Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice.

scientific article

Functional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.2013.266924
P932PMC publication ID3948568
P698PubMed publication ID24396058

P2093author name stringHelga Vitzthum
Heimo Ehmke
Anika Seniuk
Hannah Hetz
Laura Helene Schulte
Maxie Luise Müller
P2860cites workAngiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathwayQ24648927
Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Mechanisms of disease: WNK-ing at the mechanism of salt-sensitive hypertensionQ28254512
Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosteroneQ28290886
Effects of dietary K on cell-surface expression of renal ion channels and transportersQ28567696
A SPAK isoform switch modulates renal salt transport and blood pressureQ28586855
Aldosterone induces rapid apical translocation of ENaC in early portion of renal collecting system: possible role of SGK.Q33938102
Molecular genetics of human blood pressure variationQ34377106
SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstrictionQ34457030
Increased blood pressure during potassium depletion in normotensive men.Q34488423
Normotensive salt sensitivity: effects of race and dietary potassiumQ34490739
Sodium and potassium in the pathogenesis of hypertensionQ34627313
WNK1 kinase isoform switch regulates renal potassium excretion.Q34694518
Recent advances in distal tubular potassium handlingQ34784068
Control of aldosterone secretion: a model for convergence in cellular signaling pathwaysQ35715226
Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent processQ35974133
Role of the WNK-activated SPAK kinase in regulating blood pressureQ36039159
Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephronQ36200312
Multigene kinase network, kidney transport, and salt in essential hypertensionQ36862737
Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.Q37337316
The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transportQ37714173
The WNK kinase network regulating sodium, potassium, and blood pressureQ37857562
Aldosterone paradox: differential regulation of ion transport in distal nephron.Q37864472
Independent regulation of Na+ and K+ balance by the kidney.Q37951339
The kidney and hypertension: lessons from mouse modelsQ38000611
Effects of angiotensin II on kinase-mediated sodium and potassium transport in the distal nephronQ38060969
Reversible Ponceau staining as a loading control alternative to actin in Western blotsQ39731848
Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathwayQ41966666
Potassium depletion and salt sensitivity in essential hypertensionQ43633930
Gene expression of prostanoid forming enzymes along the rat nephronQ44173341
Targeted disruption of the Wnk4 gene decreases phosphorylation of Na-Cl cotransporter, increases Na excretion and lowers blood pressureQ46146557
Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channelQ48893193
Dietary electrolyte-driven responses in the renal WNK kinase pathway in vivo.Q50646202
A simplified method for isolation of large numbers of defined nephron segmentsQ73856939
Regulation of WNK1 kinase by extracellular potassiumQ82605409
Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in miceQ86215259
P433issue5
P407language of work or nameEnglishQ1860
P1104number of pages19
P304page(s)1139-1157
P577publication date2014-01-06
P1433published inJournal of PhysiologyQ7743612
P1476titleFunctional coupling of renal K+ and Na+ handling causes high blood pressure in Na+ replete mice.
P478volume592

Reverse relations

cites work (P2860)
Q39125105Cardiovascular benefits associated with higher dietary K+ vs. lower dietary Na+: evidence from population and mechanistic studies
Q91978230Clinical importance of potassium intake and molecular mechanism of potassium regulation
Q38307745Dietary potassium and the renal control of salt balance and blood pressure
Q42371179Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport.
Q52975643Distal convoluted tubule.
Q47707757Diuretic Treatment in Heart Failure
Q51616845Extracellular K+ rapidly controls NaCl cotransporter phosphorylation in the native distal convoluted tubule by Cl- -dependent and independent mechanisms.
Q48094444H,K-ATPase type 2 contributes to salt-sensitive hypertension induced by K(+) restriction.
Q54981482Intracellular Chloride and Scaffold Protein Mo25 Cooperatively Regulate Transepithelial Ion Transport through WNK Signaling in the Malpighian Tubule.
Q38543656Kelch-like 3/Cullin 3 ubiquitin ligase complex and WNK signaling in salt-sensitive hypertension and electrolyte disorder
Q35027258Mechanisms of renal control of potassium homeostasis in complete aldosterone deficiency
Q39137286Potassium Homeostasis: The Knowns, the Unknowns, and the Health Benefits
Q48000331Potassium Sensing by Renal Distal Tubules Requires Kir4.1.
Q41643544Potassium Supplementation Prevents Sodium Chloride Cotransporter Stimulation During Angiotensin II Hypertension.
Q36746113Potassium and Its Discontents: New Insight, New Treatments
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Q38838019Potassium: friend or foe?
Q36821637Renal mineralocorticoid receptor and electrolyte homeostasis
Q33853484Renal sodium handling and sodium sensitivity
Q49365573Role of ClC-K and barttin in low potassium-induced sodium chloride cotransporter activation and hypertension in mouse kidney.
Q26741611Serum and Glucocorticoid Regulated Kinase 1 in Sodium Homeostasis
Q38752148Severe hyperkalemia is rescued by low-potassium diet in renal βENaC-deficient mice.
Q91893550The WNK signaling pathway and salt-sensitive hypertension
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Q38256634The multiple roles of pendrin in the kidney
Q39698346Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis
Q89164276WNK-SPAK/OSR1 signaling: lessons learned from an insect renal epithelium
Q35933690Why Your Mother Was Right: How Potassium Intake Reduces Blood Pressure.