Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation.

scientific article published on 8 June 2018

Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/CANCERS10060190
P932PMC publication ID6025049
P698PubMed publication ID29890660

P50authorHiroaki KataokaQ60976407
P2093author name stringTakahiro Nagai
Naoki Terada
Yoshinobu Toda
Shoichiro Mukai
Toshiyuki Kamoto
Hiromasa Sakamoto
Noboru Shibasaki
Satoru Sugie
Koji Yamasaki
Kozue Nakahara
Toyoharu Kamibeppu
P2860cites workPrognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinomaQ46248263
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Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial.Q50139906
Expression of human kallikrein 1-related peptidase 4 (KLK4) and MET phosphorylation in prostate cancer tissue: immunohistochemical analysisQ53220940
Clinical relevance of hepsin and hepatocyte growth factor activator inhibitor type 2 expression in renal cell carcinoma.Q55043279
Hepatocyte growth factor as mitogen, motogen and morphogen, and its roles in organ regenerationQ71943753
Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitorQ24322087
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Selective Allosteric Inhibition of MMP9 Is Efficacious in Preclinical Models of Ulcerative Colitis and Colorectal CancerQ27306938
Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formulaQ28263575
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
High expression of the Met receptor in prostate cancer metastasis to boneQ34163761
Drug development of MET inhibitors: targeting oncogene addiction and expedienceQ34782774
Matriptase: potent proteolysis on the cell surfaceQ34809525
Matriptase and MET are prominently expressed at the site of bone metastasis in renal cell carcinoma: immunohistochemical analysisQ34854941
HAI-2 suppresses the invasive growth and metastasis of prostate cancer through regulation of matriptase.Q35041020
The intricate role of CXCR4 in cancerQ35067624
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Cabozantinib in chemotherapy-pretreated metastatic castration-resistant prostate cancer: results of a phase II nonrandomized expansion study.Q35252908
The MET receptor tyrosine kinase in invasion and metastasisQ36868644
Renal cell carcinoma bone metastasis--elucidating the molecular targetsQ36928033
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C-met inhibition blocks bone metastasis development induced by renal cancer stem cells.Q37564471
Differential Tumorigenic Potential and Matriptase Activation between PDGF B versus PDGF D in Prostate CancerQ37593021
Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasisQ37610695
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Acquired resistance mechanisms to tyrosine kinase inhibitors in lung cancer with activating epidermal growth factor receptor mutation--diversity, ductility, and destinyQ38021967
Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial.Q38859789
Strong expression association between matriptase and its substrate prostasin in breast cancerQ39523621
Presence of phosphorylated hepatocyte growth factor receptor/c-Met is associated with tumor progression and survival in patients with conventional renal cell carcinomaQ40242701
Establishment and characterization of a human renal carcinoma cell line MRT-1, with special reference to the production of serine proteinase inhibitorsQ41365940
A direct role for Met endocytosis in tumorigenesis.Q42809894
Interaction between human-breast cancer metastasis and bone microenvironment through activated hepatocyte growth factor/Met and beta-catenin/Wnt pathways.Q43115646
Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinomaQ43299263
Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs.Q44843363
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P921main subjectphosphorylationQ242736
P577publication date2018-06-08
P1433published inCancersQ27722963
P1476titleDysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation.
P478volume10

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