Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo.

scientific article published in January 1994

Site-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID8302604

P2093author name stringFisher C
Woodgett JR
Evan G
Littlewood T
Vousden K
Pulverer BJ
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)59-70
P577publication date1994-01-01
P1433published inOncogeneQ1568657
P1476titleSite-specific modulation of c-Myc cotransformation by residues phosphorylated in vivo
P478volume9

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cites work (P2860)
Q36553239A link between increased transforming activity of lymphoma-derived MYC mutant alleles, their defective regulation by p107, and altered phosphorylation of the c-Myc transactivation domain
Q35000701A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes
Q55481055A polymorphic variant of human c-Myc: Asn11-->Ser.
Q34609728A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins
Q34540779Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells
Q35855075Apparent uncoupling of oncogenicity from fibroblast transformation and apoptosis in a mutant myc gene transduced by feline leukemia virus
Q24676501Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration
Q35310856Autoregulatory suppression of c-Myc by miR-185-3p
Q37214654Burkitt's lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis
Q28265732CD19 is a major B cell receptor-independent activator of MYC-driven B-lymphomagenesis
Q38868844Cdk5-mediated phosphorylation of c-Myc on Ser-62 is essential in transcriptional activation of cyclin B1 by cyclin G1.
Q38836923Chaperone-mediated autophagy prevents cellular transformation by regulating MYC proteasomal degradation.
Q37100081Clinical and Biologic Significance of MYC Genetic Mutations in De Novo Diffuse Large B-cell Lymphoma
Q39610851Complementation of defective colony-stimulating factor 1 receptor signaling and mitogenesis by Raf and v-Src
Q33608508Controlling the Master: Chromatin Dynamics at the MYC Promoter Integrate Developmental Signaling
Q33890400Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc.
Q35140193Diffuse large B-cell lymphoma: insights gained from gene expression profiling
Q33964663Disruption of Myc-tubulin interaction by hyperphosphorylation of c-Myc during mitosis or by constitutive hyperphosphorylation of mutant c-Myc in Burkitt's lymphoma
Q24624069GSK-3: tricks of the trade for a multi-tasking kinase
Q37483862GSK-3β controls NF-kappaB activity via IKKγ/NEMO.
Q40963450GSK3 as a Sensor Determining Cell Fate in the Brain
Q34374129GSK3 takes centre stage more than 20 years after its discovery
Q39801525GSK3beta is a negative regulator of the transcriptional coactivator MAML1.
Q41863937Gain-of-Function Mutations in the Toll-Like Receptor Pathway: TPL2-Mediated ERK1/ERK2 MAPK Activation, a Path to Tumorigenesis in Lymphoid Neoplasms?
Q34692767Glycogen synthase kinase-3beta, mood stabilizers, and neuroprotection
Q34331166Glycosylation of the c-Myc transactivation domain
Q36663762Hierarchical phosphorylation at N-terminal transformation-sensitive sites in c-Myc protein is regulated by mitogens and in mitosis
Q35529775Identification of c-MYC SUMOylation by mass spectrometry
Q36622715Immortalization and transformation of human mammary epithelial cells by a tumor-derived Myc mutant
Q33374007Immortalization of human neural stem cells with the c-myc mutant T58A.
Q33965061Induction of cell cycle progression and acceleration of apoptosis are two separable functions of c-Myc: transrepression correlates with acceleration of apoptosis
Q39937926Inhibition of GSK-3beta promotes survival and proliferation of megakaryocytic cells through a beta-catenin-independent pathway
Q35875611Integrin signalling and the cellular response to ionizing radiation.
Q33836755MYC Deregulation in Primary Human Cancers.
Q39406924MYC Modulation around the CDK2/p27/SKP2 Axis
Q38193043MYC degradation
Q42117553Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer
Q33521691Mechanisms of c-myc degradation by nickel compounds and hypoxia
Q92490663Mission Possible: Advances in MYC Therapeutic Targeting in Cancer
Q39648270Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1.
Q35204486Multiple Ras-dependent phosphorylation pathways regulate Myc protein stability.
Q33997741Myc proteins as therapeutic targets
Q35920494Myc proteins in brain tumor development and maintenance
Q28241326Negative control of the Myc protein by the stress-responsive kinase Pak2
Q37201479Neuroblastoma and MYCN
Q34305847New insights into the mechanisms of embryonic stem cell self-renewal under hypoxia: a multifactorial analysis approach.
Q35554311Novel agent nitidine chloride induces erythroid differentiation and apoptosis in CML cells through c-Myc-miRNAs axis
Q64115578Nuclear ERK: Mechanism of Translocation, Substrates, and Role in Cancer
Q33925043Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
Q37686796PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression
Q33316851Phosphatidylinositol 3-kinase signaling in proliferating cells maintains an anti-apoptotic transcriptional program mediated by inhibition of FOXO and non-canonical activation of NFkappaB transcription factors
Q34801773Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.
Q34743616Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis
Q33742040Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts
Q58114009Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals
Q43240765Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation
Q41493079Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase
Q24538036Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells
Q37184834Repeated electroconvulsive seizure induces c-Myc down-regulation and Bad inactivation in the rat frontal cortex
Q47572600Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma
Q34835596The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
Q37210931The GSK-3/beta-catenin-signalling axis in smooth muscle and its relationship with remodelling
Q36099076The Kaposi's sarcoma-associated herpesvirus LANA protein stabilizes and activates c-Myc
Q33967079The Max network gone mad.
Q41036174The Overexpression of CARM1 Promotes Human Osteosarcoma Cell Proliferation through the pGSK3β/β-Catenin/cyclinD1 Signaling Pathway
Q33963949The c-Myc transactivation domain is a direct modulator of apoptotic versus proliferative signals
Q34373258Therapeutic Targeting of Myc.
Q40427891Transcriptional Regulation: Flipping the Myc switch
Q34066202Transformation of follicular lymphoma to diffuse large-cell lymphoma: alternative patterns with increased or decreased expression of c-myc and its regulated genes
Q37988976Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance
Q35001234What Are the bona fide GSK3 Substrates?
Q28535037Wogonin has multiple anti-cancer effects by regulating c-Myc/SKP2/Fbw7α and HDAC1/HDAC2 pathways and inducing apoptosis in human lung adenocarcinoma cell line A549
Q33962550c-Myc proteolysis by the ubiquitin-proteasome pathway: stabilization of c-Myc in Burkitt's lymphoma cells
Q39576244myc boxes, which are conserved in myc family proteins, are signals for protein degradation via the proteasome

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