A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.

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A new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1103971589
P356DOI10.1038/S41419-018-0635-5
P8608Fatcat IDrelease_likfcdamrbdbpjn6pa7gidvbhi
P932PMC publication ID5951921
P698PubMed publication ID29760380

P50authorTarik RegadQ55474203
Vincenzo DesiderioQ57063248
Francesca PainoQ57738649
Virginia TirinoQ61525395
Luigi MeleQ85886047
Davide LiccardoQ88263839
Marcella La NoceQ92173349
Gianpaolo PapaccioQ38317529
Michele CaragliaQ38321049
Antonio BarbieriQ39050494
David BoocockQ40891297
Paola StiusoQ42429610
P2093author name stringClaudio Arra
Angela Lombardi
Clare Coveney
Federica Papaccio
Gabriella Aquino
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Oxidative stress and ERK1/2 phosphorylation as predictors of outcome in hepatocellular carcinoma patients treated with sorafenib plus octreotide LAR.Q35064862
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Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cellsQ35238399
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Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.Q37577433
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A1 adenosine receptor-induced phosphorylation and modulation of transglutaminase 2 activity in H9c2 cells: A role in cell survival.Q38783979
Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapyQ38823095
A critical role of glucose-6-phosphate dehydrogenase in TAp73-mediated cell proliferationQ39056284
Reactive oxygen species-mediated endoplasmic reticulum stress and mitochondrial dysfunction contribute to polydatin-induced apoptosis in human nasopharyngeal carcinoma CNE cellsQ39495353
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Lipid-lowering effects of polydatin from Polygonum cuspidatum in hyperlipidemic hamstersQ46184773
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue5
P304page(s)572
P577publication date2018-05-14
P1433published inCell Death and DiseaseQ2197222
P1476titleA new inhibitor of glucose-6-phosphate dehydrogenase blocks pentose phosphate pathway and suppresses malignant proliferation and metastasis in vivo.
P478volume9

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cites work (P2860)
Q905561786-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 and 4: A pair of valves for fine-tuning of glucose metabolism in human cancer
Q94563331A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway
Q90045611Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition
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Q60301633Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2
Q91711345Exercise Training in Obese Rats Does Not Induce Browning at Thermoneutrality and Induces a Muscle-Like Signature in Brown Adipose Tissue
Q58763679Exploring immuno-regulatory mechanisms in the tumor microenvironment: Model and design of protocols for cancer remission
Q98384744Glucose 6-phosphate dehydrogenase inhibition sensitizes melanoma cells to metformin treatment
Q64119806Glucose-6-phosphate dehydrogenase blockade potentiates tyrosine kinase inhibitor effect on breast cancer cells through autophagy perturbation
Q90226833Hyperglycemia Associated Metabolic and Molecular Alterations in Cancer Risk, Progression, Treatment, and Mortality
Q89579652Metabolic classification of circulating tumor cells as a biomarker for metastasis and prognosis in breast cancer
Q97424076Metabolism of immune cells in cancer
Q100490619NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications
Q91794851Nanodrug with ROS and pH Dual-Sensitivity Ameliorates Liver Fibrosis via Multicellular Regulation
Q90288961RETRACTED ARTICLE: Chondro-protective effects of polydatin in osteoarthritis through its effect on restoring dysregulated autophagy via modulating MAPK, and PI3K/Akt signaling pathways
Q92092850TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism
Q89487254Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases
Q89550697The Pentose Phosphate Pathway and Its Involvement in Cisplatin Resistance
Q89996630The Redox Role of G6PD in Cell Growth, Cell Death, and Cancer
Q96641346The uninhibited pathway is not worth studying

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