| scholarly article | Q13442814 |
| P2093 | author name string | Makoto Inoue | |
| Mari L Shinohara | |||
| P2860 | cites work | Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome | Q24291856 |
| Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes | Q24298360 | ||
| The inflammasomes | Q24304087 | ||
| NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder | Q24317771 | ||
| Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells | Q24523640 | ||
| New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes | Q24613164 | ||
| Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization | Q24631966 | ||
| Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica | Q24649598 | ||
| A role for mitochondria in NLRP3 inflammasome activation | Q28131794 | ||
| Gout-associated uric acid crystals activate the NALP3 inflammasome | Q28131797 | ||
| The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease | Q28207482 | ||
| Cryopyrin activates the inflammasome in response to toxins and ATP | Q28291313 | ||
| CC chemokine receptor 2 is critical for induction of experimental autoimmune encephalomyelitis | Q28587371 | ||
| Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis | Q28755978 | ||
| Pro-inflammatory programmed cell death | Q29300293 | ||
| Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome | Q29547419 | ||
| The NALP3 inflammasome is involved in the innate immune response to amyloid-beta | Q29615595 | ||
| Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration | Q29615596 | ||
| Inflammasomes in health and disease | Q29616356 | ||
| NLRP3 inflammasome activation: The convergence of multiple signalling pathways on ROS production? | Q29619524 | ||
| Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites | Q30492842 | ||
| NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis | Q30519470 | ||
| COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord | Q33235278 | ||
| T-bet-dependent expression of osteopontin contributes to T cell polarization | Q34144801 | ||
| Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis | Q34401745 | ||
| Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients | Q34606170 | ||
| Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. | Q35103371 | ||
| NLRP3 inflammasomes link inflammation and metabolic disease | Q35151726 | ||
| Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study | Q35454481 | ||
| A role for caspase-1 and -3 in the pathology of experimental allergic encephalomyelitis : inflammation versus degeneration | Q35747722 | ||
| Blocking adhesion molecules as therapy for multiple sclerosis: natalizumab | Q36148448 | ||
| CATERPILLERs, pyrin and hereditary immunological disorders | Q36405072 | ||
| Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome | Q36431053 | ||
| NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses | Q36670359 | ||
| Multiple sclerosis: longitudinal measurement of interleukin-1 receptor antagonist | Q36902610 | ||
| Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. | Q37059149 | ||
| Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis. | Q37114231 | ||
| Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis | Q37121507 | ||
| Regulation of T-helper-cell lineage development by osteopontin: the inside story | Q37354848 | ||
| NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens | Q37524804 | ||
| Signaling by ROS drives inflammasome activation | Q37702144 | ||
| The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond | Q37729538 | ||
| Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases | Q37866365 | ||
| The NLRP3 inflammasome in health and disease: the good, the bad and the ugly | Q37901519 | ||
| Serum uric acid levels in patients with multiple sclerosis: a meta-analysis | Q37983970 | ||
| The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. | Q39861713 | ||
| Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis. | Q40477272 | ||
| Caspase-1 expression in multiple sclerosis plaques and cultured glial cells | Q40733610 | ||
| Interleukin-1 beta maturation and release in response to ATP and nigericin. Evidence that potassium depletion mediated by these agents is a necessary and common feature of their activity | Q42606557 | ||
| A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. | Q42767100 | ||
| Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity. | Q43291517 | ||
| Combined effect of HLA-DRB1*1501 and interleukin-1 receptor antagonist gene allele 2 in susceptibility to relapsing/remitting multiple sclerosis | Q44151233 | ||
| Genetic polymorphisms of IL-1beta and IL-1 receptor antagonist in association with multiple sclerosis in Japanese patients | Q44816981 | ||
| Critical roles of CXC chemokine ligand 16/scavenger receptor that binds phosphatidylserine and oxidized lipoprotein in the pathogenesis of both acute and adoptive transfer experimental autoimmune encephalomyelitis | Q44987450 | ||
| Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin. | Q46007698 | ||
| Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence | Q46064734 | ||
| Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. | Q46078718 | ||
| Differential induction of interleukin-12, interleukin-18, and interleukin-1beta converting enzyme mRNA in experimental autoimmune encephalomyelitis of the Lewis rat. | Q46238342 | ||
| Interaction between glutamate signalling and immune attack in damaging oligodendrocytes | Q46478463 | ||
| MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study | Q47877446 | ||
| Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells | Q47973614 | ||
| Neutralizing antibodies to IFN-gamma-inducing factor prevent experimental autoimmune encephalomyelitis | Q48339467 | ||
| Brain multiple sclerosis-like lesions in a patient with Muckle-Wells syndrome | Q48434400 | ||
| The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence | Q48797548 | ||
| Gain-of-function of P2X7 receptor gene variants in multiple sclerosis. | Q50526479 | ||
| The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18 | Q53287408 | ||
| Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity. | Q54379135 | ||
| Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling | Q57080628 | ||
| Monocytes P2X7 purinergic receptor is modulated by glatiramer acetate in multiple sclerosis | Q57267910 | ||
| Gelatinase B, PECAM-1 and MCP-3 gene polymorphisms in Belgian multiple sclerosis | Q57584461 | ||
| P2X7 Receptor Blockade Prevents ATP Excitotoxicity in Oligodendrocytes and Ameliorates Experimental Autoimmune Encephalomyelitis | Q57975135 | ||
| Circulating serum levels of IL-1ra in patients with relapsing remitting multiple sclerosis are normal during remission phases but significantly increased either during exacerbations or in response to IFN-beta treatment | Q71311050 | ||
| Increased cathepsin B activity in multiple sclerosis brain | Q71748953 | ||
| Interleukin-1 receptor antagonist gene polymorphism and multiple sclerosis | Q71756319 | ||
| Interleukin 1 receptor antagonist (IL-1ra) in multiple sclerosis | Q73539375 | ||
| Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling | Q73589598 | ||
| A study of interleukin-1 cluster genes in susceptibility to and severity of multiple sclerosis | Q73779592 | ||
| Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis | Q73800880 | ||
| Production of IL-1beta and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis | Q74136791 | ||
| IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells | Q74279845 | ||
| Distinct chemokine receptor and cytokine expression profile in secondary progressive MS | Q74844776 | ||
| Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice | Q77671445 | ||
| Caspase-1 regulates the inflammatory process leading to autoimmune demyelination | Q78145110 | ||
| Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation | Q80102514 | ||
| P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | inflammasome complex | Q412405 |
| P304 | page(s) | 859145 | |
| P577 | publication date | 2013-01-08 | |
| P1433 | published in | Autoimmune Diseases | Q26842451 |
| P1476 | title | NLRP3 Inflammasome and MS/EAE. | |
| P478 | volume | 2013 |
| Q89892713 | A C-terminal peptide from type I interferon protects the retina in a mouse model of autoimmune uveitis |
| Q55211956 | A20 critically controls microglia activation and inhibits inflammasome-dependent neuroinflammation. |
| Q50220296 | Activating cannabinoid receptor 2 alleviates pathogenesis of experimental autoimmune encephalomyelitis via activation of autophagy and inhibiting NLRP3 inflammasome |
| Q36846937 | Anti-Apoptotic and Pro-Survival Effect of Alpinate Oxyphyllae Fructus (AOF) in a d-Galactose-Induced Aging Heart. |
| Q52568403 | Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation. |
| Q64916145 | Caspase-1 inhibition prevents glial inflammasome activation and pyroptosis in models of multiple sclerosis. |
| Q40509061 | Central CCL2 signaling onto MCH neurons mediates metabolic and behavioral adaptation to inflammation. |
| Q36492709 | Chlamydial plasmid-encoded protein pORF5 induces production of IL-1β and IL-18 via NALP3 inflammasome activation and p38 MAPK pathway |
| Q36340032 | Fetuin-A deficiency protects mice from Experimental Autoimmune Encephalomyelitis (EAE) and correlates with altered innate immune response |
| Q90725950 | Inflammasome Priming Mediated via Toll-Like Receptors 2 and 4, Induces Th1-Like Regulatory T Cells in De Novo Autoimmune Hepatitis |
| Q64901156 | Inflammasomes in neuroinflammatory and neurodegenerative diseases. |
| Q55378559 | Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis. |
| Q51063983 | Multiple sclerosis: association with the interleukin-1 gene family polymorphisms in the Turkish population. |
| Q47763288 | NLRP3 Inflammasome Activation in a Transgenic Amyotrophic Lateral Sclerosis Model |
| Q35668969 | NLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes |
| Q36056835 | NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. |
| Q27023333 | NLRP3 inflammasome and its inhibitors: a review |
| Q90123505 | NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity |
| Q52624393 | New insights into Nod-like receptors (NLRs) in liver diseases. |
| Q37661367 | Oxidative and Nitrosative Stress and Immune-Inflammatory Pathways in Patients with Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS). |
| Q47556931 | Relevance of the NLRP3 Inflammasome in the Pathogenesis of Chronic Liver Disease |
| Q55057482 | Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals. |
| Q52151935 | S100B as a Potential Biomarker and Therapeutic Target in Multiple Sclerosis. |
| Q36298402 | Silencing of Abcc8 or inhibition of newly upregulated Sur1-Trpm4 reduce inflammation and disease progression in experimental autoimmune encephalomyelitis |
| Q89020701 | Structural Insights of Benzenesulfonamide Analogues as NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization |
| Q57049900 | Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin |
| Q58104043 | TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation |
| Q58764700 | Targeting NLRP3 Inflammasome in the Treatment of CNS Diseases |
| Q55436021 | The Absent in Melanoma 2-Like Receptor IFN-Inducible Protein 16 as an Inflammasome Regulator in Systemic Lupus Erythematosus: The Dark Side of Sensing Microbes. |
| Q89094836 | The Effects of IFN-β 1a on the Expression of Inflammasomes and Apoptosis-Associated Speck-Like Proteins in Multiple Sclerosis Patients |
| Q39036848 | The inflammasome as a target for pain therapy |
| Q40147920 | Unified Modeling of Familial Mediterranean Fever and Cryopyrin Associated Periodic Syndromes |
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