Omentin inhibits osteoblastic differentiation of calcifying vascular smooth muscle cells through the PI3K/Akt pathway

scientific article published on November 17, 2010

Omentin inhibits osteoblastic differentiation of calcifying vascular smooth muscle cells through the PI3K/Akt pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S00726-010-0800-3
P8608Fatcat IDrelease_zl7gezgyu5amlg4ar43khfiumm
P953full work available at URLhttp://link.springer.com/content/pdf/10.1007/s00726-010-0800-3.pdf
http://link.springer.com/article/10.1007/s00726-010-0800-3/fulltext.html
http://link.springer.com/content/pdf/10.1007/s00726-010-0800-3
P698PubMed publication ID21082206

P2093author name stringPing-Li Xie
Si-Yuan Tang
Yu-Lin Ma
Xin-Yun Duan
P2860cites workIdentification of omentin as a novel depot-specific adipokine in human adipose tissue: possible role in modulating insulin actionQ24307700
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Apelin and its receptor are expressed in human osteoblastsQ28303722
Circulating omentin concentration increases after weight lossQ33810842
TGF-beta 1 and 25-hydroxycholesterol stimulate osteoblast-like vascular cells to calcify.Q34145009
Waist circumference and not body mass index explains obesity-related health riskQ34301193
Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissueQ34480822
Estrogen receptor α36 mediates a bone-sparing effect of 17β-estrodiol in postmenopausal women.Q35229925
Vascular calcification: mechanisms and clinical ramificationsQ35779458
Adiponectin: Identification, physiology and clinical relevance in metabolic and vascular diseaseQ36095122
Therapeutic perspectives of adipocytokinesQ36161243
CB2 cannabinoid receptor agonists attenuate TNF-alpha-induced human vascular smooth muscle cell proliferation and migrationQ36416330
Relationship between CT anthropometric measurements, adipokines and abdominal aortic calcificationQ36528606
Adipose tissue-derived factors: impact on health and diseaseQ36631232
Vascular calcification: pathobiological mechanisms and clinical implicationsQ36649449
Abdominal obesity and metabolic syndromeQ36682671
Adipose tissue and atherosclerosis: exploring the connectionQ36736914
Clinical, cellular, and molecular aspects of arterial calcificationQ36837874
The emerging role of adipokines as mediators of cardiovascular function: physiologic and clinical perspectives.Q37005382
Adiponectin: an updateQ37028030
Adiponectin and its role in cardiovascular diseasesQ37108345
PI3K/Akt: getting it right mattersQ37310202
A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humansQ37452331
Deoxypodophyllotoxin, flavolignan, from Anthriscus sylvestris Hoffm. inhibits migration and MMP-9 via MAPK pathways in TNF-alpha-induced HASMC.Q38497884
Association of visceral adipose tissue with incident myocardial infarction in older men and women: the Health, Aging and Body Composition StudyQ39696871
Suppressive effect of dexamethasone on TIMP-1 production involves murine osteoblastic MC3T3-E1 cell apoptosis.Q39821290
L-carnitine protects against apoptosis of murine MC3T3-E1 osteoblastic cellsQ40074036
Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways.Q40207646
Bone morphogenetic protein expression in human atherosclerotic lesions.Q40304303
Association of multiple risk factors and insulin resistance with increased prevalence of asymptomatic coronary artery disease by an electron-beam computed tomographic studyQ40672428
Development and characterization of a conditionally transformed adult human osteoblastic cell lineQ41195039
Taurine restores Axl/Gas6 expression in vascular smooth muscle cell calcification modelQ43208595
Abdominal aortic calcific deposits are an important predictor of vascular morbidity and mortalityQ43546639
Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and womenQ44291205
Visceral Adipose Tissue Cutoffs Associated With Metabolic Risk Factors for Coronary Heart Disease in WomenQ44418804
Insulin sensitivity, insulin secretion, and abdominal fat: the Insulin Resistance Atherosclerosis Study (IRAS) Family StudyQ44599790
Visceral fat in hypertension: influence on insulin resistance and beta-cell functionQ44985642
Insulin-like growth factor-I regulates proliferation and osteoblastic differentiation of calcifying vascular cells via extracellular signal-regulated protein kinase and phosphatidylinositol 3-kinase pathwaysQ45251412
cAMP stimulates osteoblast-like differentiation of calcifying vascular cells. Potential signaling pathway for vascular calcification.Q45996887
Abdominal obesity and coronary artery calcification in young adults: the Coronary Artery Risk Development in Young Adults (CARDIA) StudyQ46279611
Adiponectin antagonizes stimulatory effect of tumor necrosis factor-alpha on vascular smooth muscle cell calcification: regulation of growth arrest-specific gene 6-mediated survival pathway by adenosine 5'-monophosphate-activated protein kinaseQ46823956
Axl/phosphatidylinositol 3-kinase signaling inhibits mineral deposition by vascular smooth muscle cells.Q50707613
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study.Q51469352
Double-edged relationship between adiposity and coronary artery calcification in type 1 diabetes.Q53444724
Omentin plasma levels and gene expression are decreased in obesity.Q55043420
Body morphology differentially predicts coronary calciumQ57565715
Tumor necrosis factor-alpha promotes in vitro calcification of vascular cells via the cAMP pathwayQ73209080
Apelin suppresses apoptosis of human osteoblastsQ79394757
Gas6/Axl-PI3K/Akt pathway plays a central role in the effect of statins on inorganic phosphate-induced calcification of vascular smooth muscle cellsQ79464851
Insulin-like effects of visfatin on human osteoblastsQ79882744
Cryptotanshinone from Salvia miltiorrhiza BUNGE has an inhibitory effect on TNF-alpha-induced matrix metalloproteinase-9 production and HASMC migration via down-regulated NF-kappaB and AP-1Q80339951
Coronary calcification improves cardiovascular risk prediction in the elderlyQ80357431
Does waist circumference alone explain obesity-related health risk?Q80475139
Low plasma adiponectin levels predict progression of coronary artery calcificationQ81378144
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcell differentiationQ210861
signal transductionQ828130
P304page(s)1223-1231
P577publication date2010-11-17
P1433published inAmino AcidsQ15757015
P1476titleOmentin inhibits osteoblastic differentiation of calcifying vascular smooth muscle cells through the PI3K/Akt pathway
P478volume41

Reverse relations

cites work (P2860)
Q38014474Adipokines and the cardiovascular system: mechanisms mediating health and disease
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Q39390964Adipose Tissue-Derived Omentin-1 Function and Regulation
Q34651892Cardioprotective properties of omentin-1 in type 2 diabetes: evidence from clinical and in vitro studies.
Q53800814Counteractive effects of omentin-1 against atherogenesis†.
Q53335886Implication of circulating omentin-1 level on the arterial stiffening in type 2 diabetes mellitus.
Q36314694MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification
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Q36765609Omentin-1 Stimulates Human Osteoblast Proliferation through PI3K/Akt Signal Pathway
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Q36245527Omentin-1 plasma levels and cholesterol metabolism in obese patients with diabetes mellitus type 1: impact of weight reduction.
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