IKKalpha is required to maintain skin homeostasis and prevent skin cancer.

scientific article published in September 2008

IKKalpha is required to maintain skin homeostasis and prevent skin cancer. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CCR.2008.07.017
P932PMC publication ID7263012
P698PubMed publication ID18772111
P5875ResearchGate publication ID23238209

P2093author name stringFeng Zhu
John DiGiovanni
Kaoru Kiguchi
Eunmi Park
Susan M Fischer
Xiaojun Xia
Bigang Liu
Yinling Hu
Steve Carbajal
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Epigenetic inactivation of IkappaB Kinase-alpha in oral carcinomas and tumor progressionQ40085455
Chemopreventive and therapeutic efficacy of orally active tyrosine kinase inhibitors in a transgenic mouse model of gallbladder carcinomaQ40390223
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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinaseQ41644582
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IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesisQ42459866
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IKKalpha controls formation of the epidermis independently of NF-kappaB.Q42502421
Keratinocytes blocked in phorbol ester-responsive early stage of terminal differentiation by sarcoma virusesQ42502989
Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogeneQ42823403
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Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomasQ46972187
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A keratin K5Cre transgenic line appropriate for tissue-specific or generalized Cre-mediated recombinationQ47655994
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed proteinQ47767474
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinaseQ48084939
Transgenic coexpression of v-Ha-ras and transforming growth factor alpha increases epidermal hyperproliferation and tumorigenesis and predisposes to malignant conversion via endogenous c-Ha-ras activation.Q53412650
IKKalpha shields 14-3-3sigma, a G(2)/M cell cycle checkpoint gene, from hypermethylation, preventing its silencing.Q53539163
Thymus medulla formation and central tolerance are restored in IKKalpha-/- mice that express an IKKalpha transgene in keratin 5+ thymic epithelial cells.Q53581481
TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2Q57198247
Crosstalk between Keratinocytes and Adaptive Immune Cells in an IκBα Protein-Mediated Inflammatory Disease of the SkinQ57258468
Strain-dependent epithelial defects in mice lacking the EGF receptorQ58326927
Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablationQ59403442
P433issue3
P304page(s)212-225
P577publication date2008-09-01
P1433published inCancer CellQ280018
P1476titleIKKalpha is required to maintain skin homeostasis and prevent skin cancer.
P478volume14