Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage.

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Recombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage. is …
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scholarly articleQ13442814

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P356DOI10.12659/MSM.905700
P932PMC publication ID5870133
P698PubMed publication ID29550832

P2093author name stringWenqian Zhang
Ying Cui
Ran Li
Junling Gao
Xiaohua Jiang
Jianzhong Cui
Kaijie Wang
Yanxia Tian
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Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia-reperfusion injury through suppression of apoptosis and inflammationQ49064432
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Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production.Q54622020
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Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancerQ33864834
The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhageQ34046878
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.Q34184917
Expression, roles, receptors, and regulation of osteopontin in the kidneyQ34434794
Intra-Arterial Transplantation of Allogeneic Mesenchymal Stem Cells Mounts Neuroprotective Effects in a Transient Ischemic Stroke Model in Rats: Analyses of Therapeutic Time Window and Its MechanismsQ35663793
Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis.Q36019726
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Improvement in recovery after experimental intracerebral hemorrhage using a selective cathepsin B and L inhibitorQ37031593
Clinical Features of Liver Cancer with Cerebral HemorrhageQ37032225
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Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cellsQ37455849
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Role of Bcl-2 family proteins and caspases in the regulation of apoptosis.Q37826384
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Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cellsQ40444210
TGF-β1/Smad3 Signaling Pathway Suppresses Cell Apoptosis in Cerebral Ischemic Stroke Rats.Q42325748
Intracerebral hemorrhage-induced neuronal deathQ42503455
α7 nicotinic acetylcholine receptor agonism confers neuroprotection through GSK-3β inhibition in a mouse model of intracerebral hemorrhageQ42606351
Early stages of p53-induced apoptosis are reversibleQ43583217
[Gly14]-Humanin offers neuroprotection through glycogen synthase kinase-3β inhibition in a mouse model of intracerebral hemorrhageQ43898475
The rotarod test: an evaluation of its effectiveness in assessing motor deficits following traumatic brain injuryQ45086104
Neuroprotection by osteopontin in strokeQ45242555
Expression of osteopontin in the rat retina: effects of excitotoxic and ischemic injuriesQ46782094
Recombinant osteopontin attenuates brain injury after intracerebral hemorrhage in mice.Q48213662
Recombinant osteopontin attenuates experimental cerebral vasospasm following subarachnoid hemorrhage in rats through an anti-apoptotic mechanismQ48277213
Role of glycogen synthase kinase-3beta in early depressive behavior induced by mild traumatic brain injury.Q48278662
Osteopontin is elevated in Parkinson's disease and its absence leads to reduced neurodegeneration in the MPTP modelQ48327855
P304page(s)1588-1596
P577publication date2018-03-18
P1433published inMedical Science MonitorQ15756323
P1476titleRecombinant Osteopontin Improves Neurological Functional Recovery and Protects Against Apoptosis via PI3K/Akt/GSK-3β Pathway Following Intracerebral Hemorrhage.
P478volume24

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cites work (P2860)
Q92530078Human amniotic mesenchymal stem cells and their paracrine factors promote wound healing by inhibiting heat stress-induced skin cell apoptosis and enhancing their proliferation through activating PI3K/AKT signaling pathway
Q89934661Hydrogen exerts neuroprotection by activation of the miR-21/PI3K/AKT/GSK-3β pathway in an in vitro model of traumatic brain injury

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