| Q83028903 | 6-Benzylamino 4-oxo-1,4-dihydro-1,8-naphthyridines and 4-oxo-1,4-dihydroquinolines as HIV integrase inhibitors |
| Q43793978 | A three-component coupling approach to cyclopentanoids. |
| Q35578234 | Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target. |
| Q57283092 | Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis |
| Q48507411 | Accelerated bottom-up drug design platform enables the discovery of novel stearoyl-CoA desaturase 1 inhibitors for cancer therapy |
| Q26829985 | Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes |
| Q80799707 | Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 1: Identification and synthesis of phenyl-tetrazolyl acetophenones |
| Q40500712 | Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 2: 4-thiopyridyl acetophenones as non-tetrazole containing mGlu2 receptor potentiators. |
| Q37660615 | Arylmethylamino steroids as antiparasitic agents |
| Q35201557 | Benzodiazepinone derivatives protect against endoplasmic reticulum stress-mediated cell death in human neuronal cell lines |
| Q92034651 | Boosting NAD+ with a small molecule that activates NAMPT |
| Q42791381 | Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. |
| Q36323683 | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. |
| Q79333759 | Diaryl substituted pyrazoles as potent CCR2 receptor antagonists |
| Q42715690 | Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor |
| Q49646377 | Discovery of 5-((5-chloro-2-methoxyphenyl)sulfonamido)nicotinamide (SBI-425), a potent and orally bioavailable tissue-nonspecific alkaline phosphatase (TNAP) inhibitor. |
| Q34409107 | Discovery of ML314, a Brain Penetrant Non-Peptidic β-Arrestin Biased Agonist of the Neurotensin NTR1 Receptor. |
| Q35623355 | Discovery of ML358, a Selective Small Molecule Inhibitor of the SKN-1 Pathway Involved in Drug Detoxification and Resistance in Nematodes. |
| Q34701285 | Discovery of Sulfonamidebenzamides as Selective Apoptotic CHOP Pathway Activators of the Unfolded Protein Response |
| Q92475015 | Discovery of β-Arrestin Biased, Orally Bioavailable, and CNS Penetrant Neurotensin Receptor 1 (NTR1) Allosteric Modulators |
| Q45765840 | Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase. |
| Q37635841 | Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity |
| Q43636539 | Formation of vinyl halides via a ruthenium-catalyzed three-component coupling. |
| Q61443767 | Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies |
| Q36249040 | HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter |
| Q36376028 | High-throughput screening and bioinformatic analysis to ascertain compounds that prevent saturated fatty acid-induced β-cell apoptosis. |
| Q28264283 | High-throughput screening for small-molecule inhibitors of plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase |
| Q91641819 | Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells |
| Q42000525 | Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes. |
| Q37502653 | Imidazole-derived agonists for the neurotensin 1 receptor. |
| Q91064225 | Inhibition of Tissue-Nonspecific Alkaline Phosphatase Attenuates Ectopic Mineralization in the Abcc6-/- Mouse Model of PXE but Not in the Enpp1 Mutant Mouse Models of GACI |
| Q34433459 | Inhibition of melanoma development in the Nras((Q61K)) ::Ink4a(-/-) mouse model by the small molecule BI-69A11. |
| Q34824356 | Inhibitors of tissue-nonspecific alkaline phosphatase (TNAP): from hits to leads. |
| Q37099122 | ML314: A Biased Neurotensin Receptor Ligand for Methamphetamine Abuse |
| Q30848149 | Nimbolide targets BCL2 and induces apoptosis in preclinical models of Waldenströms macroglobulinemia |
| Q46274127 | Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia |
| Q36575566 | PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically |
| Q35525230 | Pathophysiological role of vascular smooth muscle alkaline phosphatase in medial artery calcification |
| Q34263938 | Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2. |
| Q38031831 | Recent progress in the synthesis and characterization of group II metabotropic glutamate receptor allosteric modulators. |
| Q58747914 | Repurposing antimalarial aminoquinolines and related compounds for treatment of retinal neovascularization |
| Q36378135 | SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex |
| Q104794631 | Serine-threonine kinase TAO3-mediated trafficking of endosomes containing the invadopodia scaffold TKS5α promotes cancer invasion and tumor growth |
| Q42923567 | Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. |
| Q38764445 | TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling |
| Q92734544 | Targeting tumor phenotypic plasticity and metabolic remodeling in adaptive cross-drug tolerance |
| Q28271436 | Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces |