Phospholipase C epsilon plays a suppressive role in incidence of colorectal cancer.

scientific article

Phospholipase C epsilon plays a suppressive role in incidence of colorectal cancer. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12032-011-9981-1
P698PubMed publication ID21667163

P2093author name stringXiaoliang Wang
Zhihai Peng
Junwei Fan
Yinxue Yang
Chongzhi Zhou
Huamei Tang
Guoqiang Qiu
Dongwang Yan
Tonghai Xing
P2860cites workA novel bifunctional phospholipase c that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathwayQ24290368
Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by RasQ24290369
Novel type of Ras effector interaction established between tumour suppressor NORE1A and Ras switch IIQ24309371
Role of the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signalingQ28200783
Targeting RAS signalling pathways in cancer therapyQ28201363
Phospholipase C(epsilon): a novel Ras effectorQ28348875
RASSF6 is a novel member of the RASSF family of tumor suppressorsQ28509722
Regulation of phospholipase C isozymes by ras superfamily GTPasesQ34482971
Phospholipase Cepsilon is a nexus for Rho and Rap-mediated G protein-coupled receptor-induced astrocyte proliferationQ36024090
Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancerQ36818078
Rassf family of tumor suppressor polypeptides.Q37353443
Recent insights into the pathogenesis of colorectal cancer.Q37604836
Epigenetic inactivation of RASSF2 in oral squamous cell carcinoma.Q40009864
Ras-association domain family protein 6 induces apoptosis via both caspase-dependent and caspase-independent pathwaysQ40157708
The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilonQ40304833
Screening of new tumor suppressor genes in sporadic colorectal cancer patients.Q45692871
Identification of PLC210, a Caenorhabditis elegans phospholipase C, as a putative effector of Ras.Q47069041
New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.Q55033068
NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancersQ72992695
P433issue2
P921main subjectcolorectal cancerQ188874
P304page(s)1051-1058
P577publication date2011-06-11
P1433published inMedical OncologyQ2152666
P1476titlePhospholipase C epsilon plays a suppressive role in incidence of colorectal cancer.
P478volume29

Reverse relations

cites work (P2860)
Q84475338Association of 10q23 with colorectal cancer in a Chinese population
Q44845225Association of potentially functional genetic variants of PLCE1 with gallbladder cancer susceptibility in north Indian population.
Q38429304Comprehensive bioinformatics analysis of the mRNA profile of PLCE1 knockdown in esophageal squamous cell carcinoma
Q47313215Comprehensive bioinformation analysis of the miRNA of PLCE1 knockdown in esophageal squamous cell carcinoma
Q37225710Decreased MALL expression negatively impacts colorectal cancer patient survival
Q44037227Elevated expression patterns and tight correlation of the PLCE1 and NF-κB signaling in Kazakh patients with esophageal carcinoma
Q47652668Functional role of PLCE1 intronic insertion variant associated with susceptibility to esophageal squamous-cell carcinoma.
Q51660596Genetic Variations in Phospholipase C-epsilon 1 (PLCE1) and Susceptibility to Colorectal Cancer Risk.
Q44539939Genetic association of PLCE1, C11orf92-C11orf93, and NOC3L with colorectal cancer risk in the Han population
Q36412273Genetic variants at 6p21, 10q23, 16q21 and 22q12 are associated with esophageal cancer risk in a Chinese Han population
Q36284993Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations
Q50003353Identification of Staphylococcus aureus α-hemolysin as a protein drug that is secreted by anticancer bacteria and rapidly kills cancer cells
Q35014668Increased risk of developing digestive tract cancer in subjects carrying the PLCE1 rs2274223 A>G polymorphism: evidence from a meta-analysis
Q37530861Low PLCE1 levels are correlated with poor prognosis in hepatocellular carcinoma
Q47155512MicroRNA-34a functions as a tumor suppressor by directly targeting oncogenic PLCE1 in Kazakh esophageal squamous cell carcinoma
Q39154242Overexpression of PLCE1 in Kazakh esophageal squamous cell carcinoma: implications in cancer metastasis and aggressiveness
Q34393274PLCE1 mRNA and protein expression and survival of patients with esophageal squamous cell carcinoma and gastric adenocarcinoma
Q33710068PLCE1 polymorphisms and expression combined with serum AFP level predicts survival of HBV-related hepatocellular carcinoma patients after hepatectomy
Q50881464PLCE1 rs2274223 A>G polymorphism and cancer risk: a meta-analysis.
Q39001251PLCE1 suppresses p53 expression in esophageal cancer cells
Q92425204PLCε regulates prostate cancer mitochondrial oxidative metabolism and migration via upregulation of Twist1
Q36093239Phosphoinositide-specific phospholipase C in health and disease
Q34735909Phospholipase C epsilon 1 (PLCE1) haplotypes are associated with increased risk of gastric cancer in Kashmir Valley
Q34016649Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome
Q34218363Phospholipase Cδ1 induces E-cadherin expression and suppresses malignancy in colorectal cancer cells
Q34193026Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population
Q84490516Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population
Q54194242Role of novel and GWAS originated PLCE1 genetic variants in susceptibility and prognosis of esophageal cancer patients in northern Indian population.
Q60960101Single Nucleotide Polymorphisms in for Cancer Risk of Different Types: A Meta-Analysis
Q36738971Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma
Q36412258The association between phospholipase C epsilon gene (PLCE1) polymorphisms and colorectal cancer risk in a Chinese Han population: a case-control study
Q37738063The controversial role of phospholipase C epsilon (PLCε) in cancer development and progression
Q37660073Tumor suppressor role of phospholipase C epsilon in Ras-triggered cancers

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