HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

scholarly article by Laura Menotti published in June 2018

HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/V10070352
P932PMC publication ID6070899
P698PubMed publication ID29966356

P50authorGabriella Campadelli-FiumeQ21062117
Valentina GattaQ57123026
Biljana PetrovicQ57314115
Laura MenottiQ117248756
Elisa AvitabileQ124273094
P2093author name stringPaolo Malatesta
P2860cites workOncolytic viruses as therapeutic cancer vaccinesQ21245758
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IL-12 Expressing oncolytic herpes simplex virus promotes anti-tumor activity and immunologic control of metastatic ovarian cancer in mice.Q30355682
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discoveryQ33479152
Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.Q33621028
Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL.Q33730717
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Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteinsQ33812868
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomasQ33881165
ICP34.5 deleted herpes simplex virus with enhanced oncolytic, immune stimulating, and anti-tumour propertiesQ34178661
Breast tumor cell lines from pleural effusionsQ34209613
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Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced MelanomaQ34478015
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A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptorsQ34648103
Production of bioactive soluble interleukin-15 in complex with interleukin-15 receptor alpha from a conditionally-replicating oncolytic HSV-1Q35060701
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A double mutation in glycoprotein gB compensates for ineffective gD-dependent initiation of herpes simplex virus type 1 infectionQ41806893
TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of RhabdomyosarcomaQ42373489
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Anti-epidermal growth factor receptor (EGFR) antibodies overcome resistance of ovarian cancer cells to targeted therapy and natural cytotoxicityQ36321894
Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastasesQ36544212
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Combination of oncolytic herpes simplex viruses armed with angiostatin and IL-12 enhances antitumor efficacy in human glioblastoma models.Q36879211
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Recombinant Parvoviruses Armed to Deliver CXCL4L1 and CXCL10 Are Impaired in Their Antiangiogenic and Antitumoral Effects in a Kaposi Sarcoma Tumor Model Due To the Chemokines' Interference with the Virus CycleQ38723279
The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma.Q38819651
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Systemic versus local responses in melanoma patients treated with talimogene laherparepvec from a multi-institutional phase II study.Q39002223
Epstein-Barr virus infection induces miR-21 in terminally differentiated malignant B cellsQ39036600
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OPTIM trial: a Phase III trial of an oncolytic herpes virus encoding GM-CSF for unresectable stage III or IV melanomaQ39866378
Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.Q39953338
Genetics of natural resistance to herpesvirus infections in miceQ39958787
The combination of NK and CD8+T cells with CCL20/IL15-armed oncolytic adenoviruses enhances the growth suppression of TERT-positive tumor cellsQ40144926
Oncolytic measles virus encoding interleukin-12 mediates potent antitumor effects through T cell activationQ40200208
Herpes simplex virus 1 recombinant virions exhibiting the amino terminal fragment of urokinase-type plasminogen activator can enter cells via the cognate receptorQ40350509
Novel role of prostate-specific membrane antigen in suppressing prostate cancer invasiveness.Q40459690
The herpes simplex virus JMP mutant enters receptor-negative J cells through a novel pathway independent of the known receptors nectin1, HveA, and nectin2.Q40567844
Noninvasive Monitoring of Glioma Growth in the Mouse.Q41201141
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectoncolytic virusQ1560099
virologyQ7215
P304page(s)352
P577publication date2018-06-30
P1433published inVirusesQ7935305
P1476titleHSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses
P478volume10

Reverse relations

cites work (P2860)
Q56348401A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors
Q91521080Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model
Q89682703Oncolytic Virus Encoding a Master Pro-Inflammatory Cytokine Interleukin 12 in Cancer Immunotherapy
Q63246477Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells
Q90171041Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis

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