Highlight report: acetaminophen hepatotoxicity.

scientific article

Highlight report: acetaminophen hepatotoxicity. is …
instance of (P31):
scholarly articleQ13442814
editorialQ871232

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P356DOI10.1007/S00204-015-1631-5
P698PubMed publication ID26615526
P5875ResearchGate publication ID285043358

P50authorAhmed GhallabQ43208341
P2860cites workIn vitro - in vivo correlation of gene expression alterations induced by liver carcinogens.Q52889194
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytesQ28566726
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitorsQ30662775
From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug effects.Q33794480
c-Jun N-terminal kinase modulates oxidant stress and peroxynitrite formation independent of inducible nitric oxide synthase in acetaminophen hepatotoxicityQ33912798
Role of caspase-1 and interleukin-1beta in acetaminophen-induced hepatic inflammation and liver injuryQ34088397
"Ecstasy"-induced toxicity in SH-SY5Y differentiated cells: role of hyperthermia and metabolites.Q34381690
Toxicogenomics directory of chemically exposed human hepatocytesQ35423042
Activation of autophagy protects against acetaminophen-induced hepatotoxicityQ35631643
Translational biomarkers of acetaminophen-induced acute liver injuryQ36001451
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Q37121662
Receptor interacting protein kinase 3 is a critical early mediator of acetaminophen-induced hepatocyte necrosis in miceQ37216910
Circulating acylcarnitines as biomarkers of mitochondrial dysfunction after acetaminophen overdose in mice and humansQ37624894
SEURAT-1 liver gold reference compounds: a mechanism-based reviewQ38268013
Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injuryQ38291198
Acetaminophen hepatotoxicity: an updated reviewQ38299336
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approachQ38319756
Critical differences in toxicity mechanisms in induced pluripotent stem cell-derived hepatocytes, hepatic cell lines and primary hepatocytesQ38986528
PI3K signaling mediates diverse regulation of ATF4 expression for the survival of HK-2 cells exposed to cadmiumQ39093024
Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmiumQ39152118
In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid.Q39162099
Hepatic 3D cultures but not 2D cultures preserve specific transporter activity for acetaminophen-induced hepatotoxicityQ39409174
Selective protein covalent binding and target organ toxicityQ41387154
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes.Q42478950
The protective role of NAD(P)H:quinone oxidoreductase 1 on acetaminophen-induced liver injury is associated with prevention of adenosine triphosphate depletion and improvement of mitochondrial dysfunctionQ42704179
The network formation assay: a spatially standardized neurite outgrowth analytical display for neurotoxicity screeningQ43134239
Mode of cell death after acetaminophen overdose in mice: apoptosis or oncotic necrosis?Q43994104
Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophenQ44039549
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytesQ45108825
Acrylamide alters neurotransmitter induced calcium responses in murine ESC-derived and primary neurons.Q50670832
Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.Q51775502
P433issue12
P921main subjecthepatotoxicityQ1349821
paracetamolQ57055
P304page(s)2449-2451
P577publication date2015-12-01
P1433published inArchives of ToxicologyQ635837
P1476titleHighlight report: acetaminophen hepatotoxicity.
P478volume89

Reverse relations

cites work (P2860)
Q46446583Acetaminophen toxicity in rat and mouse hepatocytes in vitro
Q49170889Highlight report: Metabolomics in hepatotoxicity testing
Q49607107Highlight report: physiologically-based modeling of diseased liver tissue

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