Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

scientific article published on 07 August 2018

Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7554/ELIFE.34593
P932PMC publication ID6080949
P698PubMed publication ID30082022

P50authorTadayuki ShimadaQ85266674
Michiko SaitoQ87970321
Kenji KohnoQ87970327
Naoyuki InagakiQ90782788
James S TrimmerQ56917322
P2093author name stringMichinori Toriyama
Wataru Yoshida
Rikiya Watanabe
Kentarou Baba
Colleen F Manning
P2860cites workShootin1 acts in concert with KIF20B to promote polarization of migrating neuronsQ24309631
Deleted in Colorectal Cancer (DCC) encodes a netrin receptorQ24313278
Shootin1-cortactin interaction mediates signal-force transduction for axon outgrowthQ27309290
The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidanceQ27334152
Efficient selection for high-expression transfectants with a novel eukaryotic vectorQ27860810
Cortactin: coupling membrane dynamics to cortical actin assemblyQ28199365
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) geneQ28236533
A brain serine/threonine protein kinase activated by Cdc42 and Rac1Q28249559
Focal adhesion kinase in netrin-1 signalingQ28288747
Spatial regulation of axonal glycoprotein expression on subsets of embryonic spinal neuronsQ28294361
Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neuronsQ28506696
Shootin1: A protein involved in the organization of an asymmetric signal for neuronal polarizationQ28512224
Shootin1 interacts with actin retrograde flow and L1-CAM to promote axon outgrowthQ28574182
Spatial and temporal activation of the small GTPases RhoA and Rac1 by the netrin-1 receptor UNC5a during neurite outgrowthQ28574805
Conversion of a signal into forces for axon outgrowth through Pak1-mediated shootin1 phosphorylationQ28575823
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansionQ28577458
Laminin stimulates and guides axonal outgrowth via growth cone myosin II activityQ28584768
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous systemQ29616040
Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact AdhesionsQ30357093
Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signalingQ30443470
Birefringence imaging directly reveals architectural dynamics of filamentous actin in living growth cones.Q30483070
UNC-6 (netrin) orients the invasive membrane of the anchor cell in C. elegansQ30485805
Netrin-1 attracts axons through FAK-dependent mechanotransductionQ30525348
A neuron-benign microfluidic gradient generator for studying the response of mammalian neurons towards axon guidance factorsQ30547676
Actin dynamics in growth cone motility and navigationQ30575707
UNC-6 (netrin) stabilizes oscillatory clustering of the UNC-40 (DCC) receptor to orient polarityQ30586748
Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activationQ32137183
Axon guidance: asymmetric signaling orients polarized outgrowth.Q33854522
A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attraction to repulsionQ33867499
Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance.Q33867701
Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesionQ33939231
Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidanceQ33996728
Netrins: versatile extracellular cues with diverse functionsQ34184016
Strength in the periphery: growth cone biomechanics and substrate rigidity response in peripheral and central nervous system neuronsQ34253602
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6.Q34332258
Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cordQ34332262
Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord.Q34559992
Traction dynamics of filopodia on compliant substrates.Q34901393
The trip of the tip: understanding the growth cone machinery.Q34976234
Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidanceQ35099606
Integration of shallow gradients of Shh and Netrin-1 guides commissural axons.Q35591107
Passive microfluidic chamber for long-term imaging of axon guidance in response to soluble gradients.Q35797291
Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane.Q35870286
FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth ConesQ36092322
The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling.Q36255245
Phenotypic analysis of mice completely lacking netrin 1.Q36285896
Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.Q36498043
Growth cone chemotaxisQ37059371
Mechanisms and molecules of neuronal wiring: a primerQ37814719
Calcium signaling in axon guidance.Q38223589
Rac1 and Cdc42 but not RhoA or Rho kinase activities are required for neurite outgrowth induced by the Netrin-1 receptor DCC (deleted in colorectal cancer) in N1E-115 neuroblastoma cellsQ38292096
Local sampling paints a global picture: Local concentration measurements sense direction in complex chemical gradients.Q38757426
Locally excitable Cdc42 signals steer cells during chemotaxis.Q38810077
Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.Q38818580
Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth coneQ39291439
The netrin-1 receptor DCC promotes filopodia formation and cell spreading by activating Cdc42 and Rac1.Q39454809
Cytoskeletal dynamics and nerve growthQ39584247
UNC-6/Netrin induces neuronal asymmetry and defines the site of axon formationQ40345230
The cell biology of neuronal navigationQ40721419
Adhesion molecules and inherited diseases of the human nervous systemQ41733275
Axon initiation and growth cone turning on bound protein gradients.Q42455214
Netrin-DCC signaling regulates corpus callosum formation through attraction of pioneering axons and by modulating Slit2-mediated repulsion.Q44567921
Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.Q44831766
Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulbQ44967956
Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal CordQ45345116
Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation.Q46430126
UNC-6, a laminin-related protein, guides cell and pioneer axon migrations in C. elegansQ48151727
The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development.Q48188608
Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout miceQ48188616
Quantifying biased response of axon to chemical gradient steepness in a microfluidic deviceQ48461303
The chemotactic hypothesis of Cajal: a century behindQ48531225
Axon Guidance by Gradients of a Target-Derived ComponentQ48546224
Identification of a shootin1 isoform expressed in peripheral tissuesQ48737668
Actin Migration Driven by Directional Assembly and Disassembly of Membrane-Anchored Actin Filaments.Q50254956
Grip and slip of L1-CAM on adhesive substrates direct growth cone haptotaxis.Q52688878
Haptotaxis and the Mechanism of Cell MotilityQ55062184
Complete Loss of Netrin-1 Results in Embryonic Lethality and Severe Axon Guidance Defects without Increased Neural Cell DeathQ57040916
A new chemotaxis assay shows the extreme sensitivity of axons to molecular gradientsQ57654926
Neuronal Chemotaxis: Chick Dorsal-Root Axons Turn Toward High Concentrations of Nerve Growth FactorQ66950239
L1/HNK-1 carbohydrate- and beta 1 integrin-dependent neural cell adhesion to laminin-1Q72996296
P4510describes a project that usesImageJQ1659584
P407language of work or nameEnglishQ1860
P577publication date2018-08-07
P1433published ineLifeQ2000008
P1476titleGradient-reading and mechano-effector machinery for netrin-1-induced axon guidance
P478volume7

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cites work (P2860)
Q92576959Molecular basis of the functions of the mammalian neuronal growth cone revealed using new methods
Q94678260Shootin-1 Is Required for Nervous System Development in Zebrafish
Q92757611Shootins mediate collective cell migration and organogenesis of the zebrafish posterior lateral line system
Q57812519The Role of Apoptotic Signaling in Axon Guidance

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