Co-expression of β Subunits with the Voltage-Gated Sodium Channel NaV1.7: the Importance of Subunit Association and Phosphorylation and Their Effects on Channel Pharmacology and Biophysics.

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Co-expression of β Subunits with the Voltage-Gated Sodium Channel NaV1.7: the Importance of Subunit Association and Phosphorylation and Their Effects on Channel Pharmacology and Biophysics. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S12031-018-1082-6
P698PubMed publication ID29744740

P50authorMaxim V SokolovQ56754171
P2093author name stringBo Franzén
Olof Larsson
Petra Henrich-Noack
Michael Dabrowski
Carina Raynoschek
Martin Main
P2860cites workbeta 3: an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kineticsQ22253235
SCN9A mutations in paroxysmal extreme pain disorder: allelic variants underlie distinct channel defects and phenotypesQ28118877
Nav1.7 and other voltage-gated sodium channels as drug targets for pain reliefQ28273870
An SCN9A channelopathy causes congenital inability to experience painQ28278844
International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channelsQ28289125
Expression of auxiliary β subunits of sodium channels in primary afferent neurons and the effect of nerve injuryQ28567977
Identification of PN1, a predominant voltage-dependent sodium channel expressed principally in peripheral neuronsQ28569751
Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic ReleaseQ28601095
The importance of serine 161 in the sodium channel beta3 subunit for modulation of Na(V)1.2 gatingQ30430912
Gating properties of Na(v)1.7 and Na(v)1.8 peripheral nerve sodium channels.Q30730215
A novel Nav1.7 mutation producing carbamazepine-responsive erythromelalgiaQ33918510
Expression of the sodium channel beta3 subunit in injured human sensory neuronsQ34330876
Gain-of-function mutation in Nav1.7 in familial erythromelalgia induces bursting of sensory neuronsQ34426737
The roles of sodium channels in nociception: Implications for mechanisms of painQ34674268
The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicinQ35015930
Differential Expression of Sodium Channel β Subunits in Dorsal Root Ganglion Sensory NeuronsQ35922414
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neuronsQ36678533
Sodium channel auxiliary subunitsQ36857924
β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cellsQ37132478
Comparative study of the distribution of the alpha-subunits of voltage-gated sodium channels in normal and axotomized rat dorsal root ganglion neuronsQ39963179
Biophysical properties of human Na v1.7 splice variants and their regulation by protein kinase A.Q40003069
A stop codon mutation in SCN9A causes lack of pain sensationQ40114322
The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel functionQ40524605
Functional co-expression of the beta 1 and type IIA alpha subunits of sodium channels in a mammalian cell lineQ41368759
Inflammation-induced up-regulation of protein kinase Cgamma immunoreactivity in rat spinal cord correlates with enhanced nociceptive processing.Q41666416
Modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by protein kinase A and protein kinase C.Q41914888
A novel tetrodotoxin-sensitive, voltage-gated sodium channel expressed in rat and human dorsal root ganglia.Q42549337
Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populationsQ42618792
Beta3, a novel auxiliary subunit for the voltage gated sodium channel is upregulated in sensory neurones following streptozocin induced diabetic neuropathy in rat.Q43698686
Role of protein kinase Cϵ and protein kinase A in a model of paclitaxel-induced painful peripheral neuropathy in the ratQ43818810
Palmitylation, sulfation, and glycosylation of the alpha subunit of the sodium channel. Role of post-translational modifications in channel assembly.Q48195732
Biosynthesis and processing of the alpha subunit of the voltage-sensitive sodium channel in rat brain neuronsQ48319338
The sodium channel from rat brain. Separation and characterization of subunitsQ48453873
Differential modulation of sodium channel gating and persistent sodium currents by the beta1, beta2, and beta3 subunitsQ48645222
Sodium channel beta2 subunits regulate tetrodotoxin-sensitive sodium channels in small dorsal root ganglion neurons and modulate the response to pain.Q48678268
The saxitoxin receptor of the sodium channel from rat brain. Evidence for two nonidentical beta subunitsQ48860015
beta3, a novel auxiliary subunit for the voltage-gated sodium channel, is expressed preferentially in sensory neurons and is upregulated in the chronic constriction injury model of neuropathic painQ50721637
Transcriptional and functional profiles of voltage-gated Na+ channels in injured and non-injured DRG neurons in the SNI model of neuropathic painQ57990405
Upregulation of the Voltage-Gated Sodium Channel 2 Subunit in Neuropathic Pain Models: Characterization of Expression in Injured and Non-Injured Primary Sensory NeuronsQ57990434
P921main subjectphosphorylationQ242736
biophysicsQ7100
P577publication date2018-05-10
P1433published inJournal of Molecular NeuroscienceQ15708870
P1476titleCo-expression of β Subunits with the Voltage-Gated Sodium Channel NaV1.7: the Importance of Subunit Association and Phosphorylation and Their Effects on Channel Pharmacology and Biophysics.

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cites work (P2860)
Q64076290Antibodies and venom peptides: new modalities for ion channels
Q112997006SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol
Q64056713The Emerging Role of Voltage-Gated Sodium Channels in Tumor Biology
Q58617465[EXPRESS] Differential modulation of voltage-gated sodium channels by nerve growth factor in three major subsets of TrkA-expressing nociceptors

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