scholarly article | Q13442814 |
P2093 | author name string | Mark C Udey | |
Xu Feng | |||
Michael Lu | |||
Sohshi Morimura | |||
Chuan-Jin Wu | |||
P2860 | cites work | Molecular cloning of cDNA for matriptase, a matrix-degrading serine protease with trypsin-like activity | Q22010006 |
Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy | Q24292827 | ||
The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7 | Q24311535 | ||
Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice | Q24313255 | ||
EpCAM controls actomyosin contractility and cell adhesion by direct inhibition of PKC. | Q45373544 | ||
Intestinal deletion of Claudin-7 enhances paracellular organic solute flux and initiates colonic inflammation in mice | Q50600432 | ||
EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins | Q50794460 | ||
Genetic analysis of Italian patients with congenital tufting enteropathy | Q60679073 | ||
Biochemical analysis of a human epithelial surface antigen: differential cell expression and processing | Q67976400 | ||
Nuclear signalling by tumour-associated antigen EpCAM | Q24315870 | ||
Molecular cloning of cDNA for the human tumor-associated antigen CO-029 and identification of related transmembrane antigens | Q24557431 | ||
Identification of EpCAM as the gene for congenital tufting enteropathy | Q24647346 | ||
EpCAM (CD326) finding its role in cancer | Q24653692 | ||
Ep-CAM: a human epithelial antigen is a homophilic cell-cell adhesion molecule | Q24673345 | ||
Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes | Q28142811 | ||
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Q28239639 | ||
Claudin-7 regulates EpCAM-mediated functions in tumor progression | Q28566627 | ||
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected] | Q29618714 | ||
Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine | Q33732689 | ||
The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin | Q34070450 | ||
EpCAM is an endoderm-specific Wnt derepressor that licenses hepatic development | Q34332606 | ||
mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/β-catenin. | Q34499625 | ||
Transport via the transcytotic pathway makes prostasin available as a substrate for matriptase | Q34568634 | ||
The role of molecular remodeling in differential regulation of tight junction permeability | Q34617424 | ||
Functional analysis of a missense mutation in the serine protease inhibitor SPINT2 associated with congenital sodium diarrhea | Q35145031 | ||
Inflammation and disruption of the mucosal architecture in claudin-7-deficient mice | Q35705366 | ||
Matriptase protects against experimental colitis and promotes intestinal barrier recovery | Q35785774 | ||
Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis | Q35823094 | ||
Regulation of the intestinal epithelial barrier by the apical junctional complex | Q36388836 | ||
Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway | Q36760282 | ||
Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions | Q36796935 | ||
Zymogen activation, inhibition, and ectodomain shedding of matriptase | Q36991884 | ||
Regulation of epithelial cell adhesion and repulsion: role of endocytic recycling | Q37102047 | ||
Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway | Q37362059 | ||
Matriptase: a culprit in cancer? | Q37401353 | ||
Functional consequences of EpCam mutation in mice and men. | Q37575826 | ||
In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture. | Q37672580 | ||
The matriptase-prostasin proteolytic cascade in epithelial development and pathology | Q37986624 | ||
Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells | Q38274629 | ||
The role of EpCAM in physiology and pathology of the epithelium | Q38614359 | ||
Hepatocyte growth factor activation inhibitors (HAI-1 and HAI-2) regulate HGF-induced invasion of human breast cancer cells | Q40300349 | ||
Genetic characterization of congenital tufting enteropathy: epcam associated phenotype and involvement of SPINT2 in the syndromic form | Q43488017 | ||
Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis | Q44007860 | ||
Primary mouse small intestinal epithelial cell cultures | Q44695414 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 623-634 | |
P577 | publication date | 2017-01-17 | |
P1433 | published in | Journal of Clinical Investigation | Q3186904 |
P1476 | title | Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis | |
P478 | volume | 127 |
Q52588795 | Advances in Evaluation of Chronic Diarrhea in Infants. |
Q58582443 | Blocking the proteolytic activity of zymogen matriptase with antibody-based inhibitors |
Q61451740 | Conserved function of the matriptase-prostasin proteolytic cascade during epithelial morphogenesis |
Q55515387 | Dysregulated HAI-2 Plays an Important Role in Renal Cell Carcinoma Bone Metastasis through Ligand-Dependent MET Phosphorylation. |
Q93263869 | EPCAM mutation update: Variants associated with congenital tufting enteropathy and Lynch syndrome |
Q57071697 | Emerging clinical significance of claudin-7 in colorectal cancer: a review |
Q60920626 | Hepatocyte growth factor activator inhibitor-2 stabilizes Epcam and maintains epithelial organization in the mouse intestine |
Q54948226 | Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy. |
Q96640603 | Matriptase processing of APLP1 ectodomain alters its homodimerization |
Q48307273 | Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia |
Q57285991 | Regulation of epithelial migration by epithelial cell adhesion molecule requires its Claudin-7 interaction domain |
Q89709684 | SPINT2 inhibits proteases involved in activation of both influenza viruses and metapneumoviruses |
Q47171613 | The Kunitz Domain I of Hepatocyte Growth Factor Activator Inhibitor-2 Inhibits Matriptase Activity and Invasive Ability of Human Prostate Cancer Cells |
Q37719392 | The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss. |
Q42778244 | The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β amyloid |
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