Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection.

scientific article

Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1099/0022-1317-67-3-463
P698PubMed publication ID2419489
P5875ResearchGate publication ID20735598

P2093author name stringA G Dickinson
C F Farquhar
P407language of work or nameEnglishQ1860
P304page(s)463-473
P577publication date1986-03-01
P1433published inJournal of General VirologyQ6295245
P1476titleProlongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection.
P478volume67 ( Pt 3)

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cites work (P2860)
Q36631246Binding of the protease-sensitive form of PrP (prion protein) to sulfated glycosaminoglycan and congo red [corrected]
Q24529092Branched polyamines cure prion-infected neuroblastoma cells
Q57083642Chapter 10 Prions
Q36653932Congo red inhibition of scrapie agent replication
Q39868476Congo red prolongs the incubation period in scrapie-infected hamsters.
Q33847297Deletion of beta-strand and alpha-helix secondary structure in normal prion protein inhibits formation of its protease-resistant isoform
Q28485431Discovery of a novel, monocationic, small-molecule inhibitor of scrapie prion accumulation in cultured sheep microglia and Rov cells
Q37191835Effect of transplantation of bone marrow-derived mesenchymal stem cells on mice infected with prions.
Q33645704Effectiveness of polyene antibiotics in treatment of transmissible spongiform encephalopathy in transgenic mice expressing Syrian hamster PrP only in neurons
Q41753130Enhancement of enterovirus infectivity in vitro by pretreating host cell monolayers with the cationic polymer polyethyleneimine
Q24682427Evaluation of quinacrine treatment for prion diseases
Q36870379Experimental drug treatment of scrapie: A pathogenetic basis for rationale therapeutics
Q34625274Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate?
Q33539797Fatal transmissible amyloid encephalopathy: a new type of prion disease associated with lack of prion protein membrane anchoring
Q40474826Glycosylation-related gene expression in prion diseases: PrPSc accumulation in scrapie infected GT1 cells depends on beta-1,4-linked GalNAc-4-SO4 hyposulfation.
Q34976098Inhibition of Protease-Resistant Prion Protein Accumulation In Vitro by Curcumin
Q33818879Inhibition of prion-protein conversion: a therapeutic tool?
Q36518232Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines
Q40654314Inhibition of scrapie-associated PrP accumulation. Probing the role of glycosaminoglycans in amyloidogenesis
Q39005891Insights from Therapeutic Studies for PrP Prion Disease
Q34304967Interactions and conversions of prion protein isoforms
Q42090343Intraperitoneal infection with scrapie is established within minutes of injection and is non-specifically enhanced by a variety of different drugs
Q64447659Involvement of the immune system in TSE pathogenesis
Q24525199Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation
Q74140633Methods for studying prion protein (PrP) metabolism and the formation of protease-resistant PrP in cell culture and cell-free systems. An update
Q36080838Modulation of Glycosaminoglycans Affects PrPSc Metabolism but Does Not Block PrPSc Uptake.
Q36676179Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy
Q33805383Opposite effects of dextran sulfate 500, the polyene antibiotic MS-8209, and Congo red on accumulation of the protease-resistant isoform of PrP in the spleens of mice inoculated intraperitoneally with the scrapie agent
Q68424144Pathogenesis of hamster scrapie. Adherent splenocytes are associated with relatively high levels of infectivity
Q58277839Polyanion induced fibril growth enables the development of a reproducible assay in solution for the screening of fibril interfering compounds, and the investigation of the prion nucleation site
Q28359788Polysaccharides as antiviral agents: antiviral activity of carrageenan
Q74499436Postexposure prophylaxis against transmissible spongiform encephalopathies: CpG oligodeoxynucleotides in mice
Q34509751Potent antiscrapie activities of degenerate phosphorothioate oligonucleotides
Q60155097Prion Diseases
Q59419884Prion Protein Interaction with Glycosaminoglycan Occurs with the Formation of Oligomeric Complexes Stabilized by Cu(II) Bridges
Q36693364Prion detection by an amyloid seeding assay.
Q35906120Prion diseases--close to effective therapy?
Q37798877Prion protein self-interactions: a gateway to novel therapeutic strategies?
Q48220367Prions and related neurological diseases
Q74452125Prophylactic potential of pentosan polysulphate in transmissible spongiform encephalopathies
Q35990277Rational targeting for prion therapeutics.
Q33722019Sulfated dextrans enhance in vitro amplification of bovine spongiform encephalopathy PrP(Sc) and enable ultrasensitive detection of bovine PrP(Sc).
Q39673524Sulfated glycans and elevated temperature stimulate PrP(Sc)-dependent cell-free formation of protease-resistant prion protein
Q36640586Sulfated polyanion inhibition of scrapie-associated PrP accumulation in cultured cells
Q41987801Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment
Q35652778Suppression of scrapie infection in mice by heteropolyanion 23, dextran sulfate, and some other polyanions
Q30531528Tetracyclines affect prion infectivity
Q35050425The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention
Q36901944Therapeutic approaches for prion disorders
Q35122351Therapeutic approaches to prion diseases.
Q37557690Therapeutic interventions ameliorating prion disease
Q34306678Transmissible spongiform encephalopathies and prion protein interconversions
Q39590279Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie