Recovery of effective hiv-specific cd4+ t-cell activity following antiretroviral therapy in paediatric infection requires sustained suppression of viraemia.

scientific article

Recovery of effective hiv-specific cd4+ t-cell activity following antiretroviral therapy in paediatric infection requires sustained suppression of viraemia. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/QAD.0000000000001844
P932PMC publication ID6039399
P698PubMed publication ID29734220

P50authorPhilippa C MatthewsQ50981209
Pieter JoosteQ58828253
Philip J. R. GoulderQ72618990
Emily AdlandQ79069274
M MuenchhoffQ87288667
Gareth Tudor-WilliamsQ95647857
Alice SwordyQ113126433
P2093author name stringLeana Laker
Luisa Mori
Anna Csala
Masa Mori
P2860cites workMolecular and cellular insights into T cell exhaustionQ26800047
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Two subsets of memory T lymphocytes with distinct homing potentials and effector functionsQ28146072
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HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cellsQ29616205
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progressionQ29618956
Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccinationQ33884084
Young HIV-infected adults are at greater risk for medication nonadherenceQ33962940
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Absence of detectable HIV-1 viremia after treatment cessation in an infantQ34379777
Effect of caregivers' depression and alcohol use on child antiretroviral adherence in South AfricaQ35245327
Incomplete immune reconstitution despite virologic suppression in HIV-1 infected children and adolescentsQ35338750
Population-based hematologic and immunologic reference values for a healthy Ugandan populationQ35542336
Human immunodeficiency virus-specific CD8+ T-cell activity is detectable from birth in the majority of in utero-infected infantsQ36315692
Emergence of polyfunctional CD8+ T cells after prolonged suppression of human immunodeficiency virus replication by antiretroviral therapyQ36498230
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HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF-CO10 paediatric cohort: a case reportQ40834710
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Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological agingQ49167316
Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies.Q51998139
Immune repopulation after HAART in previously untreated HIV-1-infected children. Paediatric European Network for Treatment of AIDS (PENTA) Steering Committee.Q52027512
HIV: Shock and kill.Q55056512
Long-Term Effects of Highly Active Antiretroviral Therapy in Pretreated, Vertically HIV Type 1-Infected Children: 6 Years of Follow-UpQ57276223
Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infectionQ61928277
Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?Q71840957
HIV-1-specific cytotoxic T lymphocyte responses in the first year of lifeQ72896097
HIV-1 replication increases HIV-specific CD4+ T cell frequencies but limits proliferative capacity in chronically infected childrenQ73419672
Gag-specific CD4+ T-cell responses are associated with virological control of paediatric HIV-1 infectionQ83906060
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectanti-retroviral agentQ50430310
P304page(s)1413-1422
P577publication date2018-05-03
P1433published inAIDSQ4651863
P1476titleRecovery of effective hiv-specific cd4+ t-cell activity following antiretroviral therapy in paediatric infection requires sustained suppression of viraemia.
P478volume32

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cites work (P2860)
Q64229951Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children
Q99561493Evaluation of HIV-specific T-cell responses in HIV-infected older patients with controlled viremia on long-term antiretroviral therapy
Q92879601High rate of rubella seronegativity in perinatally-infected HIV women of childbearing age: A case-control study