scholarly article | Q13442814 |
P50 | author | Michael Sheetz | Q1929376 |
Simon W. Moore | Q42559739 | ||
P2093 | author name string | Xian Zhang | |
Christopher D Lynch | |||
P2860 | cites work | Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases | Q24306594 |
Deleted in Colorectal Cancer (DCC) encodes a netrin receptor | Q24313278 | ||
DSCAM is a netrin receptor that collaborates with DCC in mediating turning responses to netrin-1 | Q24336510 | ||
Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src | Q24614033 | ||
Signaling from axon guidance receptors | Q24633929 | ||
Structural basis for the autoinhibition of focal adhesion kinase | Q24678318 | ||
Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors | Q28118661 | ||
Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin | Q28179787 | ||
A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications | Q28213193 | ||
Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene | Q28236533 | ||
Mechanism of blebbistatin inhibition of myosin II | Q28267628 | ||
A novel Cas family member, HEPL, regulates FAK and cell spreading | Q28267647 | ||
Focal adhesion kinase in netrin-1 signaling | Q28288747 | ||
Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate | Q28298433 | ||
Functional analysis of Src homology 3-encoding exon (exon 2) of p130Cas in primary fibroblasts derived from exon 2-specific knockout mice | Q28506747 | ||
p130cas but not paxillin is essential for Caco-2 intestinal epithelial cell spreading and migration on collagen IV | Q28564388 | ||
Role of focal adhesion kinase in flow-induced dilation of coronary arterioles | Q28564649 | ||
p130Cas, a substrate associated with v-Src and v-Crk, localizes to focal adhesions and binds to focal adhesion kinase | Q28572450 | ||
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion | Q28577458 | ||
Epidermal growth factor modulates tyrosine phosphorylation of p130Cas. Involvement of phosphatidylinositol 3'-kinase and actin cytoskeleton | Q28581924 | ||
Semaphorin 3A displays a punctate distribution on the surface of neuronal cells and interacts with proteoglycans in the extracellular matrix | Q28583845 | ||
Netrin-1 and DCC mediate axon guidance locally at the optic disc: loss of function leads to optic nerve hypoplasia | Q28585609 | ||
Myosin II activity regulates vinculin recruitment to focal adhesions through FAK-mediated paxillin phosphorylation | Q28586815 | ||
Cellular Strategies of Axonal Pathfinding | Q29029769 | ||
Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas | Q29030077 | ||
Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system | Q29616040 | ||
Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice | Q29617498 | ||
Cellular characterization of a novel focal adhesion kinase inhibitor | Q30443304 | ||
Dynamic molecular processes mediate cellular mechanotransduction | Q30453937 | ||
Talin depletion reveals independence of initial cell spreading from integrin activation and traction | Q30490335 | ||
Focal adhesion kinase is involved in mechanosensing during fibroblast migration | Q33944467 | ||
Dynamic conformational changes in the FERM domain of FAK are involved in focal-adhesion behavior during cell spreading and motility. | Q46125886 | ||
Netrins guide Drosophila commissural axons at short range. | Q47070391 | ||
The promotion of neurological recovery in the rat spinal cord crushed injury model by collagen-binding BDNF. | Q48087359 | ||
Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding. | Q50715822 | ||
Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. | Q50740752 | ||
Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex | Q58549456 | ||
A sensory role for neuronal growth cone filopodia | Q59067973 | ||
Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle | Q63385055 | ||
Tyrosine phosphorylation of pp125FAK and paxillin in aortic endothelial cells induced by mechanical strain | Q71435733 | ||
Glycosaminoglycan-binding properties and secondary structure of the C-terminus of netrin-1 | Q73754364 | ||
p130(Cas), an assembling molecule of actin filaments, promotes cell movement, cell migration, and cell spreading in fibroblasts | Q78128211 | ||
Dissection and culture of embryonic spinal commissural neurons | Q81131068 | ||
The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain | Q84617570 | ||
Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance | Q33996728 | ||
Netrins: versatile extracellular cues with diverse functions | Q34184016 | ||
Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration | Q34274897 | ||
The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans | Q34308728 | ||
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6. | Q34332258 | ||
Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord | Q34332262 | ||
Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction | Q34360468 | ||
Activation of FAK and Src are receptor-proximal events required for netrin signaling | Q34360478 | ||
Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages | Q34415326 | ||
Turning of retinal growth cones in a netrin-1 gradient mediated by the netrin receptor DCC. | Q34451947 | ||
cAMP-dependent growth cone guidance by netrin-1. | Q34451954 | ||
Direct evidence that growth cones pull | Q34533657 | ||
Axon guidance by diffusible chemoattractants: a gradient of netrin protein in the developing spinal cord. | Q34559992 | ||
The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons | Q34698265 | ||
Where the rubber meets the road: netrin expression and function in developing and adult nervous systems | Q35002876 | ||
Role of myosin II in axon outgrowth. | Q35087189 | ||
Signaling at the growth cone: ligand-receptor complexes and the control of axon growth and guidance | Q35099606 | ||
p130CAS is required for netrin signaling and commissural axon guidance | Q36054147 | ||
Integrin-mediated activation of MAP kinase is independent of FAK: evidence for dual integrin signaling pathways in fibroblasts | Q36254663 | ||
Heparin/heparan sulphate binding in the TGF-beta cytokine superfamily | Q36482149 | ||
Proteoglycans as modulators of axon guidance cue function. | Q36868917 | ||
Cell membrane mechanics | Q36888835 | ||
Netrins and their receptors | Q37082697 | ||
Focal adhesion kinase modulates cell adhesion strengthening via integrin activation | Q37175419 | ||
Stretchy proteins on stretchy substrates: the important elements of integrin-mediated rigidity sensing | Q37779877 | ||
Biophysics of substrate interaction: influence on neural motility, differentiation, and repair | Q37899109 | ||
Spatial and temporal regulation of focal adhesion kinase activity in living cells. | Q40060648 | ||
Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction | Q40172193 | ||
Contractility modulates cell adhesion strengthening through focal adhesion kinase and assembly of vinculin-containing focal adhesions. | Q40676349 | ||
EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas). | Q40716314 | ||
Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein | Q40796405 | ||
Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs | Q41334070 | ||
Axon initiation and growth cone turning on bound protein gradients. | Q42455214 | ||
Traction on immobilized netrin-1 is sufficient to reorient axons | Q42559709 | ||
Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix | Q42824269 | ||
Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion | Q43684842 | ||
Gene expression of EXT1 and EXT2 during mouse brain development | Q44366919 | ||
Dual functional activity of semaphorin 3B is required for positioning the anterior commissure | Q45345122 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 34 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mechanotransduction | Q11936292 |
P304 | page(s) | 11574-11585 | |
P577 | publication date | 2012-08-01 | |
P1433 | published in | Journal of Neuroscience | Q1709864 |
P1476 | title | Netrin-1 attracts axons through FAK-dependent mechanotransduction | |
P478 | volume | 32 |
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Q39203508 | Building branched tissue structures: from single cell guidance to coordinated construction. |
Q104578302 | Combinatorial nanodot stripe assay to systematically study cell haptotaxis |
Q38071551 | Engineered cell culture substrates for axon guidance studies: moving beyond proof of concept |
Q36092322 | FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones |
Q28821461 | Frazzled promotes growth cone attachment at the source of a Netrin gradient in the Drosophila visual system |
Q56530206 | Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance |
Q30357093 | Guidance of Axons by Local Coupling of Retrograde Flow to Point Contact Adhesions |
Q91777766 | Large-scale microfluidic gradient arrays reveal axon guidance behaviors in hippocampal neurons |
Q52652716 | MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation. |
Q58763383 | MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network |
Q36545296 | MUC4-promoted neural invasion is mediated by the axon guidance factor Netrin-1 in PDAC |
Q37398116 | Matrix mechanics controls FHL2 movement to the nucleus to activate p21 expression. |
Q26799030 | Mechanochemical regulation of growth cone motility |
Q36515258 | Mechanosensitive TRPC1 channels promote calpain proteolysis of talin to regulate spinal axon outgrowth |
Q36122457 | Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells. |
Q37148339 | Motor neuron-derived Thsd7a is essential for zebrafish vascular development via the Notch-dll4 signaling pathway. |
Q41296224 | Netrin-1 Regulates Fibrocyte Accumulation in the Decellularized Fibrotic Sclerodermatous Lung Microenvironment and in Bleomycin-Induced Pulmonary Fibrosis |
Q41612676 | Netrin-1 promotes gastric cancer cell proliferation and invasion via the receptor neogenin through PI3K/AKT signaling pathway |
Q37269416 | Netrin-1 suppresses the MEK/ERK pathway and ITGB4 in pancreatic cancer |
Q45345116 | Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord |
Q27323978 | Optogenetic activation of axon guidance receptors controls direction of neurite outgrowth |
Q47749103 | Progressive disorganization of paranodal junctions and compact myelin due to loss of DCC expression by oligodendrocytes |
Q37697825 | Regeneration of Aplysia bag cell neurons is synergistically enhanced by substrate-bound hemolymph proteins and laminin |
Q91854213 | Sensory innervation in porous endplates by Netrin-1 from osteoclasts mediates PGE2-induced spinal hypersensitivity in mice |
Q90366914 | Subchondral bone osteoclasts induce sensory innervation and osteoarthritis pain |
Q37724310 | Superparamagnetic Iron Oxide Nanoparticle-Mediated Forces Enhance the Migration of Schwann Cells Across the Astrocyte-Schwann Cell Boundary In vitro |
Q36449307 | The E3 Ubiquitin Ligase TRIM9 Is a Filopodia Off Switch Required for Netrin-Dependent Axon Guidance. |
Q28085404 | The discovery of the growth cone and its influence on the study of axon guidance |
Q38255120 | The diverse roles and multiple forms of focal adhesion kinase in brain. |
Q30357240 | The mTOR-FAK mechanotransduction signaling axis for focal adhesion maturation and cell proliferation. |
Q37719275 | The soft mechanical signature of glial scars in the central nervous system |
Q58058770 | Tuning neuron adhesion and neurite guiding using functionalized AuNPs and backfill chemistry |