| scholarly article | Q13442814 |
| P356 | DOI | 10.1161/01.RES.87.9.774 |
| P698 | PubMed publication ID | 11055981 |
| P50 | author | Donald M. Bers | Q40664240 |
| P2093 | author name string | K Schlotthauer | |
| P433 | issue | 9 | |
| P304 | page(s) | 774-780 | |
| P577 | publication date | 2000-10-01 | |
| P1433 | published in | Circulation Research | Q2599020 |
| P1476 | title | Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials | |
| P478 | volume | 87 |
| Q46356649 | A Dynamical Threshold for Cardiac Delayed Afterdepolarization-Mediated Triggered Activity |
| Q46882483 | A domain peptide of the cardiac ryanodine receptor regulates channel sensitivity to luminal Ca2+ via cytoplasmic Ca2+ sites |
| Q35936858 | Abnormal termination of Ca2+ release is a common defect of RyR2 mutations associated with cardiomyopathies |
| Q44970472 | Action potential duration determines sarcoplasmic reticulum Ca2+ reloading in mammalian ventricular myocytes |
| Q36412283 | Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes. |
| Q40454136 | Altered Ca2+ handling and myofilament desensitization underlie cardiomyocyte performance in normothermic and hyperthermic heat-acclimated rat hearts. |
| Q35679654 | Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes |
| Q52654918 | Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias. |
| Q46016672 | Approximate analytical solutions for excitation and propagation in cardiac tissue. |
| Q30490734 | Arrhythmogenic consequences of intracellular calcium waves |
| Q37272739 | Arrhythmogenic substrates in myocardial infarct |
| Q37799693 | Atrial Fibrillation-The Final Frontier |
| Q27319107 | Atrial SERCA2a Overexpression Has No Affect on Cardiac Alternans but Promotes Arrhythmogenic SR Ca2+ Triggers |
| Q37726503 | Ca handling during excitation-contraction coupling in heart failure |
| Q51612393 | Ca(2+) wave probability is determined by the balance between SERCA2-dependent Ca(2+) reuptake and threshold SR Ca(2+) content. |
| Q36889210 | Ca2+ stores regulate ryanodine receptor Ca2+ release channels via luminal and cytosolic Ca2+ sites |
| Q35095089 | Calcium and arrhythmogenesis |
| Q35189269 | Calcium and cardiac arrhythmias: DADs, EADs, and alternans |
| Q46141791 | Calcium-Dependent Arrhythmogenic Foci Created by Weakly Coupled Myocytes in the Failing Heart |
| Q37777871 | Calmodulin kinase II, sarcoplasmic reticulum Ca2+ leak, and atrial fibrillation |
| Q34977809 | Cardiac ankyrins in health and disease |
| Q38116972 | Cardiovascular effects of antimuscarinic agents in overactive bladder. |
| Q35707246 | Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release |
| Q38065639 | Ca²⁺ waves in the heart |
| Q38677208 | Ca²⁺-induced delayed afterdepolarizations are triggered by dyadic subspace Ca2²⁺ affirming that increasing SERCA reduces aftercontractions |
| Q28483390 | Cell model of catecholaminergic polymorphic ventricular tachycardia reveals early and delayed afterdepolarizations |
| Q73627217 | Cellular electrophysiology of canine pulmonary vein cardiomyocytes: action potential and ionic current properties |
| Q35622415 | Chasing cardiac physiology and pathology down the CaMKII cascade |
| Q43164861 | Chasing with ranolazine pulmonary vein afterpotentials before it's too late |
| Q35195291 | Coordinating electrical activity of the heart: ankyrin polypeptides in human cardiac disease |
| Q74695277 | Cytosolic Ca2+ triggers early afterdepolarizations and Torsade de Pointes in rabbit hearts with type 2 long QT syndrome |
| Q36037969 | Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia |
| Q34201123 | Dantrolene suppresses spontaneous Ca2+ release without altering excitation-contraction coupling in cardiomyocytes of aged mice |
| Q53733547 | Dantrolene suppresses ventricular ectopy and arrhythmogenicity with acute myocardial infarction in a langendorff-perfused pacing-induced heart failure rabbit model. |
| Q92226110 | Delayed afterdepolarization-induced triggered activity in cardiac purkinje cells mediated through cytosolic calcium diffusion waves |
| Q36094927 | Delayed afterdepolarizations generate both triggers and a vulnerable substrate promoting reentry in cardiac tissue |
| Q34203735 | Depolarization of cardiac membrane potential synchronizes calcium sparks and waves in tissue |
| Q34012761 | Detection, properties, and frequency of local calcium release from the sarcoplasmic reticulum in teleost cardiomyocytes |
| Q34088867 | Differences in the regulation of RyR2 from human, sheep, and rat by Ca²⁺ and Mg²⁺ in the cytoplasm and in the lumen of the sarcoplasmic reticulum |
| Q35094366 | Distinguishing between overdrive excited and suppressed ventricular beats in guinea pig ventricular myocardium |
| Q38104947 | Do t-tubules play a role in arrhythmogenesis in cardiac ventricular myocytes? |
| Q42596728 | Dual Vm/Ca imaging of premature ventricular contractions: bridging the gap of anatomical scales |
| Q88880489 | Dysfunctional Nav1.5 channels due to SCN5A mutations |
| Q33559348 | Dysregulated sarcoplasmic reticulum calcium release: potential pharmacological target in cardiac disease |
| Q37809309 | Dyssynchrony of Ca2+ release from the sarcoplasmic reticulum as subcellular mechanism of cardiac contractile dysfunction. |
| Q44559053 | Effects of Na+/Ca2+ exchange induced by SR Ca2+ release on action potentials and afterdepolarizations in guinea pig ventricular myocytes |
| Q37344147 | Effects of unipolar stimulation on voltage and calcium distributions in the isolated rabbit heart |
| Q36331025 | Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation |
| Q45984923 | Estimating the probabilities of rare arrhythmic events in multiscale computational models of cardiac cells and tissue. |
| Q34629553 | Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia |
| Q38850764 | Functional Impact of Ryanodine Receptor Oxidation on Intracellular Calcium Regulation in the Heart |
| Q30481651 | Generation and escape of local waves from the boundary of uncoupled cardiac tissue |
| Q42583563 | Heart, calcium and time. |
| Q38774693 | High-Throughput Phenotyping of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Neurons Using Electric Field Stimulation and High-Speed Fluorescence Imaging |
| Q36219325 | Increased Energy Demand during Adrenergic Receptor Stimulation Contributes to Ca(2+) Wave Generation |
| Q44731083 | Induced automaticity in isolated rat atrial cells by incorporation of a stretch-activated conductance |
| Q58803017 | Influence of Amiodarone and Dronedarone on the Force-Interval Dependence of Rat Myocardium |
| Q28308142 | Inherited dysfunction of sarcoplasmic reticulum Ca2+ handling and arrhythmogenesis |
| Q35737061 | Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice |
| Q44686941 | Inhibition of the sarcoplasmic reticulum Ca2+ pump with thapsigargin to estimate the contribution of Na+-Ca2+ exchange to ventricular myocyte relaxation |
| Q33279720 | Inositol-1,4,5-trisphosphate-mediated spontaneous activity in mouse embryonic stem cell-derived cardiomyocytes |
| Q35872466 | Instabilities of the resting state in a mathematical model of calcium handling in cardiac myocytes |
| Q34680310 | Interplay of ryanodine receptor distribution and calcium dynamics |
| Q41863784 | Intracellular Ca2+ oscillations, a potential pacemaking mechanism in early embryonic heart cells |
| Q43227813 | Intracellular Ca2+ waves, afterdepolarizations, and triggered arrhythmias |
| Q57799737 | Ionic and cellular mechanisms underlying TBX5/PITX2 insufficiency-induced atrial fibrillation: Insights from mathematical models of human atrial cells |
| Q39994597 | Ionic mechanism of shock-induced arrhythmias: role of intracellular calcium |
| Q39542247 | K201 (JTV-519) alters the spatiotemporal properties of diastolic Ca(2+) release and the associated diastolic contraction during β-adrenergic stimulation in rat ventricular cardiomyocytes |
| Q36338145 | KChIP2 regulates the cardiac Ca2+ transient and myocyte contractility by targeting ryanodine receptor activity. |
| Q41108695 | Limited role of Ca(2+)-activated Cl(-) current in early afterdepolarisations |
| Q42145637 | Local β-adrenergic stimulation overcomes source-sink mismatch to generate focal arrhythmia |
| Q38568707 | Mechanism, diagnosis, and treatment of outflow tract tachycardia |
| Q30843252 | Mechanisms Underlying the Emergence of Post-acidosis Arrhythmia at the Tissue Level: A Theoretical Study. |
| Q33930892 | Mechanisms of sudden cardiac death. |
| Q37717622 | Minimizing repolarization-related proarrhythmic risk in drug development and clinical practice. |
| Q30706294 | Multimodal SHG-2PF Imaging of Microdomain Ca2+-Contraction Coupling in Live Cardiac Myocytes |
| Q38048564 | No rest for the weary: diastolic calcium homeostasis in the normal and failing myocardium |
| Q36992635 | Non-β-blocking R-carvedilol enantiomer suppresses Ca2+ waves and stress-induced ventricular tachyarrhythmia without lowering heart rate or blood pressure. |
| Q43152332 | Nonuniform Ca2+ transients in arrhythmogenic Purkinje cells that survive in the infarcted canine heart. |
| Q35755909 | Novel Analysis Software for Detecting and Classifying Ca2+ Transient Abnormalities in Stem Cell-Derived Cardiomyocytes |
| Q37495839 | Novel carvedilol analogues that suppress store-overload-induced Ca2+ release |
| Q35825873 | Novel therapeutic approaches for heart failure by normalizing calcium cycling |
| Q82254495 | Optical mapping study of blebbistatin-induced chaotic electrical activities in isolated rat atrium preparations |
| Q34573114 | Orphaned ryanodine receptors in the failing heart. |
| Q90361067 | Oxidation of ryanodine receptor after ischemia-reperfusion increases propensity of Ca2+ waves during β-adrenergic receptor stimulation |
| Q39342948 | Pathophysiology of ventricular tachyarrhythmias : From automaticity to reentry |
| Q28067569 | Patient Specific Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Drug Development and Screening In Catecholaminergic Polymorphic Ventricular Tachycardia |
| Q37396106 | Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice |
| Q43920140 | Potassium currents in the heart: functional roles in repolarization, arrhythmia and therapeutics |
| Q42579234 | Racing to the flatline: heart rate and β-adrenergic stimulation quicken the pace |
| Q45066793 | Reactive oxygen species contribute to the development of arrhythmogenic Ca²⁺ waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes |
| Q34352507 | Regulation of cardiac sarcoplasmic reticulum Ca release by luminal [Ca] and altered gating assessed with a mathematical model. |
| Q37282970 | Remodelling of cardiac repolarization: how homeostatic responses can lead to arrhythmogenesis. |
| Q37644605 | Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies |
| Q37325502 | Revisiting K(+) channel-dependent electrical remodeling in the border zone |
| Q44596974 | Role of Ca2+-activated Cl- current during proarrhythmic early afterdepolarizations in sheep and human ventricular myocytes. |
| Q51892922 | Role of Ca2+-dependent Cl- current on delayed afterdepolarizations. A simulation study. |
| Q34049927 | Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts |
| Q61479656 | Sarcoplasmic reticulum and L-type Ca²⁺ channel activity regulate the beat-to-beat stability of calcium handling in human atrial myocytes |
| Q89408767 | Simultaneous recordings of action potentials and calcium transients from human induced pluripotent stem cell derived cardiomyocytes |
| Q35197369 | Single-sensor system for spatially resolved, continuous, and multiparametric optical mapping of cardiac tissue |
| Q36356723 | Slow Calcium-Depolarization-Calcium waves may initiate fast local depolarization waves in ventricular tissue. |
| Q34099038 | So Little Source, So Much Sink: Requirements for Afterdepolarizations to Propagate in Tissue |
| Q47365952 | Sorcin ablation plus β-adrenergic stimulation generate an arrhythmogenic substrate in mouse ventricular myocytes. |
| Q40981831 | Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II. |
| Q46017004 | Spontaneous atrial fibrillation initiated by triggered activity near the pulmonary veins in aged rats subjected to glycolytic inhibition. |
| Q37406349 | Spontaneous calcium release in tissue from the failing canine heart |
| Q42174287 | Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias. |
| Q27302108 | Stochastic spontaneous calcium release events trigger premature ventricular complexes by overcoming electrotonic load |
| Q49912067 | Stress Signaling JNK2 Crosstalk with CaMKII Underlies Enhanced Atrial Arrhythmogenesis |
| Q31026467 | Stretch and quick release of rat cardiac trabeculae accelerates Ca2+ waves and triggered propagated contractions |
| Q30430362 | Synergy between CaMKII Substrates and β-Adrenergic Signaling in Regulation of Cardiac Myocyte Ca2+ Handling |
| Q40793419 | TNF-alpha and IL-1beta increase Ca2+ leak from the sarcoplasmic reticulum and susceptibility to arrhythmia in rat ventricular myocytes |
| Q34460234 | TRPC3 contributes to regulation of cardiac contractility and arrhythmogenesis by dynamic interaction with NCX1. |
| Q37480953 | Targeted SERCA2a gene expression identifies molecular mechanism and therapeutic target for arrhythmogenic cardiac alternans |
| Q43967626 | The CPVT-associated RyR2 mutation G230C enhances store overload-induced Ca2+ release and destabilizes the N-terminal domains |
| Q38821307 | The Significance of the Late Na+ Current for Arrhythmia Induction and the Therapeutic Antiarrhythmic Potential of Ranolazine |
| Q37345048 | The arrhythmogenic consequences of increasing late INa in the cardiomyocyte |
| Q34775590 | The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice. |
| Q26823149 | The role of late I Na in development of cardiac arrhythmias |
| Q37799958 | The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications |
| Q34725308 | The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias |
| Q35743226 | The statistics of calcium-mediated focal excitations on a one-dimensional cable |
| Q34729959 | The timing statistics of spontaneous calcium release in cardiac myocytes |
| Q54326472 | Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito) through an IRF3-dependent and MyD88-independent pathway. |
| Q46241479 | Transverse tubular network structures in the genesis of intracellular calcium alternans and triggered activity in cardiac cells |
| Q35758055 | Triggered activity and atrial fibrillation |
| Q37639070 | Trimeric intracellular cation channels and sarcoplasmic/endoplasmic reticulum calcium homeostasis |
| Q36093938 | Twenty years of calcium imaging: cell physiology to dye for. |
| Q91814957 | Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic |
| Q30497201 | Variability in Timing of Spontaneous Calcium Release in the Intact Rat Heart Is Determined by the Time Course of Sarcoplasmic Reticulum Calcium Load |
| Q33850215 | Verapamil suppresses cardiac alternans and ventricular arrhythmias in acute myocardial ischemia via ryanodine receptor inhibition |
| Q37633116 | X-ROS signaling in the heart and skeletal muscle: stretch-dependent local ROS regulates [Ca²⁺]i |
| Q84987760 | β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation |
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