Divergent and Stereospecific Routes to Five to Eight-Membered 1,3- and 1,4-Di-Aza-Heterocycles via Ring-Opening Cyclization of Activated Aziridines with Aryl Amines

Divergent and Stereospecific Routes to Five to Eight-Membered 1,3- and 1,4-Di-Aza-Heterocycles via Ring-Opening Cyclization of Activated Aziridines with Aryl Amines is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/SLCT.201602062

P50authorSajan PradhanQ61216125
Navya ChauhanQ61216128
Aditya BhattacharyyaQ53719494
P2093author name stringChandan Kumar Shahi
Manas K. Ghorai
P2860cites workEuropean LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemiaQ26749324
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsQ28842973
The synthesis of chiral annulet 1,4,7-triazacyclononanesQ29038556
Quest for the rings. In silico exploration of ring universe to identify novel bioactive heteroaromatic scaffoldsQ33251011
Selectively N-protected enantiopure 2,5-disubstituted piperazines: avoiding the pitfalls in solid-phase Fukuyama-Mitsunobu cyclizationsQ33405302
Synthesis and Nicotinic Receptor Activity of Chemical Space Analogues of N-(3R)-1-Azabicyclo[2.2.2]oct-3-yl-4-chlorobenzamide (PNU-282,987) and 1,4-Diazabicyclo[3.2.2]nonane-4-carboxylic Acid 4-Bromophenyl Ester (SSR180711)Q34271362
Quetiapine safety in older adults: a systematic literature review.Q35905294
Modular, One-Pot, Sequential Aziridine Ring Opening-S(N)Ar Strategy to 7-, 10-, and 11-Membered Benzo-Fused SultamsQ37091004
Eszopiclone: a review of its use in the treatment of insomniaQ37199768
Conformationally Constrained Peptides as Protein Tyrosine Kinase InhibitorsQ38008730
Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticalsQ38254225
Current drug treatments targeting dopamine D3 receptorQ38876702
Antipsychotic Drug-Induced Somnolence: Incidence, Mechanisms, and ManagementQ38884279
Imidazoline scaffold in medicinal chemistry: a patent review (2012-2015).Q38887608
Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitorsQ39125740
Intramolecular Pd(II)-Catalyzed Aerobic Oxidative Amination of Alkenes: Synthesis of Six-Membered N-HeterocyclesQ42590996
Ring Opening of a Trisubstituted Aziridine With Amines: Regio- and Stereoselective Formation of Substituted 1,2-DiaminesQ42919479
Impact of sildenafil therapy on pulmonary arterial hypertension in adults with congenital heart diseaseQ42968087
Regiodivergent ring opening of chiral aziridinesQ43216700
Enantioselective synthesis of 4,5-dihydropyrroles via domino ring-opening cyclization (DROC) of N-activated aziridines with malononitrileQ44745074
Synthesis and biological activity of novel 1,4-diazepane derivatives as factor Xa inhibitor with potent anticoagulant and antithrombotic activityQ44841498
Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks.Q45973339
A new strategy for the synthesis of 1,4-benzodiazepine derivatives based on the tandem N-alkylation-ring opening-cyclization reactions of methyl 1-arylaziridine-2-carboxylates with N-[2-bromomethyl(phenyl)]trifluoroacetamidesQ46784933
Sigmatropic Rearrangement of Vinyl Aziridines: Expedient Synthesis of Cyclic Sulfoximines from Chiral SulfiniminesQ48162500
Synthesis of Chiral Vicinal Diamines by Silver(I)-Catalyzed Enantioselective Aminolysis of N-TosylaziridinesQ48180437
New ligands with affinity for the alpha4beta2 subtype of nicotinic acetylcholine receptors. Synthesis, receptor binding, and 3D-QSAR modelingQ48524041
LiAlH4 -Induced Selective Ring Rearrangement of 2-(2-Cyanoethyl)aziridines toward 2-(Aminomethyl)pyrrolidines and 3-Aminopiperidines as Eligible Heterocyclic Building BlocksQ49071350
Regiodivergent Intermolecular [3+2] Cycloadditions of Vinyl Aziridines and Allenes: Stereospecific Synthesis of Chiral Pyrrolidines.Q50222410
A BH3 Mimetic for Killing Cancer CellsQ50225641
A New Approach to Non-Coordinating Anions: Lewis Acid Enhancement of Porphyrin Metal Centers in a Zwitterionic Metal-Organic Framework.Q50782769
A modular lead-oriented synthesis of diverse piperazine, 1,4-diazepane and 1,5-diazocane scaffoldsQ52840104
Syntheses of Tetrahydrobenzodiazepines via SN2-Type Ring-Opening of Activated Aziridines with 2-Bromobenzylamine Followed by Copper-Powder-Mediated C−N Bond FormationQ53822321
Syntheses of Imidazo-, Oxa-, and Thiazepine Ring Systems via Ring-Opening of Aziridines/Cu-Catalyzed C–N/C–C Bond FormationQ53822333
Syntheses of Chiral β- and γ-Amino Ethers, Morpholines, and Their Homologues via Nucleophilic Ring-Opening of Chiral Activated Aziridines and AzetidinesQ53822375
Synthesis of 2,6-Disubstituted Piperazines by a Diastereoselective Palladium-Catalyzed Hydroamination ReactionQ57991560
P433issue1
P304page(s)550-556
P577publication date2017-01-03
P1433published inChemistrySelectQ27727586
P1476titleDivergent and Stereospecific Routes to Five to Eight-Membered 1,3- and 1,4-Di-Aza-Heterocycles via Ring-Opening Cyclization of Activated Aziridines with Aryl Amines
P478volume2

Reverse relations

Q53822384Accessing Quinoxalines by Ring-Opening/Cyclization/Detosylation/Aromatization of Activated Aziridines with 2-Bromoanilines: Synthesis of Tyrphostin AG 1296cites workP2860

Search more.