Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections.

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Lectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections. is …
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scholarly articleQ13442814
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P356DOI10.1155/2018/3750646
P932PMC publication ID5964492
P698PubMed publication ID29854749

P50authorJoseph Calvin KouokamQ88942684
Milena MazalovskaQ124419141
P2860cites workRolling out HIV antiretroviral therapy in sub-Saharan Africa: 2003-2017.Q55397953
Squaric acid monoamide mannosides as ligands for the bacterial lectin FimH: covalent inhibition or not?Q64449044
Interaction of lectins with Neisseria gonorrhoeaeQ72609271
Urinary tract infections in HIV diseaseQ77965178
The Mycobacterium tuberculosis cell-surface glycoprotein apa as a potential adhesin to colonize target cells via the innate immune system pulmonary C-type lectin surfactant protein AQ79422100
Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisitionQ79687947
Cloning and characterization of a novel C-type lectin from Zhikong scallop Chlamys farreriQ79731939
[Virulence factors of uropathogens]Q84092417
Activity of and effect of subcutaneous treatment with the broad-spectrum antiviral lectin griffithsin in two laboratory rodent modelsQ24610025
Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family CoronaviridaeQ24648487
Scaleable manufacture of HIV-1 entry inhibitor griffithsin and validation of its safety and efficacy as a topical microbicide componentQ24650458
HIV/AIDS: trends in the Middle East and North Africa regionQ26767515
Role of N-linked glycans in the functions of hepatitis C virus envelope glycoproteinsQ27469844
Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and NeutralizationQ27481012
Mechanism by which the lectin actinohivin blocks HIV infection of target cellsQ27657228
Solution Structure of the Monovalent Lectin Microvirin in Complex with Man (1-2)Man Provides a Basis for Anti-HIV Activity with Low ToxicityQ27667444
Griffithsin, a potent HIV entry inhibitor, is an excellent candidate for anti-HIV microbicideQ28238899
Post-translational chemical modification(s) of proteinsQ28244774
HIV superinfectionQ28259889
Narcissus tazetta lectin shows strong inhibitory effects against respiratory syncytial virus, influenza A (H1N1, H3N2, H5N1) and B virusesQ28280442
Assignment of intrachain disulfide bonds and characterization of potential glycosylation sites of the type 1 recombinant human immunodeficiency virus envelope glycoprotein (gp120) expressed in Chinese hamster ovary cellsQ28288205
Proteins that bind high-mannose sugars of the HIV envelopeQ28295811
Pegylated interferon alfa-2b vs standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected patients: a randomized controlled trialQ28298301
Isolation and characterization of griffithsin, a novel HIV-inactivating protein, from the red alga Griffithsia spQ28299555
Pharmacokinetics of the Antiviral Lectin Griffithsin Administered by Different Routes Indicates Multiple Potential UsesQ28354743
Antiviral lectins from red and blue-green algae show potent in vitro and in vivo activity against hepatitis C virusQ28488338
Anti-Retroviral Lectins Have Modest Effects on Adherence of Trichomonas vaginalis to Epithelial Cells In Vitro and on Recovery of Tritrichomonas foetus in a Mouse Vaginal ModelQ28547132
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entryQ29620710
Eutirucallin: A Lectin with Antitumor and Antimicrobial Properties.Q40219408
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycansQ40261250
Plant lectins ConBr and CFL modulate expression toll-like receptors, pro-inflammatory cytokines and reduce the bacterial burden in macrophages infected with Salmonella enterica serovar TyphimuriumQ40335580
A beta-galactose-specific lectin isolated from the marine worm Chaetopterus variopedatus possesses anti-HIV-1 activityQ40346112
Middle East respiratory syndrome coronavirus infection is inhibited by griffithsinQ40610948
Lunatin, a novel lectin with antifungal and antiproliferative bioactivities from Phaseolus lunatus billbQ40680338
Interactions among HIV gp120, CD4, and CXCR4: dependence on CD4 expression level, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies.Q41012335
Making the case for multipurpose prevention technologies: the socio-epidemiological rationaleQ41692634
Carbohydrate structures of the human-immunodeficiency-virus (HIV) recombinant envelope glycoprotein gp120 produced in Chinese-hamster ovary cellsQ42163960
Multiple and atypical opportunistic infections in a HIV patient with Toxoplasma myocarditisQ42203923
Molecular cloning of actinohivin, a novel anti-HIV protein from an actinomycete, and its expression in Escherichia coliQ42644711
Cloning and expression of a novel cDNA encoding a mannose-specific jacalin-related lectin from Oryza sativaQ42675880
Concanavalin A enhances phagocytosis and killing of Candida albicans by mice peritoneal neutrophils and macrophagesQ44058224
Characterization, molecular cloning, and in silico analysis of a novel mannose-binding lectin from Polygonatum odoratum (Mill.) with anti-HSV-II and apoptosis-inducing activitiesQ44515841
Jackfruit lectin: properties of mitogenicity and the inhibition of herpesvirus infectionQ44568423
Incidence and predictors of severe liver fibrosis in human immunodeficiency virus-infected patients with chronic hepatitis C: a European collaborative studyQ44696144
The impact of incident and prevalent herpes simplex virus-2 infection on the incidence of HIV-1 infection among commercial sex workers in South AfricaQ45442173
Vitamin A supplementation and genital shedding of herpes simplex virus among HIV-1-infected women: a randomized clinical trialQ45654235
Association between cervical shedding of herpes simplex virus and HIV-1.Q45729964
Herpes simplex virus infection induces replication of human immunodeficiency virus type 1.Q45739372
PgTeL, the lectin found in Punica granatum juice, is an antifungal agent against Candida albicans and Candida krusei.Q46244343
Sexually transmitted infections in the era of antiretroviral-based HIV prevention: Priorities for discovery research, implementation science, and community involvementQ47556049
Access to influenza immunisation services by HIV positive patients in the UK.Q47688925
Antimicrobial lectin from Schinus terebinthifolius leaf.Q50020900
Aging of hepatitis C virus (HCV)-infected persons in the United States: a multiple cohort model of HCV prevalence and disease progressionQ39935106
A novel mannose-binding tuber lectin from Typhonium divaricatum (L.) Decne (family Araceae) with antiviral activity against HSV-II and anti-proliferative effect on human cancer cell linesQ40121220
Entry Inhibition of Influenza Viruses with High Mannose Binding Lectin ESA-2 from the Red Alga Eucheuma serra through the Recognition of Viral HemagglutininQ30375215
High mannose-specific lectin (KAA-2) from the red alga Kappaphycus alvarezii potently inhibits influenza virus infection in a strain-independent mannerQ30398417
High mannose-binding lectin with preference for the cluster of alpha1-2-mannose from the green alga Boodlea coacta is a potent entry inhibitor of HIV-1 and influenza virusesQ30401412
Human mannose-binding protein inhibits infection of HeLa cells by Chlamydia trachomatis.Q33752459
Intracellular lectins associated with N-linked glycoprotein trafficQ33783720
Multiple antiviral activities of cyanovirin-N: blocking of human immunodeficiency virus type 1 gp120 interaction with CD4 and coreceptor and inhibition of diverse enveloped virusesQ33804363
Candida infections of the genitourinary tractQ33825621
The glycointeractome of serogroup B Neisseria meningitidis strain MC58.Q33915909
Fruit-specific lectins from banana and plantain.Q33921297
Herpes simplex virus infectionsQ33948597
Cyanovirin-N, a potent human immunodeficiency virus-inactivating protein, blocks both CD4-dependent and CD4-independent binding of soluble gp120 (sgp120) to target cells, inhibits sCD4-induced binding of sgp120 to cell-associated CXCR4, and dissociaQ33981547
Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycleQ34003514
Entry of hepatitis C virus and human immunodeficiency virus is selectively inhibited by carbohydrate-binding agents but not by polyanionsQ34004118
Microvirin, a novel alpha(1,2)-mannose-specific lectin isolated from Microcystis aeruginosa, has anti-HIV-1 activity comparable with that of cyanovirin-N but a much higher safety profileQ34042738
The N-glycans of Trichomonas vaginalis contain variable core and antennal modifications.Q34044337
Wheat germ agglutinin blockage of chlamydial attachment sites: antagonism by N-acetyl-D-glucosamineQ34092151
Congenital toxoplasmosis: a reviewQ34239119
Crystal structure of banana lectin reveals a novel second sugar binding siteQ34424978
Virulence factors of uropathogensQ34468484
Reviews of anti-infective agents: maraviroc: the first of a new class of antiretroviral agentsQ34592841
HIV entry inhibitors.Q34654433
Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activationQ34682171
Interactions of HIV, other sexually transmitted diseases, and genital tract inflammation facilitating local pathogen transmission and acquisitionQ34799419
Inhibition of severe acute respiratory syndrome coronavirus replication in a lethal SARS-CoV BALB/c mouse model by stinging nettle lectin, Urtica dioica agglutininQ34894092
Global estimates of prevalent and incident herpes simplex virus type 2 infections in 2012.Q34995329
Inhibition of hepatitis C virus 3a genotype entry through Glanthus Nivalis AgglutininQ35053124
Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide developmentQ35137168
Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41.Q35137657
Griffithsin has antiviral activity against hepatitis C virusQ35363633
The entry of entry inhibitors: a fusion of science and medicineQ35976966
Metaanalysis and metaregression in interpreting study variability in the impact of sexually transmitted diseases on susceptibility to HIV infectionQ36136613
Cyanovirin-N inhibits mannose-dependent Mycobacterium-C-type lectin interactions but does not protect against murine tuberculosisQ36252443
Engineering a therapeutic lectin by uncoupling mitogenicity from antiviral activityQ36271352
Griffithsin and Carrageenan Combination To Target Herpes Simplex Virus 2 and Human PapillomavirusQ36290533
Interaction with lectins and differential wheat germ agglutinin binding of pyocin 103-sensitive and -resistant Neisseria gonorrhoeaeQ36309029
Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies.Q36331074
Epidemiology of viral hepatitis and HIV co-infectionQ36341016
Inhibition of HIV entry by carbohydrate-binding proteinsQ36434175
Potential antivirals and antiviral strategies against SARS coronavirus infectionsQ36441511
Candida mannan: chemistry, suppression of cell-mediated immunity, and possible mechanisms of actionQ36636840
Microbicide drug candidates to prevent HIV infectionQ36750849
Adhesins in human fungal pathogens: glue with plenty of stick.Q36757905
Griffithsin protects mice from genital herpes by preventing cell-to-cell spreadQ36827173
Respiratory infection complicating HIV infectionQ37085842
Antifungal activity of lectins against yeast of vaginal secretionQ37159860
A sugar binding protein cyanovirin-N blocks herpes simplex virus type-1 entry and cell fusionQ37336219
Inhibition of hepatitis C virus by the cyanobacterial protein Microcystis viridis lectin: mechanistic differences between the high-mannose specific lectins MVL, CV-N, and GNA.Q37533386
Differential inhibitory effects of cyanovirin-N, griffithsin, and scytovirin on entry mediated by envelopes of gammaretroviruses and deltaretrovirusesQ37547033
Biofilm formation on dental restorative and implant materialsQ37744299
Pre-exposure prophylaxis for HIV infection and new sexually transmitted infections among men who have sex with men.Q37836118
Interactions between HIV infection and other sexually transmitted diseasesQ37875787
Binding of Galanthus nivalis lectin to Chlamydia trachomatis and inhibition of in vitro infection.Q37886378
The characterization of lectin-binding proteins of Chlamydia trachomatis as glycoproteinsQ37894924
Candida and candidiasis in HIV-infected patients: where commensalism, opportunistic behavior and frank pathogenicity lose their bordersQ37999620
Cyanovirin-N defines a new class of antiviral agent targeting N-linked, high-mannose glycans in an oligosaccharide-specific mannerQ38301855
Essential regions for antiviral activities of actinohivin, a sugar-binding anti-human immunodeficiency virus protein from an actinomyceteQ38327540
Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelopeQ38343814
Molecular dynamics simulations of T-2410 and T-2429 HIV fusion inhibitors interacting with model membranes: Insight into peptide behavior, structure and dynamicsQ38677376
CasuL: A new lectin isolated from Calliandra surinamensis leaf pinnulae with cytotoxicity to cancer cells, antimicrobial activity and antibiofilm effect.Q38717445
HIV Treatment and Prevention: An Overview of Recommendations From the IAS-USA Antiretroviral Guidelines PanelQ38731295
Griffithsin binds to the glycosylated proteins (E and prM) of Japanese encephalitis virus and inhibit its infectionQ38798866
Men's attitudes to condoms and female controlled means of protection against HIV and STDs in south-western Uganda.Q38883926
Antiviral and antitumor activities of the lectin extracted from Aspidistra elatiorQ38889589
Antiviral lectins: Selective inhibitors of viral entryQ38891044
Actinohivin, a novel anti-HIV protein from an actinomycete that inhibits syncytium formation: isolation, characterization, and biological activitiesQ38943968
Griffithsin inhibits Japanese encephalitis virus infection in vitro and in vivoQ39262442
Legume lectins inhibit human parainfluenza virus type 2 infection by interfering with the entryQ39304310
Identification of a critical motif for the human immunodeficiency virus type 1 (HIV-1) gp41 core structure: implications for designing novel anti-HIV fusion inhibitorsQ39766027
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectinfectionQ166231
lectinQ408693
prevention of HIV/AIDSQ7242372
human immunodeficiency virus infectious diseaseQ18556697
RNA virus infectious diseaseQ18967413
Retroviridae infectious diseaseQ19000689
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)3750646
P577publication date2018-05-08
P1433published inBioMed Research InternationalQ17509958
P1476titleLectins as Promising Therapeutics for the Prevention and Treatment of HIV and Other Potential Coinfections
P478volume2018