Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis.

scientific article

Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2018.00983
P932PMC publication ID5945820
P698PubMed publication ID29780394

P50authorMarina SaresellaQ56816795
Federica PianconeQ57206990
Ivana MarventanoQ79637658
Marco RovarisQ83810349
P2093author name stringMario Clerici
Laura Mendozzi
Domenico Caputo
Francesca La Rosa
Maria Antonia Santangelo
P2860cites workAdvances in T Helper 17 Cell Biology: Pathogenic Role and Potential Therapy in Multiple SclerosisQ26771957
Interleukin 18 (IL-18) as a target for immune interventionQ28068555
Gout-associated uric acid crystals activate the NALP3 inflammasomeQ28131797
Serum uric acid and multiple sclerosisQ28275324
Cryopyrin activates the inflammasome in response to toxins and ATPQ28291313
The NALP3 inflammasome is involved in the innate immune response to amyloid-betaQ29615595
Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis.Q34059225
Uric acid in relapsing-remitting multiple sclerosis: a 2-year longitudinal studyQ34462274
Serum uric acid levels of patients with multiple sclerosis and other neurological diseasesQ34583852
Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patientsQ34606170
Inflammasomes and autoimmunityQ34670542
Heterogeneity versus homogeneity of multiple sclerosisQ34893931
Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary studyQ35454481
Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome SignalingQ35953090
Increased interleukin 12 production in progressive multiple sclerosis: induction by activated CD4+ T cells via CD40 ligandQ35957193
Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasomeQ36431053
NLRP3 Inflammasome and MS/EAE.Q36566053
NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responsesQ36670359
Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itselfQ36976299
Interleukin-18 and IL-18 binding proteinQ37220336
A Fluorescent Reporter Mouse for Inflammasome Assembly Demonstrates an Important Role for Cell-Bound and Free ASC Specks during In Vivo Infection.Q37741862
T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitisQ37744165
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Serum uric acid levels in patients with multiple sclerosis: a meta-analysisQ37983970
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Serum metabolic profile in multiple sclerosis patientsQ38756394
Soluble Uric Acid Activates the NLRP3 Inflammasome.Q38770923
Serum levels of interleukin (IL)-18, IL-23 and IL-17 in Chinese patients with multiple sclerosisQ39666226
Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis.Q40477272
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammationQ40891679
T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosisQ43457921
Augmented type 1 cytokines and human endogenous retroviruses specific immune responses in patients with acute multiple sclerosisQ44418280
Uric acid is a danger signal activating NALP3 inflammasome in lung injury inflammation and fibrosisQ46121594
ASC controls IFN-γ levels in an IL-18-dependent manner in caspase-1-deficient mice infected with Francisella novicidaQ47703279
Multiple sclerosis: cytokine receptors on oligodendrocytes predict innate regulationQ48101693
Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury.Q48515139
Cerebrospinal fluid and serum uric acid levels in patients with multiple sclerosis.Q48586779
IL-18 in patients with multiple sclerosisQ48795988
Uric acid levels in sera from patients with multiple sclerosis.Q48929988
Single-cell analysis of cytokine production shows different immune profiles in multiple sclerosis patients with active or quiescent diseaseQ57911977
The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapyQ60981654
Tumor necrosis factor and interleukin-1 in the CSF and sera of patients with multiple sclerosisQ68043629
Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosisQ70114371
Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligandQ73035541
Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosisQ74136791
Increased serum levels of interleukin-18 in patients with multiple sclerosisQ74250754
Interleukin 1 genotypes in multiple sclerosis and relationship to disease severityQ74570667
IL-18 is linked to raised IFN-gamma in multiple sclerosis and is induced by activated CD4(+) T cells via CD40-CD40 ligand interactionsQ77963029
Serum uric acid level in patients with relapsing-remitting multiple sclerosisQ86488871
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmultiple sclerosisQ8277
inflammasome complexQ412405
primary progressive multiple sclerosisQ18553470
P304page(s)983
P577publication date2018-05-04
P1433published inFrontiers in ImmunologyQ27723748
P1476titleMonosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis
P478volume9

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Q90055129Imaging Flow Cytometry Protocols for Examining Phagocytosis of Microplastics and Bioparticles by Immune Cells of Aquatic Animalscites workP2860

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