An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential.

scientific article

An Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELL.2018.04.012
P698PubMed publication ID29754815

P50authorEvert BosdrieszQ52609122
Rodrigo Leite de OliveiraQ55948940
Jan H M SchellensQ89824209
Jos BeijnenQ23771643
P2093author name stringRene Bernards
Liqin Wang
Bastiaan Nuijen
Ji-Ying Song
Diede Brunen
Sanne Huijberts
Hugo Horlings
John Zevenhoven
Astrid Bosma
Nora Pencheva
G Tjitske Los-de Vries
P2860cites workEmergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancerQ24604601
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)1413-1425.e14
P577publication date2018-05-10
P1433published inCellQ655814
P1476titleAn Acquired Vulnerability of Drug-Resistant Melanoma with Therapeutic Potential
P478volume173

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cites work (P2860)
Q61807258A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma
Q92528077AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma
Q64998591Anti-tumor effects of the histone deacetylase inhibitor vorinostat on canine urothelial carcinoma cells.
Q58712892Benzylamine and Thenylamine Derived Drugs Induce Apoptosis and Reduce Proliferation, Migration and Metastasis Formation in Melanoma Cells
Q92602356Cellular internalization of bystander nanomaterial induced by TAT-nanoparticles and regulated by extracellular cysteine
Q92765629Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma
Q91866768Disrupting ATF4 Expression Mechanisms Provides an Effective Strategy for BRAF-Targeted Melanoma Therapy
Q97088693Drug mechanism-of-action discovery through the integration of pharmacological and CRISPR screens
Q92133167Drug responses are conserved across patient-derived xenograft models of melanoma leading to identification of novel drug combination therapies
Q90460706Epigenetic Mechanisms of Escape from BRAF Oncogene Dependency
Q96128431Epigenetics and metabolism at the crossroads of stress-induced plasticity, stemness and therapeutic resistance in cancer
Q92130484Exploiting evolutionary steering to induce collateral drug sensitivity in cancer
Q59795693Ezh2 inhibition in Kras-driven lung cancer amplifies inflammation and associated vulnerabilities
Q92544513Fibroblast Growth Factor Receptor Signaling in Skin Cancers
Q92946120HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma
Q60920855HGF/c-MET Signaling in Melanocytes and Melanoma
Q97074415Histone Deacetylase Inhibitors to Overcome Resistance to Targeted and Immuno Therapy in Metastatic Melanoma
Q98771751Histone Deacetylases Inhibit the Snail2-Mediated EMT During Metastasis of Hepatocellular Carcinoma Cells
Q57299883Inhibition of glioblastoma cell proliferation, invasion, and mechanism of action of a novel hydroxamic acid hybrid molecule
Q89001587Lethally high ROS levels thwart resistance
Q91784789Limited Evolutionary Conservation of the Phenotypic Effects of Antibiotic Resistance Mutations
Q91725276Loss of BOP1 confers resistance to BRAF kinase inhibitors in melanoma by activating MAP kinase pathway
Q90043581Melanoma Metabolism: Cell Survival and Resistance to Therapy
Q96304654Metabolic Plasticity of Melanoma Cells and Their Crosstalk With Tumor Microenvironment
Q92627552Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
Q58576103Next-Generation Modeling of Human Cancers
Q92663341Oxidative Stress and Cancer: Chemopreventive and Therapeutic Role of Triphala
Q92235860PDZ-Binding Kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma
Q64250962PMN-MDSCs Enhance CTC Metastatic Properties through Reciprocal Interactions via ROS/Notch/Nodal Signaling
Q91863904Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia
Q89830565Phenotype-based probabilistic analysis of heterogeneous responses to cancer drugs and their combination efficacy
Q57010854SIRT6 haploinsufficiency induces BRAF melanoma cell resistance to MAPK inhibitors via IGF signalling
Q90080013Significance of BRAF Kinase Inhibitors for Melanoma Treatment: From Bench to Bedside
Q89719900Silencing of STAT3 via Peptidomimetic LNP-Mediated Systemic Delivery of RNAi Downregulates PD-L1 and Inhibits Melanoma Growth
Q57172217Taking advantage of drug resistance, a new approach in the war on cancer
Q92663940Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy
Q89658448Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity
Q89638553The "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies"
Q90641451The great escape: tumour cell plasticity in resistance to targeted therapy
Q64068503Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible for maintaining the stemness of breast cancer cells
Q99571031Treatment of Advanced Melanoma: Past, Present and Future
Q90040642Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness
Q59795605Understanding tumor ecosystems by single-cell sequencing: promises and limitations
Q90591550Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
Q90399200Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer
Q58130375With great power comes great vulnerability
Q99547004xCT: A Critical Molecule That Links Cancer Metabolism to Redox Signaling

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