| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Linda R. Watkins | Q4291013 |
| Mark R. Hutchinson | Q42967461 | ||
| P2093 | author name string | Kenner C Rice | |
| Steven F Maier | |||
| Kirk W Johnson | |||
| Sondra T Bland | |||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | nervous system | Q9404 |
| cell | Q7868 | ||
| opioid | Q427523 | ||
| P304 | page(s) | 98-111 | |
| P577 | publication date | 2007-11-02 | |
| P1433 | published in | The Scientific World Journal | Q7762585 |
| P1476 | title | Opioid-induced glial activation: mechanisms of activation and implications for opioid analgesia, dependence, and reward. | |
| P478 | volume | 7 |
| Q36464466 | "Listening" and "talking" to neurons: implications of immune activation for pain control and increasing the efficacy of opioids |
| Q36431202 | A combinational effect of acetaminophen and oriental herbs on the regulation of inflammatory mediators in microglia cell line, BV2 |
| Q48472695 | Acute Morphine Exposure Increases the Brain Distribution of [18F]DPA-714, a PET Biomarker of Glial Activation in Nonhuman Primates. |
| Q33709318 | Acute morphine alters GABAergic transmission in the central amygdala during naloxone-precipitated morphine withdrawal: role of cyclic AMP. |
| Q24634101 | An IL-1 receptor antagonist blocks a morphine-induced attenuation of locomotor recovery after spinal cord injury |
| Q55646588 | An emerging new paradigm in opioid withdrawal: a critical role for glia-neuron signaling in the periaqueductal gray. |
| Q64921565 | Analgesic efficacy of laser acupuncture and electroacupuncture in cats undergoing ovariohysterectomy. |
| Q43105759 | Analgesic tolerance to morphine is regulated by PPARγ. |
| Q37208498 | Blockade of Toll-like receptor 4 attenuates morphine tolerance and facilitates the pain relieving properties of morphine |
| Q36394429 | Buprenorphine-mediated transition from opioid agonist to antagonist treatment: state of the art and new perspectives |
| Q28485070 | Ceasing intrathecal therapy in chronic non-cancer pain: an invitation to shift from biomedical focus to active management |
| Q38700966 | Chronic Daily Headache: Mechanisms and Principles of Management |
| Q34980268 | Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6. |
| Q34658014 | Codeine-induced hyperalgesia and allodynia: investigating the role of glial activation |
| Q37790054 | Combination drug therapy for chronic pain: a call for more clinical studies |
| Q41496441 | Complement factor C5a and C5a receptor contribute to morphine tolerance and withdrawal-induced hyperalgesia in rats |
| Q45054320 | Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation |
| Q37351994 | Cytokine and chemokine regulation of sensory neuron function. |
| Q39904129 | Design, synthesis, and evaluation of biotinylated opioid derivatives as novel probes to study opioid pharmacology |
| Q46033333 | Diagnosis, characterization, and 3-month outcome after detoxification of 39 patients with narcotic bowel syndrome. |
| Q37638416 | Differential effects of opioid-related ligands and NSAIDs in nonhuman primate models of acute and inflammatory pain |
| Q36172356 | Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats |
| Q35327472 | Dose escalation during the first year of long-term opioid therapy for chronic pain |
| Q35676825 | Early-life experience decreases drug-induced reinstatement of morphine CPP in adulthood via microglial-specific epigenetic programming of anti-inflammatory IL-10 expression |
| Q39042240 | Ecosystem response to nutrient enrichment across an urban airshed in the Sonoran Desert |
| Q38844785 | Effects of Ibudilast on the Subjective, Reinforcing, and Analgesic Effects of Oxycodone in Recently Detoxified Adults with Opioid Dependence |
| Q41910683 | Effects of Opioids on Esophageal Dysfunction |
| Q34478755 | Essential role of toll-like receptor 2 in morphine-induced microglia activation in mice |
| Q37227174 | Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury |
| Q37438107 | Evidence for a role of heat shock protein-90 in toll like receptor 4 mediated pain enhancement in rats |
| Q28254885 | Evidence that opioids may have toll-like receptor 4 and MD-2 effects |
| Q24612607 | Evidence that tricyclic small molecules may possess toll-like receptor and myeloid differentiation protein 2 activity |
| Q35122783 | Exploring the neuroimmunopharmacology of opioids: an integrative review of mechanisms of central immune signaling and their implications for opioid analgesia |
| Q48333171 | Gabapentin Completely Attenuated the Acute Morphine-Induced c-Fos Expression in the Rat Nucleus Accumbens |
| Q33872764 | Gabapentin improves cold-pressor pain responses in methadone-maintained patients |
| Q37189198 | Glia in pathological pain: a role for fractalkine |
| Q43076075 | Glial and neuroinflammatory targets for treating substance use disorders |
| Q27003932 | Glial modulators: a novel pharmacological approach to altering the behavioral effects of abused substances |
| Q28112161 | Glutamatergic transmission in drug reward: implications for drug addiction |
| Q34789109 | Hysterectomy and predictors for opioid prescription in a chronic pain clinic sample |
| Q37175799 | Ibudilast in healthy volunteers: safety, tolerability and pharmacokinetics with single and multiple doses |
| Q52595639 | Identification of lncRNA expression profiles and ceRNA analysis in the spinal cord of morphine-tolerant rats. |
| Q38853365 | Immunoadolescence: Neuroimmune development and adolescent behavior |
| Q92587229 | Impact of sex on pain and opioid analgesia: a review |
| Q47103150 | Increased Hyperalgesia and Proinflammatory Cytokines in the Spinal Cord and Dorsal Root Ganglion After Surgery and/or Fentanyl Administration in Rats |
| Q34399714 | Increased responsiveness of peripheral blood mononuclear cells to in vitro TLR 2, 4 and 7 ligand stimulation in chronic pain patients |
| Q34199534 | Inflammation and inflammatory control in interstitial cystitis/bladder pain syndrome: Associations with painful symptoms. |
| Q92485986 | Inflammatory mediators of opioid tolerance: Implications for dependency and addiction |
| Q41895164 | Intrathecal morphine attenuates recovery of function after a spinal cord injury |
| Q38097975 | Ketamine and peripheral inflammation. |
| Q55305665 | Linking opioid-induced hyperalgesia and withdrawal-associated injury site pain: a case report. |
| Q92479088 | Low-dose naltrexone as a treatment for chronic fatigue syndrome |
| Q93142663 | Lumbar foraminal neuropathy: an update on non-surgical management |
| Q26853370 | Medications development for opioid abuse |
| Q26828742 | Metaplasticity and behavior: how training and inflammation affect plastic potential within the spinal cord and recovery after injury |
| Q37438487 | Minocycline suppresses morphine-induced respiratory depression, suppresses morphine-induced reward, and enhances systemic morphine-induced analgesia |
| Q35660841 | Molecular and contextual markers of hepatitis C virus and drug abuse. |
| Q93000944 | Morphine Exacerbates Postfracture Nociceptive Sensitization, Functional Impairment, and Microglial Activation in Mice |
| Q40037212 | Morphine Inhibited the Rat Neural Stem Cell Proliferation Rate by Increasing Neuro Steroid Genesis. |
| Q35924760 | Morphine activates neuroinflammation in a manner parallel to endotoxin |
| Q37021812 | Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation |
| Q48629661 | Morphine preconditioning protects against LPS-induced neuroinflammation and memory deficit |
| Q36807732 | Morphine-enhanced apoptosis in selective brain regions of neonatal rats |
| Q35833987 | Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase |
| Q35124986 | Naloxone-precipitated morphine withdrawal behavior and brain IL-1β expression: comparison of different mouse strains |
| Q36244856 | Naltrexone treatment reverses astrocyte atrophy and immune dysfunction in self-harming macaques. |
| Q38245693 | Narcotic bowel syndrome and opioid-induced constipation |
| Q33834882 | Neonatal Escherichia coli infection alters glial, cytokine, and neuronal gene expression in response to acute amphetamine in adolescent rats |
| Q89422884 | Neuronal and glial factors contributing to sex differences in opioid modulation of pain |
| Q34057763 | New directions in migraine |
| Q38080664 | New perspectives in the diagnosis and management of enteric neuropathies. |
| Q28288846 | Non-stereoselective reversal of neuropathic pain by naloxone and naltrexone: involvement of toll-like receptor 4 (TLR4) |
| Q38090368 | Opioid administration following spinal cord injury: implications for pain and locomotor recovery |
| Q35866257 | Opioid treatment of experimental pain activates nuclear factor-κB. |
| Q27021477 | Opioid-induced central immune signaling: implications for opioid analgesia |
| Q38998329 | Opioids and Chronic Pain: Where Is the Balance? |
| Q34112578 | Pain and opioid addiction: what is the connection? |
| Q24646738 | Pathological and protective roles of glia in chronic pain |
| Q33925677 | Pathological pain and the neuroimmune interface |
| Q41164232 | Pharmacological characterization of LPS and opioid interactions at the toll-like receptor 4. |
| Q57596842 | Pioglitazone prevents morphine antinociception tolerance and withdrawal symptoms in rats |
| Q28274052 | Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences |
| Q36377051 | Prior exposure to repeated morphine potentiates mechanical allodynia induced by peripheral inflammation and neuropathy |
| Q24650758 | Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia |
| Q36064141 | Pronociceptive and Antinociceptive Effects of Buprenorphine in the Spinal Cord Dorsal Horn Cover a Dose Range of Four Orders of Magnitude |
| Q35738103 | Reduction of alcohol drinking of alcohol-preferring (P) and high-alcohol drinking (HAD1) rats by targeting phosphodiesterase-4 (PDE4). |
| Q37143300 | Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast) |
| Q88213582 | Repeated Morphine Prolongs Postoperative Pain in Male Rats |
| Q35818737 | Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist |
| Q38013662 | Role of astrocytes in pain |
| Q39194963 | Role of phosphodiesterase inhibitor Ibudilast in morphine-induced hippocampal injury |
| Q38951157 | Sex Differences in Microglia Activity within the Periaqueductal Gray of the Rat: A Potential Mechanism Driving the Dimorphic Effects of Morphine. |
| Q37432134 | Sex differences in innate immunity and its impact on opioid pharmacology. |
| Q35685251 | Sex differences in motivational responses to dietary fat in Syrian hamsters |
| Q47377731 | Sex-dependent influences of morphine and its metabolites on pain sensitivity in the rat. |
| Q38574243 | Spatial and temporal trends of ozone distribution in the Jizerské hory Mountains of the Czech Republic. |
| Q39105980 | Sterile Neuroinflammation and Strategies for Therapeutic Intervention |
| Q37831649 | Stress- and glucocorticoid-induced priming of neuroinflammatory responses: potential mechanisms of stress-induced vulnerability to drugs of abuse |
| Q35087100 | Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities |
| Q36253520 | Structure-Activity Relationships of (+)-Naltrexone-Inspired Toll-like Receptor 4 (TLR4) Antagonists |
| Q38542687 | Targeting Opioid-Induced Hyperalgesia in Clinical Treatment: Neurobiological Considerations |
| Q26992220 | Targeting Toll-like receptors with small molecule agents |
| Q49496393 | Targeting cytokines for morphine tolerance: a narrative review. |
| Q46051242 | Targeting novel mechanisms of pain in sickle cell disease |
| Q89584319 | Targeting novel mechanisms of pain in sickle cell disease |
| Q24650739 | The "toll" of opioid-induced glial activation: improving the clinical efficacy of opioids by targeting glia |
| Q38600704 | The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain. |
| Q41019070 | The Opioid Challenge |
| Q42182469 | The Role of TNFα in the Periaqueductal Gray During Naloxone-Precipitated Morphine Withdrawal in Rats |
| Q37648767 | The effect of gut microbiome on tolerance to morphine mediated antinociception in mice |
| Q33727021 | The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users |
| Q41902714 | The glial activation inhibitor AV411 reduces morphine-induced nucleus accumbens dopamine release |
| Q33886313 | The glial cell modulator and phosphodiesterase inhibitor, AV411 (ibudilast), attenuates prime- and stress-induced methamphetamine relapse |
| Q41454933 | The protective effect of hydromorphone to ischemia in rat glial cells |
| Q37485007 | The therapeutic potential of interleukin-10 in neuroimmune diseases. |
| Q35681383 | Therapeutic Developments Targeting Toll-like Receptor-4-Mediated Neuroinflammation |
| Q48601983 | Toll-like Receptor 4 Mediates Morphine-Induced Neuroinflammation and Tolerance via Soluble Tumor Necrosis Factor Signaling |
| Q34018705 | Toll-like receptor 4 in CNS pathologies |
| Q35217760 | Toll-like receptor 4 is a regulator of monocyte and electroencephalographic responses to sleep loss |
| Q33604982 | Toll-like receptor 4 mutant and null mice retain morphine-induced tolerance, hyperalgesia, and physical dependence |
| Q41457843 | Toll-like receptor 4-mediated nuclear factor-κB activation in spinal cord contributes to chronic morphine-induced analgesic tolerance and hyperalgesia in rats |
| Q35779664 | Toll-like receptor expression and activation in astroglia: differential regulation by HIV-1 Tat, gp120, and morphine. |
| Q35830682 | Toll-like receptors in chronic pain |
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| Q40277139 | Ultra-low dose naltrexone attenuates chronic morphine-induced gliosis in rats |
| Q33987944 | Validation of a preclinical spinal safety model: effects of intrathecal morphine in the neonatal rat |
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| Q37420079 | Withdrawal-associated injury site pain (WISP): a descriptive case series of an opioid cessation phenomenon |
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