Human γδ T-Cell Control of Mucosal Immunity and Inflammation.

scientific article published on 7 May 2018

Human γδ T-Cell Control of Mucosal Immunity and Inflammation. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2018.00985
P932PMC publication ID5949325
P698PubMed publication ID29867962

P50authorMatthias EberlQ47346951
P2093author name stringNeil E McCarthy
P2860cites workBroad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICBQ22009950
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Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activationQ28250446
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Phosphoantigen/IL2 expansion and differentiation of Vγ2Vδ2 T cells increase resistance to tuberculosis in nonhuman primatesQ28535348
Infliximab induces clonal expansion of γδ-T cells in Crohn's disease: a predictor of lymphoma risk?Q28741471
Dynamic migration of γδ intraepithelial lymphocytes requires occludinQ30513960
A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infectionsQ33410795
Antigen-Presenting Human γδ T Cells Promote Intestinal CD4+ T Cell Expression of IL-22 and Mucosal Release of CalprotectinQ33567987
IL-17-producing γδ T cells switch migratory patterns between resting and activated statesQ33780948
Prolonged (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate-driven antimicrobial and cytotoxic responses of pulmonary and systemic Vgamma2Vdelta2 T cells in macaquesQ33832188
Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression ProfilesQ33865208
Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infectionQ33904052
Anti-Tumor Activity and Immunotherapeutic Potential of a Bisphosphonate ProdrugQ33920919
CD1-mediated gamma/delta T cell maturation of dendritic cellsQ33963163
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Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coliQ34104852
Exclusive antagonism of the α4 β7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primatesQ34261526
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BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammationQ34604279
Gammadelta intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surfaceQ35008436
Pooled sequencing of 531 genes in inflammatory bowel disease identifies an associated rare variant in BTNL2 and implicates other immune related genesQ35104679
Identification of a novel proinflammatory human skin-homing Vγ9Vδ2 T cell subset with a potential role in psoriasisQ35276090
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Azathioprine therapy selectively ablates human Vδ2⁺ T cells in Crohn's disease.Q36040498
Multieffector-functional immune responses of HMBPP-specific Vγ2Vδ2 T cells in nonhuman primates inoculated with Listeria monocytogenes ΔactA prfA*.Q36142246
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Interleukin 15 mediates epithelial changes in celiac diseaseQ56774967
Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper functionQ56880717
Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cellsQ59310681
Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel diseaseQ72462916
IL-15 is highly expressed in inflammatory bowel disease and regulates local T cell-dependent cytokine productionQ73567308
Flexible migration program regulates gamma delta T-cell involvement in humoral immunityQ73708692
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A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn's DiseaseQ46303978
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Early preferential stimulation of gamma delta T cells by TNF-alpha.Q48032586
γδ T Cells Coexpressing Gut Homing α4β7 and αE Integrins Define a Novel Subset Promoting Intestinal Inflammation.Q48175668
Synthesis and Biological Evaluation of (E)-4-Hydroxy-3-Methylbut-2-enyl Phosphate (HMBP) Aryloxy Triester Phosphoramidate Prodrugs as Activators of Vγ9/Vδ2 T-Cells Immune Response.Q49849833
Innately versatile: γδ17 T cells in inflammatory and autoimmune diseasesQ50084486
Distinctive features of tumor-infiltrating γδ T lymphocytes in human colorectal cancer.Q50550722
Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease.Q50793292
Reversal of allergic airway hyperreactivity after long-term allergen challenge depends on gammadelta T cells.Q51641636
Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models.Q52929775
MyD88-dependent signaling for IL-15 production plays an important role in maintenance of CD8 alpha alpha TCR alpha beta and TCR gamma delta intestinal intraepithelial lymphocytes.Q53624759
Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.Q36227215
Localization of gamma/delta T cells to the intestinal epithelium is independent of normal microbial colonizationQ36352037
Shared reactivity of V{delta}2(neg) {gamma}{delta} T cells against cytomegalovirus-infected cells and tumor intestinal epithelial cellsQ36403003
Human CD1-restricted T cell recognition of lipids from pollensQ36403172
Changes in human mucosal gamma delta T cell repertoire and function associated with the disease process in inflammatory bowel diseaseQ36437700
Nonpeptide antigens, presentation mechanisms, and immunological memory of human Vgamma2Vdelta2 T cells: discriminating friend from foe through the recognition of prenyl pyrophosphate antigensQ36732656
Presentation of peptide antigens by mouse CD1 requires endosomal localization and protein antigen processingQ36733819
The prognostic landscape of genes and infiltrating immune cells across human cancersQ36857285
Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells.Q37039445
TNF-alpha is a positive regulatory factor for human Vgamma2 Vdelta2 T cellsQ37120229
Origin, trafficking, and intraepithelial fate of gut-tropic T cells.Q37125790
Antigen-specific Vgamma2Vdelta2 T effector cells confer homeostatic protection against pneumonic plaque lesionsQ37183021
Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell CompartmentsQ37285138
Tissue-mediated control of immunopathology in coeliac diseaseQ37638199
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Epithelial decision makers: in search of the 'epimmunome'.Q37774241
Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunityQ37845442
Cancer Immunotherapy Using γδT Cells: Dealing with DiversityQ38283536
The burgeoning family of unconventional T cellsQ38611633
Prevention of Vγ9Vδ2 T Cell Activation by a Vγ9Vδ2 TCR Nanobody.Q38728528
Cutting edge: Generation of colitogenic Th17 CD4 T cells is enhanced by IL-17+ γδ T cells.Q38811539
Thymic Determinants of γδ T Cell DifferentiationQ38912597
Transcriptional Regulation of Tissue-Resident Lymphocytes.Q39034987
Proinflammatory Vδ2+ T cells populate the human intestinal mucosa and enhance IFN-γ production by colonic αβ T cellsQ39231527
Gut-homing Δ42PD1(+)Vδ2 T cells promote innate mucosal damage via TLR4 during acute HIV type 1 infection.Q40083110
An Ocular Commensal Protects against Corneal Infection by Driving an Interleukin-17 Response from Mucosal γδ T CellsQ40134258
Inhaled allergen-driven CD1c up-regulation and enhanced antigen uptake by activated human respiratory-tract dendritic cells in atopic asthma.Q40253442
Interleukin 15 controls the generation of the restricted T cell receptor repertoire of gamma delta intestinal intraepithelial lymphocytesQ41115758
Selective lysis of the autologous tumor by δTCS1+ γ/δ+ tumor-infiltrating lymphocytes from human lung carcinomasQ41713813
Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease.Q41941349
Peripheral blood monocytes are responsible for gammadelta T cell activation induced by zoledronic acid through accumulation of IPP/DMAPP.Q42183397
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.Q42259563
Effect of tumor necrosis factor-α blockade on mucosal addressin cell-adhesion molecule-1 in Crohn's diseaseQ42278326
Skin- and gut-homing molecules on human circulating γδ T cells and their dysregulation in inflammatory bowel disease.Q44117944
Mucosal T cells bearing TCRgammadelta play a protective role in intestinal inflammationQ44681379
Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gammadelta T cells: role of CD86 and inflammatory cytokinesQ45195924
Bacterial infections promote T cell recognition of self-glycolipidsQ45286619
Regulation of Immunity by ButyrophilinsQ45345594
The TCR-delta repertoire in human intestine undergoes characteristic changes during fetal to adult development.Q46004238
Distinct delta T cell receptor repertoires in monozygotic twins concordant for coeliac diseaseQ46110547
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmucosal immune systemQ6931261
cellQ7868
lymphocyte subsetsQ66004891
hemic and immune systemsQ70202933
P304page(s)985
P577publication date2018-05-07
P1433published inFrontiers in ImmunologyQ27723748
P1476titleHuman γδ T-Cell Control of Mucosal Immunity and Inflammation
P478volume9

Reverse relations

cites work (P2860)
Q58543705A power law function describes the time- and dose-dependency of Vγ9Vδ2 T cell activation by phosphoantigens
Q93109123Emerging role of γδ T cells in vaccine-mediated protection from infectious diseases
Q91840945Gubenzhike Recipe Ameliorates Respiratory Mucosal Immunity in Mice with Chronic Obstructive Pulmonary Disease through Upregulation of the γδT Lymphocytes and KGF Levels
Q91702845IL-7-dependent compositional changes within the γδ T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response
Q92882542The Control of Intestinal Inflammation: A Major Objective in the Research of Probiotic Strains as Alternatives to Antibiotic Growth Promoters in Poultry
Q93162748Translating gammadelta (γδ) T cells and their receptors into cancer cell therapies
Q58572524γδ T Cells in Antimalarial Immunity: New Insights Into Their Diverse Functions in Protection and Tolerance
Q90047092γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity