Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer

scientific article published in January 2012

Studies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12013-011-9257-6
P698PubMed publication ID21910030

P2093author name stringBinbin Cui
Yanmei Yang
Ji Tao
P2860cites workWeakening link to colorectal cancer?Q57006460
Essential role for the p110 isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemiaQ57220263
Isoform selective phosphoinositide 3-kinase gamma and delta inhibitors and their therapeutic potentialQ24329100
PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodiesQ27851465
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Essential role for the p110delta phosphoinositide 3-kinase in the allergic responseQ28288981
Cancer statistics, 2009Q29547625
PI3K pathway alterations in cancer: variations on a themeQ29615530
Targeting the phosphoinositide 3-kinase pathway in cancerQ29615809
The emerging mechanisms of isoform-specific PI3K signallingQ29617954
Effective surgical adjuvant therapy for high-risk rectal carcinomaQ33387384
Rules for making human tumor cellsQ34159004
The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cellsQ34234737
Oncogenic transformation induced by the p110beta, -gamma, and -delta isoforms of class I phosphoinositide 3-kinaseQ34335162
Cancer-specific mutations in PIK3CA are oncogenic in vivoQ34335169
The PTEN-PI3K pathway: of feedbacks and cross-talksQ34828662
Phosphoinositide 3-kinase signalling--which way to target?Q35181798
Oncogenic PI3K deregulates transcription and translationQ36337966
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.Q36751486
PTEN-deficient cancers depend on PIK3CB.Q36861839
PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancerQ37137091
Can exercise ameliorate the increased risk of cardiovascular disease and diabetes associated with ADT?Q37145834
Drug discovery approaches targeting the PI3K/Akt pathway in cancerQ37270455
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinaseQ38326223
Isoform-specific phosphoinositide 3-kinase inhibitors exert distinct effects in solid tumorsQ39747551
Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.Q40012035
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.Q41791633
Isoform-selective phosphoinositide 3'-kinase inhibitors inhibit CXCR4 signaling and overcome stromal cell-mediated drug resistance in chronic lymphocytic leukemia: a novel therapeutic approachQ42191925
Functional analysis of PIK3CA gene mutations in human colorectal cancerQ42814030
A specific function for phosphatidylinositol 3-kinase alpha (p85alpha-p110alpha) in cell survival and for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in de novo DNA synthesis of human colon carcinoma cellsQ42834760
Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation.Q42948871
Frequent alterations of the PI3K/AKT/mTOR pathways in hereditary nonpolyposis colorectal cancerQ43280944
BCR-ABL regulates phosphatidylinositol 3-kinase-p110gamma transcription and activation and is required for proliferation and drug resistance.Q46807683
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)KgammaQ47832177
Clinicopathological significance of PTEN loss and the phosphoinositide 3-kinase/Akt pathway in sporadic colorectal neoplasms: is PTEN loss predictor of local recurrence?Q51704738
Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancersQ51717752
PI3K regulatory subunits lose control in cancer.Q54705697
Genetic alterations of phosphoinositide 3-kinase subunit genes in human glioblastomas.Q55471652
P433issue1
P921main subjectcolorectal cancerQ188874
P304page(s)47-54
P577publication date2012-01-01
P1433published inCell Biochemistry and BiophysicsQ15755135
P1476titleStudies on the expression patterns of class I PI3K catalytic subunits and its prognostic significance in colorectal cancer
P478volume62

Reverse relations

cites work (P2860)
Q54397311Abelson interactor 1 (Abi1) in colorectal cancer. From synaptic plasticity to tumor cell migration
Q57024518Biochemical significance of limonene and its metabolites: future prospects for designing and developing highly potent anticancer drugs
Q54188074Expression and clinicopathological significance of EED, SUZ12 and EZH2 mRNA in colorectal cancer
Q44123472Expression and clinicopathological significance of Mel-18 mRNA in colorectal cancer
Q50047956Hypoxia induces pulmonary arterial fibroblast proliferation, migration, differentiation and vascular remodeling via the PI3K/Akt/p70S6K signaling pathway
Q53136255Induction of apoptosis by D-limonene is mediated by inactivation of Akt in LS174T human colon cancer cells
Q34732954PIK3CA and PIK3CB expression and relationship with multidrug resistance in colorectal carcinoma
Q38805492PIK3CA and PIK3CB silencing by RNAi reverse MDR and inhibit tumorigenic properties in human colorectal carcinoma
Q34552147Phosphatidylinositol 3-kinase CB association with preoperative radiotherapy response in rectal adenocarcinoma
Q33776641Recent advances in the use of PI3K inhibitors for glioblastoma multiforme: current preclinical and clinical development

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