Ferroptosis-inducing agents compromise in vitro human islet viability and function.

scientific article

Ferroptosis-inducing agents compromise in vitro human islet viability and function. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41419-018-0506-0
P932PMC publication ID5964226
P698PubMed publication ID29789532

P50authorAndreas LinkermannQ30225182
Tatsuya KinQ63389800
Rena PawlickQ113622375
P2093author name stringStefan R Bornstein
A M James Shapiro
Gregory S Korbutt
Andrew R Pepper
Boris Gala-Lopez
Antonio Bruni
Karen Seeberger
Anissa F Gamble
P2860cites workIslet cell transplantation for the treatment of type 1 diabetes: recent advances and future challengesQ27010290
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimenQ28141785
SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysQ28385000
Five-year follow-up after clinical islet transplantationQ33218078
Ferroptosis: an iron-dependent form of nonapoptotic cell deathQ34032093
The role of iron and reactive oxygen species in cell deathQ34039363
Ferroptosis: Death by Lipid PeroxidationQ34045575
Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease modelsQ34408158
Synchronized renal tubular cell death involves ferroptosis.Q34447203
Programmed necrosis in inflammation: Toward identification of the effector moleculesQ34520528
Glutathione ethyl ester supplementation during pancreatic islet isolation improves viability and transplant outcomes in a murine marginal islet mass modelQ34592604
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetesQ35641724
Necroptosis and its role in inflammationQ38319916
Nonapoptotic cell death in acute kidney injury and transplantationQ38694095
Insulin secretion profiles are modified by overexpression of glutamate dehydrogenase in pancreatic islets.Q40605055
IL-1beta receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosisQ41326759
Oxygen radicals and signalingQ41750986
Glutamine induces heat-shock protein-70 and glutathione expression and attenuates ischemic damage in rat isletsQ42443383
A signaling role of glutamine in insulin secretionQ42455960
Beta-cell death and mass in syngeneically transplanted islets exposed to short- and long-term hyperglycemiaQ43833552
Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compoundQ44081017
Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivoQ44906014
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and DiseaseQ46292537
The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice.Q46690232
Intra-ductal glutamine administration reduces oxidative injury during human pancreatic islet isolation.Q46816085
Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice.Q50959885
Caspase inhibitor IDN6556 facilitates marginal mass islet engraftment in a porcine islet autotransplant model.Q51355426
Vulnerability of Islets in the Immediate Posttransplantation Period: Dynamic Changes in Structure and FunctionQ60192419
Oxidative stress increases potassium efflux from pancreatic islets by depletion of intracellular calcium storesQ73492249
Inhibition of glucose-induced insulin secretion by 4-hydroxy-2-nonenal and other lipid peroxidation productsQ74086355
Caspase inhibitor therapy enhances marginal mass islet graft survival and preserves long-term function in islet transplantationQ79782778
Response of human islets to isolation stress and the effect of antioxidant treatmentQ80787809
Risk factors for islet loss during culture prior to transplantationQ81482540
The caspase inhibitor IDN-6556 (PF3491390) improves marginal mass engraftment after islet transplantation in miceQ84149425
Ironing out cell death mechanismsQ84222393
Regulated cell death and inflammation: an auto-amplification loop causes organ failureQ85817618
Withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantationQ85896039
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P921main subjectferroptosisQ24466962
P304page(s)595
P577publication date2018-05-22
P1433published inCell Death and DiseaseQ2197222
P1476titleFerroptosis-inducing agents compromise in vitro human islet viability and function
P478volume9

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cites work (P2860)
Q96953404Bilirubin Protects Transplanted Islets by Targeting Ferroptosis
Q92000627Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
Q99204403Erastin-induced ferroptosis is a regulator for the growth and function of human pancreatic islet-like cell clusters
Q89518302Ferroptosis: past, present and future
Q90589751Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury
Q90047184Inhibitory Effect and Mechanism of Action of Quercetin and Quercetin Diels-Alder anti-Dimer on Erastin-Induced Ferroptosis in Bone Marrow-Derived Mesenchymal Stem Cells
Q93147646Liposomal delivery of ferritin heavy chain 1 (FTH1) siRNA in patient xenograft derived glioblastoma initiating cells suggests different sensitivities to radiation and distinct survival mechanisms
Q93047832Neuroprotective effect of deferoxamine on erastininduced ferroptosis in primary cortical neurons
Q89977091Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?
Q91907252The innate immune response to allotransplants: mechanisms and therapeutic potentials

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