Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody

scientific article published on January 25, 1993

Topology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody is …
instance of (P31):
scholarly articleQ13442814

External links are
P953full work available at URLhttps://doi.org/10.1016/s0021-9258(18)53923-5
http://intl.jbc.org/cgi/content/abstract/268/3/1792
https://api.elsevier.com/content/article/PII:S0021925818539235?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0021925818539235?httpAccept=text/xml
P698PubMed publication ID7678410

P2093author name stringT. Tsuruo
V. Ling
E. Georges
P2860cites workCancer ResearchQ326097
Isolation and expression of a complementary DNA that confers multidrug resistanceQ24295219
Mammalian multidrug resistance gene: complete cDNA sequence indicates strong homology to bacterial transport proteinsQ28116625
Sequence of mdr3 cDNA encoding a human P-glycoproteinQ28284009
9-Fluorenylmethoxycarbonyl amino-protecting groupQ29040678
Analysis of membrane and surface protein sequences with the hydrophobic moment plotQ29618183
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sitesQ33832954
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle proteinQ34040187
Three-dimensional structure of an antibody-antigen complexQ34366479
Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.Q34559072
Expression of a multidrug-resistance gene in human tumors and tissuesQ34586576
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastineQ34620070
Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequenceQ34707825
Use of peptide synthesis to probe viral antigens for epitopes to a resolution of a single amino acidQ36264118
Slow permeation of organic cations in acetylcholine receptor channelsQ36409470
Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodiesQ37403387
Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodiesQ37660701
P-glycoprotein: multidrug-resistance and a superfamily of membrane-associated transport proteins.Q38367807
Dimerization of the P-glycoprotein in membranesQ41721905
Further characterization of the human adrenal-derived P-glycoprotein recognized by monoclonal antibody MRK 16 reacting with only human P-glycoproteinQ41759662
Detection of P-glycoprotein in multidrug-resistant cell lines by monoclonal antibodiesQ42812351
Determination of membrane antigens by a covalent crosslinking method with monoclonal antibodiesQ43844147
Strategies for epitope analysis using peptide synthesis.Q54133512
Sex-dependent and independent expression of the P-glycoprotein isoforms in Chinese hamster.Q54311769
Color test for detection of free terminal amino groups in the solid-phase synthesis of peptidesQ56390180
A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesisQ56834003
Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistanceQ59050857
Three-dimensional structure of an antigen-antibody complex at 2.8 A resolutionQ68969863
Expression of the mdr (P-glycoprotein) gene in Chinese hamster digestive tractsQ69915351
IUPAC-IUB Commission on Biochemical Nomenclature. A one-letter notation for amino acid sequences. Tentative rulesQ72454159
Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell LinesQ72561176
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
monoclonal antibodyQ422248
P304page(s)1792-1798
P577publication date1993-01-01
1993-01-25
P1433published inJournal of Biological ChemistryQ867727
P1476titleTopology of P-glycoprotein as determined by epitope mapping of MRK-16 monoclonal antibody
P478volume268

Reverse relations

cites work (P2860)
Q40534105Antibodies in the study of multiple drug resistance
Q33851297Brain microvascular P-glycoprotein and a revised model of multidrug resistance in brain
Q35179585Cell biological mechanisms of multidrug resistance in tumors
Q30427419Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region
Q35604412Conformational analysis of human ATP-binding cassette transporter ABCB1 in lipid nanodiscs and inhibition by the antibodies MRK16 and UIC2.
Q36910362Coupled translocation events generate topological heterogeneity at the endoplasmic reticulum membrane
Q73936254Detection of recombinant P-glycoprotein in multidrug resistant cultured cells
Q37405445Effects of putative catalytic base mutation E211Q on ABCG2-mediated methotrexate transport
Q34969885Glutamine residues in Q-loops of multidrug resistance protein MRP1 contribute to ATP binding via interaction with metal cofactor
Q58236950Immunogold localisation of P-glycoprotein in supported lipid bilayers by transmission electron microscopy and atomic force microscopy
Q73041298In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients
Q72893070Influence of rat strain on P-glycoprotein expression in cultured hepatocytes
Q28386214Lipids in the assembly of membrane proteins and organization of protein supercomplexes: implications for lipid-linked disorders
Q39095238Lymphokine-activated killer cell susceptibility and adhesion molecule expression of multidrug resistant breast carcinoma
Q58707545Mapping discontinuous epitopes for MRK-16, UIC2 and 4E3 antibodies to extracellular loops 1 and 4 of human P-glycoprotein
Q40535310Molecular analysis of the multidrug transporter
Q37323494Molecular analysis of the multidrug transporter, P-glycoprotein
Q41340654New flow cytometric method for detection of minimally expressed multidrug resistance P-glycoprotein on normal and acute leukemia cells using biotinylated MRK16 and streptavidin-RED670 conjugate
Q40425461P-glycoprotein expression and regulation. Age-related changes and potential effects on drug therapy
Q36712329P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity
Q38205719The ability of molecular docking to unravel the controversy and challenges related to P-glycoprotein--a well-known, yet poorly understood drug transporter
Q36826007Topology of MDR1-P-glycoprotein as indicated by epitope mapping of monoclonal antibodies to human MDR cells
Q41973592Topology prediction of membrane proteins

Search more.