ARF-mediated SUMOylation of Apak antagonizes ubiquitylation and promotes its nucleolar accumulation to inhibit 47S pre-rRNA synthesis.

scientific article

ARF-mediated SUMOylation of Apak antagonizes ubiquitylation and promotes its nucleolar accumulation to inhibit 47S pre-rRNA synthesis. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/JMCB/MJV010
P8608Fatcat IDrelease_3hsythboxrbprm4ptq3zqp3biu
P698PubMed publication ID25691462

P2093author name stringLin Yuan
Fuchu He
Guichun Xing
Lingqiang Zhang
Lihua Yang
Shan Wang
Hua Guo
Siying Wang
Xue Kong
P2860cites workB23 and ARF: friends or foes?Q36582063
Sumoylation and regulation of cardiac gene expressionQ37097348
RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis.Q38906649
The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I.Q39698267
KRAB-type zinc-finger protein Apak specifically regulates p53-dependent apoptosis.Q39859206
UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery.Q40480663
Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.Q40613625
Nucleolar Arf tumor suppressor inhibits ribosomal RNA processingQ40666241
P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2.Q40701686
Formation of the androgen receptor transcription complexQ40740525
Growth factor signaling regulates elongation of RNA polymerase I transcription in mammals via UBF phosphorylation and r-chromatin remodelingQ42804681
MDM2-ARF complex regulates p53 sumoylationQ44549004
Nucleolar proteome dynamicsQ21735921
The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complexQ24293286
ARF-dependent regulation of ATM and p53 associated KZNF (Apak) protein activity in response to oncogenic stressQ24296257
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressorQ24306428
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathwaysQ24321528
Modification with SUMO. A role in transcriptional regulationQ24534589
Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activationQ24564177
Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23Q24629309
A non-tumor suppressor role for basal p19ARF in maintaining nucleolar structure and functionQ24642046
P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2Q24650492
A multistep, GTP-driven mechanism controlling the dynamic cycling of nucleosteminQ24678915
Characterization of the Localization and Proteolytic Activity of the SUMO-specific Protease, SENP1Q27863778
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognitionQ27865256
Protein group modification and synergy in the SUMO pathway as exemplified in DNA repairQ27939387
SUMO and ubiquitin in the nucleus: different functions, similar mechanisms?Q28280175
Targeting WW domains linker of HECT-type ubiquitin ligase Smurf1 for activation by CKIP-1Q28287877
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2.Q33889383
Stress signals utilize multiple pathways to stabilize p53Q33963268
Human tumor suppressor p14ARF negatively regulates rRNA transcription and inhibits UBF1 transcription factor phosphorylation.Q33998894
SP-RING for SUMO: new functions bloom for a ubiquitin-like proteinQ34094595
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stressesQ34275810
Natural products in anticancer therapy.Q34441101
Conventional and nonconventional roles of the nucleolusQ34813102
Signaling to p53: ribosomal proteins find their way.Q35206381
Apak competes with p53 for direct binding to intron 1 of p53AIP1 to regulate apoptosis.Q35874908
Functional and physical interactions of the ARF tumor suppressor with p53 and Mdm2Q36174385
Cellular stress and nucleolar functionQ36276746
P433issue2
P921main subjectprotein sumoylationQ3503705
ubiquitinationQ33059483
P304page(s)154-167
P577publication date2015-02-17
P1433published inJournal of Molecular Cell BiologyQ2456339
P1476titleARF-mediated SUMOylation of Apak antagonizes ubiquitylation and promotes its nucleolar accumulation to inhibit 47S pre-rRNA synthesis.
P478volume7

Search more.