| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2018PNAS..115.3249N |
| P356 | DOI | 10.1073/PNAS.1719190115 |
| P932 | PMC publication ID | 5879690 |
| P698 | PubMed publication ID | 29531094 |
| P50 | author | John T. Groves | Q6259993 |
| J T Hunt | Q67487747 | ||
| Aaron Balog | Q73305437 | ||
| Patrick A Kates | Q125271538 | ||
| P2093 | author name string | Steven P Seitz | |
| Zeyu Lin | |||
| Xiao Zhu | |||
| Chunhong Yan | |||
| Micah T Nelp | |||
| Alban Allentoff | |||
| Robert Borzilleri | |||
| John A Newitt | |||
| Lynn Abell | |||
| Hal A Lewis | |||
| Derrick Maley | |||
| P2860 | cites work | Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes. | Q50978363 |
| Indoleamine 2,3-dioxygenase. Equilibrium studies of the tryptophan binding to the ferric, ferrous, and CO-bound enzymes | Q71133159 | ||
| Comparison of the sequences of Turboand Sulculus indoleamine dioxygenase-like myoglobin genes | Q73308801 | ||
| Decreased protein nitration in macrophages that overexpress indoleamine 2, 3-dioxygenase | Q79356267 | ||
| Interactions between nitric oxide and indoleamine 2,3-dioxygenase | Q79882314 | ||
| Cytochrome b(5) is a major reductant in vivo of human indoleamine 2,3-dioxygenase expressed in yeast | Q83015185 | ||
| Identification and optimization of a novel series of indoleamine 2,3-dioxygenase inhibitors | Q89180445 | ||
| Challenges in the Discovery of Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors | Q38477478 | ||
| Analysis of Reaction Intermediates in Tryptophan 2,3-Dioxygenase: A Comparison with Indoleamine 2,3-Dioxygenase | Q39108329 | ||
| Inhibitory substrate binding site of human indoleamine 2,3-dioxygenase | Q39948793 | ||
| Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite | Q40354381 | ||
| The mechanism of substrate inhibition in human indoleamine 2,3-dioxygenase | Q41173924 | ||
| Effects of dissolved oxygen levels and the role of extra- and intracellular amino acid concentrations upon the metabolism of mammalian cell lines during batch and continuous cultures | Q41763119 | ||
| Human indolylamine 2,3-dioxygenase. Its tissue distribution, and characterization of the placental enzyme | Q42129941 | ||
| Antioxidants inhibit indoleamine 2,3-dioxygenase in IFN-gamma-activated human macrophages: posttranslational regulation by pyrrolidine dithiocarbamate | Q43600956 | ||
| Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase | Q44135171 | ||
| Structural insights into substrate and inhibitor binding sites in human indoleamine 2,3-dioxygenase 1. | Q46220873 | ||
| Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate | Q46558798 | ||
| Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins | Q47245449 | ||
| Discovery of IDO1 Inhibitors: From Bench to Bedside | Q47547812 | ||
| In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis | Q48098105 | ||
| The Nature and Reactivity of Ferryl Heme in Compounds I and II. | Q48254444 | ||
| Development of a series of novel o-phenylenediamine-based indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. | Q49340628 | ||
| Prevention of allogeneic fetal rejection by tryptophan catabolism | Q24336018 | ||
| Kynurenine is an endothelium-derived relaxing factor produced during inflammation | Q24630488 | ||
| Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase | Q27661554 | ||
| His64(E7)-->Tyr apomyoglobin as a reagent for measuring rates of hemin dissociation | Q27731565 | ||
| Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase | Q28115622 | ||
| Inhibition of T cell proliferation by macrophage tryptophan catabolism | Q28142922 | ||
| Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase | Q28204166 | ||
| Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase | Q28572418 | ||
| The association rate constant for heme binding to globin is independent of protein structure. | Q30424977 | ||
| Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications. | Q33742950 | ||
| Restriction of Toxoplasma gondii growth in human brain microvascular endothelial cells by activation of indoleamine 2,3-dioxygenase | Q34009484 | ||
| The mechanism of formation of N-formylkynurenine by heme dioxygenases. | Q34213607 | ||
| Indoleamine 2,3 dioxygenase and metabolic control of immune responses | Q34308495 | ||
| IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan | Q34319398 | ||
| Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy. | Q34394487 | ||
| IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation | Q34396547 | ||
| Substrate Oxidation by Indoleamine 2,3-Dioxygenase: EVIDENCE FOR A COMMON REACTION MECHANISM | Q34499772 | ||
| O-alkylhydroxylamines as rationally-designed mechanism-based inhibitors of indoleamine 2,3-dioxygenase-1. | Q34506977 | ||
| IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance | Q34512092 | ||
| Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease | Q34555620 | ||
| Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase. | Q34657500 | ||
| Evidence for a ferryl intermediate in a heme-based dioxygenase. | Q35006504 | ||
| Tryptophan-degrading enzymes in tumoral immune resistance | Q35042385 | ||
| Oxidation and loss of heme in soluble guanylyl cyclase from Manduca sexta | Q35083181 | ||
| Heme-thiolate ferryl of aromatic peroxygenase is basic and reactive | Q35229431 | ||
| The role of indoleamine 2,3-dioxygenase in the induction of immune tolerance: focus on hematology | Q37331219 | ||
| Relationship between interferon-gamma, indoleamine 2,3-dioxygenase, and tryptophan catabolism | Q37349845 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 13 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 6 | |
| P304 | page(s) | 3249-3254 | |
| P577 | publication date | 2018-03-12 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Immune-modulating enzyme indoleamine 2,3-dioxygenase is effectively inhibited by targeting its apo-form | |
| P478 | volume | 115 |
| Q90811886 | Actualités et perspectives concernant l’immunothérapie en oncologie thoracique |
| Q90632243 | Design, Synthesis and Biological Evaluation of Phenyl Urea Derivatives as IDO1 Inhibitors |
| Q91642873 | Discovery and Characterisation of Dual Inhibitors of Tryptophan 2,3-Dioxygenase (TDO2) and Indoleamine 2,3-Dioxygenase 1 (IDO1) Using Virtual Screening |
| Q89768633 | Discovery of Hydroxyamidine Based Inhibitors of IDO1 for Cancer Immunotherapy with Reduced Potential for Glucuronidation |
| Q89977752 | From Synthesis to Utilization: The Ins and Outs of Mitochondrial Heme |
| Q90132119 | Heme binding to human CLOCK affects interactions with the E-box |
| Q58618625 | High-resolution structures of inhibitor complexes of human indoleamine 2,3-dioxygenase 1 in a new crystal form |
| Q92688382 | Inhibitory effects of flavonoids isolated from Sophora flavescens on indoleamine 2,3-dioxygenase 1 activity |
| Q57791960 | Mapping the Binding Trajectory of a Suicide Inhibitor in Human Indoleamine 2,3-Dioxygenase 1 |
| Q58789294 | Myeloid-Derived Suppressor Cells as a Regulator of Immunity in Organ Transplantation |
| Q90453533 | New Insights from Crystallographic Data: Diversity of Structural Motifs and Molecular Recognition Properties between Groups of IDO1 Structures |
| Q89555118 | Positive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation |
| Q64928020 | Role of IDO and TDO in Cancers and Related Diseases and the Therapeutic Implications. |
| Q56335204 | Targeted Isolation of Tsitsikammamines from the Antarctic Deep-Sea Sponge Latrunculia biformis by Molecular Networking and Anticancer Activity |
| Q59830619 | Targeting Metalloenzymes for Therapeutic Intervention |
| Q98164380 | The relationship between blood metabolites of the tryptophan pathway and kidney function: a bidirectional Mendelian randomization analysis |
| Q91277335 | Tracking Hidden Binding Pockets Along the Molecular Recognition Path of l-Trp to Indoleamine 2,3-Dioxygenase 1 |
| Q91559758 | Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond |
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