novel genetic model of Parkinson's disease.Q45281160
Genetic inactivation of dopamine D1 but not D2 receptors inhibits L-DOPA-induced dyskinesia and histone activation.Q45972521
Transcription factor PITX3 gene in Parkinson's diseaseQ46097955
Levodopa-induced dyskinesia in MPTP-treated macaques is not dependent on the extent and pattern of nigrostrial lesioning.Q46608469
PITX3 polymorphism is associated with early onset Parkinson's diseaseQ46638690
ERK phosphorylation and FosB expression are associated with L-DOPA-induced dyskinesia in hemiparkinsonian miceQ46684571
Differential tonic GABA conductances in striatal medium spiny neuronsQ46782245
Dopamine D3 Receptor Modulates l-DOPA-Induced Dyskinesia by Targeting D1 Receptor-Mediated Striatal SignalingQ47637177
Levodopa treatment and dendritic spine pathologyQ48113066
Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesiaQ48124096
Alterations in dendritic morphology of the prefrontal cortical and striatum neurons in the unilateral 6-OHDA-rat model of Parkinson's disease.Q48234700
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectstriatumQ1319792
P304page(s)3619-3630
P577publication date2018-02-26
P1433published inJournal of NeuroscienceQ1709864
P1476titleDifferential Synaptic Remodeling by Dopamine in Direct and Indirect Striatal Projection Neurons in Pitx3-/- Mice, a Genetic Model of Parkinson's Disease
P478volume38

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cites work (P2860)
Q64251973Delayed Spine Pruning of Direct Pathway Spiny Projection Neurons in a Mouse Model of Parkinson's Disease
Q90597369Dopamine Triggers the Maturation of Striatal Spiny Projection Neuron Excitability during a Critical Period
Q92773981Dopaminergic modulation of striatal function and Parkinson's disease
Q58603118Genetic enhancement of Ras-ERK pathway does not aggravate L-DOPA-induced dyskinesia in mice but prevents the decrease induced by lovastatin
Q88498846On the neuronal circuitry mediating L-DOPA-induced dyskinesia
Q100418590Pathway-specific dysregulation of striatal excitatory synapses by LRRK2 mutations
Q64086843Spiny Projection Neuron Dynamics in Toxin and Transgenic Models of Parkinson's Disease
Q89208062Striatal Reinnervation Process after Acute Methamphetamine-Induced Dopaminergic Degeneration in Mice
Q55546568Striatonigral neurons divide into two distinct morphological-physiological phenotypes after chronic L-DOPA treatment in parkinsonian rats.

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